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Oruro city in the Bolivian highlands depends solely on groundwater to supply domestic consumption and irrigation. The top porous aquifer currently exploited is not fully understood in aspects like geometry, hydrogeological properties and interaction with other aquifers in the region. Recent studies detected traces of fractures in the bedrock beneath the porous aquifer; these geological structures
With complete genealogical and cohabitation information, new genetic-epidemiological designs can be developed to clarify causes of parent-offspring transmission. We propose the Multiple Parenting Relationships (MPR) Design and apply it to drug abuse (DA) and alcohol use disorder (AUD). Using national Swedish registries, we identified four kinds of informative parents with multiple children with wh
This chapter uses the mass-conservation equations for CO2 and its isotopomers 13CO2 and CO18O that can be used to infer globally biospheric and oceanic net fluxes in the case of 18C, and gross terrestrial biospheric fluxes in the case of 18O. The quantitative use of atmospheric measurements of 13C and 18O in CO2 to better constrain those fluxes requires knowledge of various processes specific to e
With the elimination of Soviet state communism in the early 1990s, the ideational foundation of politics in the five Central Asian former Soviet republics had to undergo fundamental rebuilding. Instead of the defunct basis of Soviet-style Marxism-Leninism, the rulers of the suddenly independent Central Asian states urgently had to identify other ways and means of legitimizing their hold on power.
Background: The signal transducer and activator of transcription 3 (STAT3) pathway is observed to be constitutively activated in several malignancies including prostate cancer (PCa). In the present study, we investigated the expression of total STAT3 (tSTAT3) and two forms of activated phosphorylated STAT3 (pSTAT3
Digitalization offers unprecedented opportunities for entrepreneurial small and medium-sized enterprises (SMEs). However, many entrepreneurial SMEs lack resources and capabilities or suffer from inertia, which hampers these opportunities. This study investigates how entrepreneurial SMEs can enhance performance through digital platforms. Specifically, the study examines the effect of digital platfo
In social science discourse, the dichotomy between agency and structure tends to dominate debates pertaining to identity construction. When complex social facts are viewed through a simplistic prism of either individual activities or dominant structural impacts is likely to lead to a conclusion, - particularly when the subjects of research are members of communities at risk of vulnerability- which
Creativity is essential to knowledge production within universities and beyond. Yet, conditions for creativity receive scant scholarly attention as a feature of doctoral development, or as an element of institutional evolution within higher education. Even fewer authors have considered how creativity may be linked to doctoral students’ academic identity formation. In this paper, we analyse literat
Metal contamination of water bodies has attracted global attention owing to its environmental toxicity, abundance and persistence. Metals such as arsenic, cadmium and mercury are of greater concern since they are toxic even at low concentrations. Mercury is present at 1000 times lower concentrations than the other two metals, but still has a negative impact on the environment due to its high trans
Botulinum neurotoxins (BoNTs) are among the most potent toxins known and are also used to treat an increasing number of medical disorders. There are seven well-established serotypes (BoNT/A-G), which all act as zinc-dependent endopeptidases targeting specific members of the SNARE proteins required for synaptic vesicle exocytosis in neurons. A new toxin serotype, BoNT/X, was recently identified. It
What is the relationship between ballot reforms and electoral malpractice? This article contributes to the growing comparative politics literature on the causes of election fraud in democratizing countries using the case of the 19th-century United States. We examine the adoption of the Australian ballot and disenfranchisement laws, and estimate their effects on multiple types of election fraud. Us
BACKGROUND AND AIM: Many multilevel logistic regression analyses of "neighbourhood and health" focus on interpreting measures of associations (e.g., odds ratio, OR). In contrast, multilevel analysis of variance is rarely considered. We propose an original stepwise analytical approach that distinguishes between "specific" (measures of association) and "general" (measures of variance) contextual eff
This chapter discusses some aspects of various separation technologies applied in bioethanol production from lignocellulosic materials. Bioethanol can be produced from lignocellulosic biomass using several different process configurations. The main energy-demanding process steps in lignocellulosic ethanol production are distillation to concentrate the ethanol, adsorption to remove the final conten
