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I ett allt mer digitaliserat samhälle, så är omställningen påtaglig även inom läkemedelsindustrin. Kontrollsystemet Orbit utvecklades vid Lunds Universitets avdelning för kemiteknik, för att möjliggöra automatisering av nedströmsprocesser baserade på ÄKTA-system. Kontrollsystemet har en inbyggd simulator, som tillåter en användare att genomföra simulerade experiment istället för fysiska. Målet medIn an ever more digitilized society, the transition is palpable also in the pharmaceutical industry. The control system Orbit was developed at the department of chemical engineering at Lund University, to be able to automate downstream processes based on the ÄKTA-system. The control system has a built-in simulator, enabling the user to run simulated experiments instead of actual physical experimen

A prominent movement for change of the current food system is Vía Campesina, a peasants’ movement advocating that food policy should incorporate perspectives from the most affected. Since the 1990s, international organisations (IOs) have opened up to non-state actors, allowing movements like Vía Campesina to occupy spaces ‘inside’ organisations instead of opposing from the ‘outside’. This thesis e

L'exposition des sociétés au changement climatique exige des villes qu'elles répondent de manière adéquate aux pressions environnementales croissantes tout en garantissant le bien-être des citoyens. La planification urbaine durable est un outil important à cet égard. Malmö est un pionnier du développement urbain durable salué au niveau international, mais critiqué pour ses déficits en mati

It is the primary purpose of this thesis to examine the relationship between public debt and population change for Japan. The study also aims to analyse if government revenues and interest rates could affect the future Japanese debt-to-GDP ratio. Consequently, through the use of an adapted form of the Romer model of economic growth, the study first creates future predictions of how the Japanese GD

The surge in multinational corporations and increased globalization have brought substantial attention to Foreign Direct Investment (FDI), a business phenomenon of considerable importance. Nevertheless, the global distribution of FDI is rather uneven, with transition countries being especially problematic. Although FDI has been assigned a crucial role in raising capital during structural changes t

Since Robotic Process Automation (RPA) is expected to have the potential of bringing substantial benefits to many of today’s businesses, RPA initiatives are taking an increasingly bigger role in various organizations. Previous research has identified a lack of guidelines in successfully adopting RPA. This deficit includes, but is not limited to a knowledge gap in the adoption of RPA by IT service

In this study it is examined whether the amount of Foreign Direct Investments (FDI) is affected by terrorism in three developed countries in Europe from a time series approach. The countries that are examined are France, Spain and the United Kingdom. The time period is 1975-2016 and the observations are annual. In previous literature there is evidence that terrorism should have an impact on FDI. F

Syftet med den här uppsatsen är att undersöka om det är möjligt att en nationell och restriktiv vapenreglering införs i USA, liknande den som finns i Australien, utan att det strider mot det andra tillägget i den amerikanska konstitutionens rättighetsstadga. Efter massakern i Port Arthur 1996 reformerade Australien sina vapenlagar genom antagandet av National Firearms Agreement (NFA), vilket innebThe aim of this thesis is to assess whether the Second Amendment to the United States (U.S.) Constitution prevents the U.S. from adopting an Australian style of gun control. In the aftermath of the Port Arthur massacre in 1996, Australia completely reformed its gun control legislation by enacting strict and uniform gun control laws under the National Firearms Agreement (NFA). While Australia’s gun

Conditionality clauses in EU trade agreements are widely criticised for their inefficacy in influencing companies’ production processes. While it is usually customary that companies that fail to comply to said clauses may still continue to export to the single market, the new 2016 trade agreement between the EU and Jordan has imposed stricter restrictions and forbids non-compliant companies to exp

Perceptions of where the “natural” place for women is, vary considerably across societies. This is especially true in heterogeneous countries like Ethiopia, where stark variations between ethnicities and their attitudes towards gender roles exist. A much-debated question is how these differences emerge. Some research suggests that gender roles originated from traditional agricultural practices whe

Gender constitutes an important determinant of mental health. Previous research has pointed out the need to investigate and operationalize the concept of gender beyond two distinct categories to account for the social and relational aspects of gender that may influence mental health outcomes. In this thesis I investigate the influence of gender-related norms on mental health outcomes among wome

INTRODUCTION: An increasing number of sub-Saharan African countries are implementing national health insurance schemes (NHISs) to support the aspiration of universal health coverage (UHC). A growing body of literature recognises the private sector role in improving NHIS equity in service access, public provider complementarity and overall member satisfaction. Zambia has implemented the NHIS since

Introduction: Moral distress arises when healthcare workers face difficult decisions without adequate information and/or when patient care is compromised due to limited resources, communication issues, or altered work routines in exceptional circumstances. While moral distress in maternity and neonatal healthcare workers (MNHCWs) has been noted, its prevalence, intensity, and impact on well-being

Release of halide ions is an essential step of the catalytic cycle of haloalkane dehalogenases. Here we describe experimentally and computationally the process of release of a halide anion from the buried active site of the haloalkane dehalogenase LinB. Using stopped-flow fluorescence analysis and umbrella sampling free energy calculations, we show that the anion binding is ion-specific and follow

The X-ray flux from X-ray free-electron lasers and storage rings enables new spatiotemporal opportunities for studying in-situ and operando dynamics, even with single pulses. X-ray multi-projection imaging is a technique that provides volumetric information using single pulses while avoiding the centrifugal forces induced by conventional time-resolved 3D methods like time-resolved tomography, and

BACKGROUND AND OBJECTIVES: The aim of the INveStigating ProblEmatic Clinical Trials in Systematic Reviews (INSPECT-SR) project is to develop a tool to identify problematic RCTs in systematic reviews. In stage 1 of the project, a list of potential trustworthiness checks was created. The checks on this list must be evaluated to determine which should be included in the INSPECT-SR tool.METHODS: We at

Amongst the impacts of climate change, those arising from extreme hydrological events are expected to cause the greatest impacts. To assess the changes in temperature and precipitation and their impacts on the discharge in the upper Yangtze Basin from pre-industrial to the end of 21st century, four hydrological models were integrated with four global climate models. Results indicated that mean dis

BACKGROUND: The risk of breast cancer among hypertensive patients who use beta-blockers has attracted attention. However, the evidence is inconsistent and investigation of the dose-specific associations for subtypes of beta-blockers are limited.METHODS: By incorporating Swedish national registers, breast cancer risk was estimated in women with hypertension who used nonselective beta-blockers and b