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Background: Apolipoprotein B (apoB) is a well-known risk factor for atherosclerosis. However, studies examining its relation to atrial fibrillation (AF) have produced conflicting results and suggested possible sex-specific differences. This study investigated the sex-specific associations between serum apoB concentrations and incident AF and offer insight into the inconsistencies in previous resea
Serglycin (SRGN) has been found overexpressed and secreted in glioblastoma (GBM), associated with tumorigenic signaling and poor prognosis. In this study, we aimed to elucidate the involvement of SRGN in the unfolded protein response (UPR), an oncogenic signaling pathway implicated in protein recycling and cell fate. Herein, we developed stably transduced LN-18shSCR GBM cells, expressing high leve
The exploration of tunable superconductivity in strongly correlated electron systems is a central pursuit in condensed matter physics, with implications for both fundamental understanding and potential applications. The Laves phase CeRu2, a pyrochlore compound, exhibits a three-dimensional (3D) kagome lattice type geometry giving rise to flat bands and degenerate Dirac points, where band structure
The interplay between superconductivity and charge or spin order is a key focus in condensed matter physics, with kagome lattice systems providing unique insights. The kagome superconductor LaRu3Si2 (Tc ≃ 6.5 K) features a characteristic kagome band structure and a hierarchy of charge order transitions at Tco,I ≃ 400 K and Tco,II ≃ 80 K, along with an additional transition at T* ≃ 35 K associated
The two-dimensional kagome lattice is an experimental playground for novel physical phenomena, from frustrated magnetism and topological matter to chiral charge order and unconventional superconductivity. A newly identified kagome superconductor, Ta2V3.1Si0.9 has recently gained attention for possessing a record high critical temperature, TC = 7.5 K for kagome metals at ambient pressure. In this s
Purpose: The study aimed to describe patients’ experiences of physical, psychological, social, and existential symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation (allo-HCT). Methods: Quantitative and qualitative data were collected and analysed with descriptive methods as part of a large retrospective cross-sectional online survey of patients who und
Sustainable water resources management in arid and semi-arid areas needs robust models, which allow accurate and reliable predictive modeling. This issue has motivated the researchers to develop hybrid models that offer solutions on modelling problems and accurate predictions of groundwater potential zonation. For this purpose, this research aims to investigate the capability and robustness of a n
Owing to the complexity in the chemical composition of plant essential oils, they often display enhanced insecticidal activity when applied as a mixture. Although the insecticidal activity of plant essential oils has been gaining more attention recently, understanding in the mechanism of synergy has not been studied as much. In the present study, insecticidal activity of 28 individual essential oi
This article contributes to the literature on sexual harassment at work in China. It advances the theoretical claim that network silences contribute to the persistence of sexual harassment. With the aim of contributing to the understanding of how networksilences are maintained, we analyzed the #MeToo in China Archives 2018–2019. Three themes emerged explaining silences of sexual harassment: (1) th
Populärvetenskaplig sammanfattning: Krkonoše national park är beläget i Sudeterna vid gränsen mellan Tjeckien och Polen. Parken karakteriseras av stora variationer i altitud och ett mosaikliknande vegetationsmönster. Det komplexa landskapet medför svårigheter vid val av klassificeringsteknik och skala för produktion av tillförlitliga markanvändningskarteringar. Denna studie syftar i första hand tiThe Krkonoše National Park is located in the Sudetes mountain range at the Czech - Polish border. It is characterized by large variations in altitude and a mosaic vegetation pattern. The complex landscape raises the issues of appropriate classification techniques and scales. The first aim of this study is to produce a land cover map using 21 classes based on a rule-based classification system and
Extreme price changes are identified in the stock market and related to jumps in the price process. After such extreme events, a reverting (also called contrarian) trend is examined. There is evidence that the initial price change is often an overreaction, caused by the psychology of market participants, and that the subsequent reversal corrects for the temporary inefficiencies in the market. Conf
A likelihood-based discriminant for the identification of quark- and gluon-initiated jets is built and validated using 4.7 fb of proton-proton collision data at collected with the ATLAS detector at the LHC. Data samples with enriched quark or gluon content are used in the construction and validation of templates of jet properties that are the input to the likelihood-based discriminant. The discrim
The mycalesine butterfly genus Heteropsis Westwood, 1850 (Satyrinae: Mycalesina) has recently been conceived to be represented in three major palaeotropical regions (Madagascar, Africa and Asia), but there has been no formal taxonomic treatment covering this entire group. Studies aimed at understanding the evolutionary success of Mycalesina in the Old World tropics have been hampered by the lack o
BACKGROUND: Women with mutations in either the BRCA1 or the BRCA2 gene have a high lifetime risk of ovarian cancer. Oral contraceptives protect against ovarian cancer in general, but it is not known whether they also protect against hereditary forms of ovarian cancer.METHODS: We enrolled 207 women with hereditary ovarian cancer and 161 of their sisters as controls in a case-control study. All the
Objective: We characterized the vasodilatory effects of ANP, BNP, and CNP in human subcutaneous arterioles in vitro and the cutaneous microcirculation in vivo. Methods: The in vitro experiments were performed using wire myography and the responses were characterized by the use of inhibitors for nitric oxide (L-NAME), prostaglandin synthesis (indomethacin), or the endothelium-derived hyperpolarizat
A unique, continuous, fan-shaped belt of sandy landforms in the central-eastern Mazovian Lowland, Central Poland has been investigated using a multiproxy dataset of sediment physical properties and chronological framework. Although there are several previous studies of similar fan-like forms elsewhere in Central Poland, this central-eastern part has not been investigated in detail. A combined meth
