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The rapid evolution of digital technologies such as Artificial Intelligence (AI) and the Internet of Things (IoT) has fundamentally altered how agreements are formed and executed. Automated contract formations occur when contracts are initiated, negotiated or concluded by software agents or systems with minimal or no human intervention. This presents challenges to traditional legal concepts such a
This thesis explores how welfare and sustainability are constructed, promoted, and contested within contemporary trade governance and specifically through looking at the EU–Mercosur Association Agreement and the 2026 report by Articulação dos Povos Indígenas do Brasil, representing the voice of the Indigenous people there, to explore how fair trade can be promoted in today’s world of volatile glob
Introduction. The fourth edition of the Transatlantic Orthopedic Surgery Webinar 2022 took place on December 12th, 2022. The main theme of the webinar was the treatment of crouch gait in children with cerebral palsy (CP). Speakers from Australia, Canada, China, Germany, India, Poland, Spain, Sweden, Turkey, the United Kingdom, and the United States participated. Results. The first general session
Wages earned by men are often used as an indicator of the material standard of living (MSoL). However, this indicator relies on several assumptions when used for comparisons across time and space. Considering these assumptions will improve estimates of the MSoL from wages. One necessary assumption is that households in the compared populations relied on the primary income of the male head of house
Introduction: Divers are reported to have a lower ventilatory response to elevated levels of carbon dioxide (CO₂) than non-divers. Hypoventilation with CO₂ retention during diving is potentially dangerous. It is unknown if CO₂ retention is largely inherited or develops during diving training. We aimed to investigate if a military dive training course would influence the ventilatory response to CO₂
Astrocytes play a crucial role in the onset and progression of amyotrophic lateral sclerosis (ALS), a fatal disorder marked by the degeneration of motor neurons (MNs) in the central nervous system. Although astrocytes in ALS are known to be toxic to MNs, the pathological changes leading to their neurotoxic phenotype remain poorly understood. In this study, we generated human astrocytes from induce
This paper reports the measurement of Higgs boson production in association with a tt¯ pair in the H→bb¯ decay channel. The analysis uses 140 fb-1 of 13 TeV proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider. The final states with one or two electrons or muons are employed. An excess of events over the expected background is found with an observed (expected
Recycling wood ash from burnt wood (back to the forest grounds) is of great ecological importance. However, the ash cannot be recycled directly after combustion. There are several reasons for this, one being the volatility of wood ashes. Mixing ash/dolomite/water in order to obtain granular material is one method to stabilize wood ashes. The main problem is predicting the quantity of water to be a
This article reports on an investigation of audit independence in the context of local public audit in Sweden. The article focuses on the influence of two different sets of interests. The results show that there is a risk that the way the results of the audit process are communicated and disseminated in an organization is influenced by political, as well as market, interests. The article reveals t
Purpose: In most previous studies of free-to-total serum prostate specific antigen (PSA) ratios, the specimens from patients with prostate cancer or those with benign prostatic hyperplasia (BPH) have not been highly characterized. We compared preoperative sera from post-radical prostatectomy patients with clinically significant cancers of at least 2 cm.3 to sera from those with BPH and large, biop
The MAM blood group system (International Society of Blood Transfusion [ISBT] 041) consists of one high-prevalence antigen to date, first detected in a 31-year-old woman during her third pregnancy. Epithelial membrane protein 3 (EMP3) was recently identified as the gene coding the MAM antigen. Six unique genetic variants have been described in EMP3 in 11 MAM- individuals. EMP3 is an 18-kDa glycopr
The goal of a medico-legal autopsy is primarily to determine the cause and manner of death. To this end, the pathologist often uses auxiliary analyses, including histology. However, the utility of routine histology in all medico-legal autopsies is unknown. Earlier studies on the utility of routine histology have shown inconsistent effects, with some studies recommending it and others rejecting it.
Background: Corticosteroids play a significant role in managing the vast majority of inflammatory and immunologic conditions. To date, population-based studies on knowledge and attitudes concerning corticosteroids are scarce. This study aims to comprehensively assess knowledge, perception, experience and phobia toward corticosteroid use among the general population in the era of COVID-19. Methods:
PurposeWe describe the design and implementation of the Malmö Breast ImaginG (M-BIG) database, which will support research projects investigating various aspects of current and future breast cancer screening programs. Specifically, M-BIG will provide clinical data to: 1. investigate the effect of breast cancer screening on breast cancer prognosis and mortality; 2. develop and validate the us
Following his acclaimed earlier study on mediumship and survival, Alan Gauld providesa more complete account of about 50 years of early studies on mediumship with a select group ofmediums (e.g., Mrs. Piper, Mrs. Leonard, Mrs. Dowden). He describes in detail why many if not mostof the criticisms against extraordinarily accurate accounts by these mediums do not hold waterwhen analyzed in detail. Gau
BackgroundRight ventricular (RV) function is a major determinant of outcome in patients with pulmonary hypertension. Cardiac magnetic resonance (CMR) is gold standard to assess RV ejection fraction (RVEFCMR), however this is a crude measure. New CMR measures of RV function beyond RVEFCMR have emerged, such as RV lateral atrio-ventricular plane displacement (AVPDlat), maximum emptying velocity (S’C
The aim of this article is to reveal how care workers in the home-help services handle the process when older people’s relocation to a residential home is under consideration. Since the care workers are engaged daily in defining care receivers’ needs and yet have no formal influence on care decisions in Sweden, the focus is on how they solve this dilemma. In this inductive study, the theoretical f
Procarboxypeptidase U [proCPU, thrombin-activatable fibrinolysis inhibitor (TAFI), EC 3.4.17.20] belongs to the metallocarboxypeptidase family and is a zymogen found in human plasma. ProCPU has been proposed to be a molecular link between coagulation and fibrinolysis. Upon activation of proCPU, the active enzyme (CPU) rapidly becomes inactive due to its intrinsic instability. The inherent instabil
