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Vacuum-assisted wound closure (VAC®) therapy is considered to be superior to conventional dressings in the treatment of peri-vascular groin infections after vascular surgery at our department. Therefore, we wanted to perform an early interim analysis of clinical outcome in these seriously ill patients at risk for amputation and death. Patients were randomised to either VAC® (n = 5) or Sorbalgon® (
Needle stimulation (acupuncture) has recently been shown to increase blood flow in the tibialis anterior muscle and overlying skin in healthy subjects (HS) and patients with fibromyalgia (FM). The aim of the present study was to examine the effect of needle stimulation on local blood flow in the trapezius muscle and overlying skin in HS and two groups of patients suffering from chronic pain in the
The loop region of chymotrypsin inhibitor 2 from barley has been employed as a scaffold for testing the intrinsic propensity of a peptide fragment to form a secondary structure. The helix formation of the nine amino acid residue segment Lys-Gln- Ala-Val- Asp- Asn- Ala-Tyr-Ala of helix E from subtilisin Carlsberg has been studied by the construction of a hybrid consisting of chymotrypsin inhibitor
The prevalence of HCV genotypes in four republics of the former Soviet Union (Russia, Belarus, Moldova, and Uzbekistan) was investigated. Overall, 197 HCV isolates from 66 blood donors and 131 patients with chronic hepatitis were typed. Viral sequences from sera of infected subjects were amplified by nested RT-PCR using primers from the core region and typed by one or two techniques: (1) DNA enzym
The atmospheric effects of soot aerosols include interference with radiative transfer, visibility impairment, and alteration of cloud formation and are highly sensitive to the manner by which soot is internally mixed with other aerosol constituents. We present experimental studies to show that soot particles acquire a large mass fraction of sulfuric acid during atmospheric aging, considerably alte
The nuclear receptor peroxisome proliferator-activated receptor delta [PPARdelta/beta (NR1C2)] has been implicated in colorectal carcinogenesis by various molecular genetic observations. These observations have recently been supported by studies of activation of PPARdelta by pharmacological agents. Here we present the first report of the stimulation of breast and prostate cancer cell growth using
Sequence variation of antigenic proteins allows pathogens to evade antibody attack. The variable protein commonly includes a hypervariable region (HVR), which represents a key target for antibodies and is therefore predicted to be immunodominant. To understand the mechanism(s) of antibody evasion, we analyzed the clinically important HVR-containing M proteins of the human pathogen Streptococcus py
The association between childhood environmental tobacco smoke (ETS) exposure and adult cancer risk is controversial; we examined this relationship in never smokers within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Over an average of 10 years, 8,372 cases of cancer were diagnosed in 112,430 never smokers in EPIC. Childhood ETS was self-reported by participants a
It is widely believed that DC, but not macrophages, prime naïve T cells in vivo. Here, we investigated the ability of CD68-expressing cells (commonly defined as macrophages) in priming autoreactive T cells and initiating collagen-induced arthritis (CIA) in the mouse. For this purpose, a transgenic mouse was developed (MBQ mouse) where macrophages exclusively expressed the MHC class II H2-A(q) (A(q
Even though researchers have investigated the growth of small and medium-sized enterprises (SMEs) for decades, we know little about the challenges they face due to their growth, what are the aspects of the context in which they emerge, and how they are addressed. Current literature provides even less knowledge about the causality of SME growth. This study, in the form of an explorative single case
The consumption and production of livestock have a negative impact on the environment and climate. In many Western countries, the consumption is particularly high and it is expected to increase globally. This increase will lead to further pressure on already stressed planetary boundaries. Recently edible insects have been proposed to be an alternative to conventional meat, because they have a lowe
Vi ser en förändring i relationen mellan det samtida individualiserade jaget och en ny typ av emotionell marknadsföring. Genom att undersöka det svenska rakhyvel-företaget Estrids Instagramflöde och image tar vi reda på om och hur dessa kan tänkas genomsyras av denna emotionella cool-kapitalism. Med hjälp av teorier grundade i postfeminism, transparens och audience labour utreder vi den roll emoti
A goal of entrepreneurship is to foster innovation through the creation of sustainable, scalable firms through a successful commercialization of their value proposal. Surprisingly there is little research on the key role sales and hence sales knowledge of the founder plays in the survival of an entrepreneurial venture. The purpose of this study is twofold. First, we aim to contribute to the wider
The experience drawn from the wars in the early modern era in Europe suggest that interstate wars lead to centralization of power and resources. These wars are also strongly associated with state building and were a crucial component in the formation of the modern state. Though another dynamic can be perceived in contemporary warfare. The wars we see today differ in actors, motives, methods of war
En nyligen utgiven studie från Södersjukhusets Akutmottagning för våldtagna visar att 70 procent av de tillfrågade våldtäktsoffren hade hamnat i ett tillstånd av frozen fright under övergreppet. Att ett offer hamnar i ett frystillstånd, frozen fright, innebär att förmågan att röra sig eller ge ljud ifrån sig minskas eller försvinner helt eftersom offrets utsätts för en traumatisk upplevelse. DennaA recently published study from Stockholm South General Hospital Emergency Clinic for Rape Victims shows that 70 per cent of the questioned victims had experienced a state of frozen fright during the rape. Frozen fright means a diminished or absent volitional movement accompanied by diminished vocal capacity in response to a traumatic event. The purpose of this thesis is to examine the perceptions
This dissertation will analyze how fashion and language is used to create stereotypes in film. Sex and the City will be used as the case study and the aim is to analyze the correlation between fashion and language in the making of the four main characters stereotypes. we will analyze these following questions: Why and in which way is fashion being used in Sex and the City to express sterotypes, an
This essay poses the question: To what extent does accession to the European Union lead to an improvement of media freedom and media plurality, and to what extent does a Europeanization of media occur? The essay focuses on the developments of the Central and Eastern European countries and focuses on Croatia and Czechia as the analyzed cases. In answering this question, the various theories of Euro
Popular Abstract in Swedish Mitralisklaffen (lat. valva mitralis; valva bicuspidalis) är den klaff i hjärtat som finns mellan vänster förmak och vänster kammare. Till utseendet liknar klaffen påvens huvudbonad, mitra, varifrån namnet härstämmar. Mitralisklaffen består av två segelliknande flikar (klaffblad) med en upphängningsapparat som fäster sig i vänster-kammarens vägg. När vänster kammare konNormalization of life expectancy after mitral valve surgery is highly dependent on early diagnosis and referral for surgical treatment. Among cases treated surgically, the majority (60–70%) have a degenerative etiology, which is also easiest to repair. The general aim of this thesis was to bring research on treatment of degenerative mitral regurgitation a step further in order to improve clinical
Patients with diabetes mellitus have more extensive coronary artery disease, more disease progression, and restenosis. The use of drug-eluting stents (DES) in these patients is widespread, despite uncertain long-term safety and efficacy. All consecutive patients with diabetes mellitus in Sweden who underwent percutaneous coronary intervention were entered into the Swedish Coronary Angiography and
