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Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by X-ray (DXA), may be convenient alternatives for evaluating osteoporosis and fracture risk. We performed a meta-analysis of genome-wide association (GWA) studies to assess the genetic determinants of heel broadband ultrasound attenuation (BUA; n
The electronic structure of cobalt phthalocyanine (CoPc) on Pt(111), graphene/Pt(111), and Au-intercalated graphene/Ni(111) is investigated by photoexcited electron spectroscopies: photoemission (XPS and UPS) and X-ray absorption spectroscopy (XAS or NEXAFS). For CoPc on Pt(111), significant changes of the shape of XPS and XAS spectra indicate a charge transfer from the metal substrate to the Co i
Background: Abdominal adhesions develop on da- maged peritoneal surfaces and constitute a significant health related problem. Previous animal studies have shown promising anti-adhesive effects when adminis- tering the polycation α-poly-L-lysine (αPL) and the polyanion poly-L-glutamate (PG) together. The ob- jective of the study was to examine the effect of these differently charged polypeptides wh
Fisheries management traditionally relies on stock assessments assuming discrete populations within large administrational areas. However, failing to account for sub-stock structuring may result in overestimation of the stocks' true harvest potential and unsustainable exploitation of small stock elements. Atlantic cod (Gadus morhua) frequently occurs in spatially segregated populations, some of wh
The abnormal activation of the Wnt/β-catenin pathway frequently occurs in colorectal cancer. The nuclear translocation of β-catenin activates the transcription of target genes that promote cell proliferation, survival, and invasion. The pro-inflammatory mediator leukotriene D4 (LTD4) exerts its effects through the CysLT1 receptor. We previously reported an upregulation of CysLT1R in patients with
The gamma Y moth selects to migrate in stronger winds compared to songbirds, enabling fast transport to distant breeding sites, but a lower precision in orientation as the moth allows itself to be drifted by the winds. Photo: Ian Woiwod. In Focus: Chapman, J.R., Nilsson, C., Lim, K.S., Bäckman, J., Reynolds, D.R. & Alerstam, T. (2015) Adaptive strategies in nocturnally migrating insects and so
Exacerbation of ST elevation associated with reperfusion has been reported in patients with myocardial infarction. However, the cause of the "reperfusion peak" and relation of its magnitude to the size of myocardial damage has not been explored. The aim of our study was to assess the correlation between the ST-dynamics during reperfusion, the myocardium at risk (MaR), and the infarct size (IS).
In this study, we test the knowledge corridor theory as an explanation of university professors' involvement in the early stages of research commercialisation. A statistical analysis was made of a sample of full professors from the engineering, natural sciences and medical faculties at a large public university in Sweden. The analysis shows that not only entrepreneurial experience but also private
Folk music programmes have been a major feature of higher education music departments across the Nordic region for several decades. Still, programmes that offer the opportunity to deeply study non-European music (other than jazz) are very rare in most of Europe, and programmes in music education that offer such opportunities at anything more than a superficial level had been virtually non-existent
1. To help meet the requirements of water legislation, palaeolimnology has been widely used to establish ‘reference conditions’ and restoration targets for lakes. However, its potential for assessing the necessity and appropriateness of different lake management activities has been less publicized. 2. With reference to selected case studies covering consultancy projects commissioned by UK conserv
After stroke, brain inflammation in the ischemic hemisphere hampers brain tissue reorganization and functional recovery. Housing rats in an enriched environment (EE) dramatically improves recovery of lost neurologic functions after experimental stroke. We show here that rats housed in EE after stroke induced by permanent occlusion of the middle cerebral artery (pMCAO), showed attenuated levels of
EU forest biomass demand is increasing rapidly under policy stimuli, as biofuels are important for EU utilities to reach EU 2020 renewables goal. The import of large amounts will be required, but stakeholders have sustainability concerns. Utilities are adopting self-regulatory certification schemes to reduce stakeholder pressures but the interplay between these efforts, stakeholder and policy dyna
The effect of axial forcing on the flame/vortex breakdown interaction is studied, with particular focus on the Precessing Vortex Core (PVC). Large Eddy Simulation (LES), together with a filtered flamelet model describing the subgrid combustion, is performed to study a lean premixed flame undergoing mass flow fluctuations in a wide range of frequencies and amplitude. In average, forcing at frequenc
Self-pressurization in a cylindrical ribbed tank which is partially filled with liquid hydrogen is investigated numerically under different rib spacing-to-height ratios. The Volume of Fluid (VOF) method is employed as well as a phase change model. Appropriate models are incorporated into the Ansys Fluent by the user-defined functions to carry out the computations. The ribbed surface is modeled as
This paper examines how material and emotional investments in childrearing are rendered culturally meaningful in Chinese middle-class families in Singapore, and its consequences for family life. The competitive education system is a major concern for families with young children, and parents often invest substantial resources and energy in their children’s upbringing. The ‘overburdening’ of middle
Abstract in UndeterminedPurpose – This paper seeks to develop an integrated framework to examine how entrepreneurs' work experience is associated with the generation of new business ideas. The framework combines human capital theory with theory and research on entrepreneurial learning.Design/methodology/approach – A statistical analysis on a sample of 291 Swedish entrepreneurs is conducted.Finding
ABSTRACT: Streptococcal toxic shock syndrome is most frequently associated with Streptococcus pyogenes of the M1 serotype. Simvastatin protects against M1 protein-induced acute lung damage, although downstream mechanisms remain elusive. Herein, we hypothesized that geranylgeranylation might regulate proinflammatory effects in M1 protein-induced lung injury. Male C57BL/6 mice received the geranylge
The adhesion molecule laminin α2 chain interacts with the dystrophin-glycoprotein complex, contributes to normal muscle function, and protects skeletal muscles from damage. Complete loss of the laminin α2 chain in mice results in a severe muscular dystrophy phenotype and death at approximately 3 weeks of age. However, it is not clear if the remaining members of the dystrophin-glycoprotein complex
The ATLAS experiment at the LHC has measured the Higgs boson couplings and mass, and searched for invisible Higgs boson decays, using multiple production and decay channels with up to 4.7 fb(-1) of pp collision data at root S = 7 TeV and 20.3 fb(-1) at root s = 8 TeV. In the current study, the measured production and decay rates of the observed Higgs boson in the gamma gamma, ZZ, WW, Z gamma, bb,
