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The cardiac hormone atrial natriuretic peptide (ANP) is a central regulator of blood volume and a therapeutic target in hypertension and heart failure. Enhanced ANP activity in such conditions through inhibition of the degradative enzyme neprilysin has shown clinical efficacy but is complicated by consequences of simultaneous accumulation of a heterogeneous array of other hormones. Targets for spe
Two studies conducted in Sweden tested predictions from the intersectional invisibility hypothesis for groups at the intersection of gender and sexual orientation. Results show that gender prototypes include an assumed heterosexual orientation, and that representations of sexual minority groups include a more complex interplay of gender and sexual orientation.
A number of scholars and industry professionals have claimed that there has been a ‘software-biased shift’ in the nature and direction of innovation, in that software development is a core part of innovation activities in firms across a wide array of industries. Empirical firm-level evidence of such a shift is still scant. In this paper, we employ new and unique firm-level survey data on the frequ
Besides reducing fuel demands and indoor air pollution, pyrolytic cooking stoves produce a by-product (biochar) that can improve soil fertility and serve as a sink for carbon sequestration. Most smallholder farmers in Africa depend on wood for fuel, suffer from exposure to smoke and soils in their cultivated farms are deteriorating. Biochar (bio-charcoal) production has potentials to reduce energy
Background: High red cell distribution width (RDW) has been increasingly recognized as a risk factor for cardiovascular diseases (CVDs), but the underlying mechanisms remain unknown. Our aim was to explore the associations between RDW and plasma proteins implicated in the pathogenesis of CVD using a targeted proteomics panel. Methods: RDW and 88 plasma proteins were measured in a population-based
Background: Obesity prevalence is increasing globally. Bariatric surgery is an effective treatment for severe and complex obesity resulting in significant and sustained weight loss. In Sweden, most bariatric surgery patients are referred by primary care physicians. We aimed to explore barriers for physicians to refer patients with severe and complex obesity for bariatric surgery. Methods: A questi
Terrestrial water storage (TWS) is a crucial indicator of regional water balance and water resources changes. Due to limited hydrological observations, we combined the Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow-On (GRACE-FO) products using the Long Short-Term Memory (LSTM) neural network to monitor the TWS changes from April 2002 to March 2020 over the closed Qaidam Basin in
Crowdfunding is emerging as a significant means by which to finance and advance the 17 United Nations Sustainable Development Goals (SDGs). Generating financial support for the SDGs is now of even more importance because of the economic impacts of COVID-19. However, little research on sustainability crowdfunding has been conducted, particularly with respect to how behavioral influences, such as pe
Allozyme variation was studied in Swedish populations of Silene vulgaris (a widespread weed), S. uniflora ssp. uniflora (restricted to coastal habitats) and S. uniflora ssp. petraea (endemic to Sweden and confined to open limestone habitats). The taxa are diploid, gynodioecious, perennial herbs and showed high levels of within-taxon and within-population gene diversity at four polymorphic loci. Wi
The genetic control of variation at the Pgi‐2, Pgm‐1, Pgm‐2, and Tpi‐1 loci was investigated for the gynodioecious bladder campions, Silene uniflora and S. vulgaris. The main objective of the study was to determine whether alleles 1 and 2 at Pgi‐2, which have closely similar electrophoretic mobilities, were genuine Mendelian alleles. The results from a series of crossing experiments were consisten
Objectives The recovery after tonsil surgery is often troublesome for children and caregivers often feel insecure regarding optimal post-operative care for their children at home. The aim was to study what the current literature reports regarding the effect of post-operative telephone counselling and Internet support on pain and recovery after paediatric tonsil surgery. Method A systematic literat
Silene latifolia (white campion) is widespread in W Eurasia and shows clinal variation in seed morphology. Two extensive parapatric races, within which seed morphology changes gradually with geographic distance, are separated by a transition zone where the morphological gradient is steeper. A sample of seeds from across the species' native range was scored for morphological characters and analysed
Technology and innovation are important in addressing complex problems in the agricultural sector in many developing communities. However, ways and mechanisms to integrate them in the agricultural sector are still a challenge due to the lack of clear pathways and trajectories. Value chains are seen as a strong policy instrument to increase profitability in the agricultural sector; there is also de
