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The Scandinavian Total Ankle Replacement (STAR) has been used widely in Europe and more recently in the United States. We studied the results of the single-coated and the double-coated STAR with long-term follow-up.

Constitutive activation of tyrosine kinases as a consequence of chromosomal translocations, forming fusion genes, plays an important role in the development of hematologic malignancies, in particular, myeloproliferative syndromes (MPSs). In this respect, the t(9;22)(q34;q11) that results in the BCR/ABL fusion gene in chronic myeloid leukemia is one of the best-studied examples. The fibroblast grow

Background: The electrocardiographic (ECG) diagnosis of acute myocardial infarction (MI) should be improved. This might be done either by regarding all 24 aspects (both positive and negative leads), or a subset hereof (e.g. 19-lead ECG), of the conventional 12-lead ECG or by using additional electrodes. The purpose of this study was to investigate the accuracy of the different ECG methods in diagn

Prior studies have found that firms often find it difficult to implement innovative pricing strategies, such as value-based pricing, due to the organizational barriers they face in the implementation process. This case study of a manufacturing firm’s implementation of value-based pricing through the use of customer value map analysis (CVMA) examines the effect of these organizational barriers. Key

High EGR rates combined with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy duty spark ignition Natural Gas engines. With stoichiometric conditions a three way catalyst can be used which means that regulated emissions can be kept at very low levels. Most of the heavy duty NG engines are diesel engines which are converted for SI operation.

In the context of multiple stressors such as land shortage and food insecurity, the thesis deals with gendered land and labour rights as a social aspect of food production in subsistence agriculture in sub-Saharan Africa. Using the Chiweshe communal area in Zimbabwe as an example, it identifies, investigates and draws conclusions on higher order social processes of gender, power and incremental in

The proper handling of alarms is crucial to automated process control. In practice, many alarms are only distractive and do not represent a fault situation. Here, a toolbox is proposed that aims to reduce the occurrence of the so called nuisance alarms. It is a general computerized tool that takes advantage of the control system's built-in functions, and is a first step to an enhanced overall alar

Popular Abstract in Swedish Avhandlingen studerar tillväxtfaktorernas reglering av uPA-systemet i endometriet, och betydelsen av uPA-receptorns (uPAR) aktivering i den endometriella angiogenesen. Tillväxtfaktorer är polypeptider, vilka fungerar som signalmolekyler i cellernas kommunikation. Tillväxtfaktorerna frisätts från sina ursprungsceller och binder sig till specifika receptorer på ytan av ceThe purpose of this thesis was to examine the role of growth factors and the urokinase plasminogen activator (uPA) system in human endometrial angiogenesis. Growth factors as well as progesterone increased expression of the main inhibitor of uPA (PAI-1) in primary cultures of endometrial stromal cells. EGF, TGF-beta1 and bFGF increased gene transcription whereas progesterone increased mRNA stabili

Popular Abstract in Swedish I gröna växters kloroplaster finns ett s.k. sHsp-protein (small Heat shock protein) som betecknas Hsp21. Det tillhör en grupp av hjälpar-protein som kallas molekylära chaperoner. Chaperoner hjälper andra proteiner så att de inte klibbar ihop, aggregerar och blir inaktiva. Två vattenskyende ytor som sammanförs aggregerar. Genom att särskilt aggregerings-benägna (vattenskThe chloroplast-localized small heat shock protein (sHsp) Hsp21 belongs to the family of alpha-crystallin like sHsps which form large oligomeric structures and protect partly unfolded aggregation-prone proteins against aggregation. The main focus for this thesis has been on the highly conserved methionines in Hsp21. These methionine residues are situated on one side of an amphipathic alpha-helix.

In the search for renewable vehicle fuels several different gasoline additives have been discussed and reviewed. Today bioethanol is the most commonly used option, but isobutanol is being proposed as a better alternative by many stakeholders, due to its superior fuel characteristics, e.g. energy density, oxygen content and vapor pressure. The research project “Glycerol-based isobutanol” has invest

Traffic characterization is of great importance in the analysis and dimensioning of modem telecommunication networks. In this paper, the microdynamics of some sets of traffic are investigated. The approach we use to study the microdynamics is Poissonification, which is away of transforming a point process into a Poisson process locally. We want to gain basic knowledge of how the traffic behaves on

BACKGROUND: Simultaneous contact allergies to epoxy resins based on diglycidyl ether of bisphenol A (DGEBA-R) or epoxy resins of the bisphenol F-type and the reactive diluent phenyl glycidyl ether (PGE) have been reported. The reason might be cross-reactivity, exposure to an epoxy resin system with PGE as a component, or contamination by PGE in the epoxy resin. AIMS: To study contamination by PGE,

Procollagen N-proteinase (EC 3.4.24.14) is the enzyme that specifically cleaves the NH2-terminal propeptides from type I procollagen. Two forms of N-proteinase with apparent molecular sizes of 300 and 500 kDa were found in partially purified preparations from fetal bovine tendon extracts. The 500-kDa form of enzyme was purified 16,000-fold with a recovery of 8% from the extracts of the tendons by

At low temperature, cell membrane functionality depends on adjustments of membrane phospholipid fatty acid (PLFA) composition. We here test the hypothesis that previous exposure to copper (Cu) may deteriorate tolerance to freezing temperatures because of Cu-induced changes of PLFA composition of cell membranes in the freeze-tolerant earthworm Dendrobaena octaedra. Cu levels and freezing temperatur

In order to influence every day clinical practice professional organisations issue management guidelines. Cross-sectional surveys are used to evaluate the implementation of such guidelines. The present survey investigated screening for glucose perturbations in people with coronary artery disease and compared patients with known and newly detected type 2 diabetes with those without diabetes in term

The Lymphedema Quality of Life Inventory (LQOLI) is an instrument developed for patients with different types of lymphedema. It contains physical, emotional, social, and practical dimensions and consists of 58 items, each with three sub items concerning life quality, daily life changes, and difficulties of changing and two items concerning life quality in general and in relation to lymphedema. The

To characterize the gene activity that may be required for neuronal survival and regeneration, we used the Affymetrix GeneChip Mu74A to screen 12000 genes and expressed sequence tag (EST) mRNA from L4 and L5 mouse dorsal root ganglia (DRG) 12 h and 24 h after sciatic nerve transection. At 12 h, we found 17 upregulated transcripts, and at 24 h, 49 that met our criteria of a significant 2-fold incre