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The strong association between t(14;18) translocation and follicular lymphoma (FL) is well known. However, the determinants of this chromosomal aberration and their role in t(14;18) associated FL remain to be established.

Since the first heart transplantation (HT) in 1967, survival has steadily improved. Issues related to over- and under-immunosuppression are, however, still common following HT. Whereas under-immunosuppression may result in rejection, over-immunosuppression may render other medical problems, including infections, malignancies and chronic kidney disease (CKD). As such complications constitute major

This article critiques the notion of a cross-national convergence of institutional and policy responses to science-based technologies. The continued significance of institutional legacies is demonstrated through a comparative analysis of strategies for the biopharma industry in two radically different settings: India and the European Union (EU). Tensions are evident in both the EU 'high' route and

The ATP-binding cassette (ABC) of active transporters comprises a group of proteins that which facilitate efflux of anticancer drugs from cancer cells. We focused on the gene amplification and protein expression of ABCC3 (also known as MRP3) in breast cancer cell lines and clinical tumor samples. Fluorescence and chromogenic in situ hybridization, using an ABCC3-specific probe, was used to analyze

The climatic conditions inside nuclear reactor containments are continuously monitored by the plant owners in order to e.g. maintain a suitable climate for the mechanical and electrical equipment. Due to the high temperatures, during operation, the concrete within the containment may act as a moisture source contributing to the humidity. To evaluate if, and to what extent, the concrete inside the

ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to

We examine the role of substitution from traditional to modern energy carriers and of differential rates of innovation in the use of each of these in economic growth in Sweden from 1850 to 1950. We use a simple growth model with a nested CES production function and exogenous factor-augmenting technological change and carry out a counterfactual simulation based on the econometric results. Even thou

The Swedish Twin Registry (STR) today contains more than 194,000 twins and more than 75,000 pairs have zygosity determined by an intra-pair similarity algorithm, DNA, or by being of opposite sex. Of these, approximately 20,000, 25,000, and 30,000 pairs are monozygotic, same-sex dizygotic, and opposite-sex dizygotic pairs, respectively. Since its establishment in the late 1950s, the STR has been an

Classification of the open abdomen (OA) status is essential for clinical studies on the subject and may help to improve OA therapy. This is a validity and reliability analysis of the OA classification proposed by the World Society of the Abdominal Compartment Syndrome in 2013.

N-CAM, expressed by non-myelinating Schwann cells, was investigated by immunohistochemistry in transected rat femoral nerves, which were repaired either using a straight or a crossed over technique. N-CAM staining covered 30 and 11% of the cross-sectional area of and motor branches, respectively, in uninjured nerves. After 3 days there was a transient smaller area of N-CAM staining following both

In nearly all domains of Global Change Research (GCR), the role of humans is a key factor as a driving force, a subject of impacts, or an agent in mitigating impacts and adapting to change. While advances have been made in the conceptualisation and practice of interdisciplinary Global Change Research in fields such as climate change and sustainability, approaches have tended to frame interdiscipli

The milk metabolomes of 407 individual Swedish Red dairy cows were analyzed by nuclear magnetic resonance spectroscopy as part of the Danish-Swedish Milk Genomics Initiative. By relating these metabolite profiles to total milk protein concentration and rheological measurements of rennet-induced milk coagulation together using multivariate data analysis techniques, we were able to identify several

1. Freshwater communities are often structured by predation. In permanent lentic freshwater habitats dragonfly larvae are major predators which, in return, suffer predation by fish. Antipredator traits vary between the dragonfly species, and the dragonfly communities are therefore shaped by the presence of fish. But fish communities vary, and as different fish species affect dragonflies in differe

Background. Globally, general practitioners (GPs) write more than 90% of all antibiotic prescriptions. This study examines the experiences of Lithuanian and Russian GPs in antibiotic prescription for upper respiratory tract infections, including their perceptions of when it is not indicated clinically or pharmacologically. Methods. 22 Lithuanian and 29 Russian GPs participated in five focus group

Background. Cardiovascular (CVD) risk factors have been shown to cluster in some children. This has been shown in children from the age of nine years, but recently we found no clustering in six-year old children. It is uncertain when clustering develops and which parameters are related to the development of clustered CVD risk. Methods. A longitudinal study including 484 children aged six years. Th

The field of hypnosis anticipated the current interest in consciousness and has contributed in many ways to its conceptualization and research. This paper is divided into 3 sections. The first describes how hypnosis has enriched the study of alterations of consciousness, considered as dynamic processes subject to important individual differences. This section also considers how hypnosis offers an

The Neotropical jumping plant-louse Russelliana solanicola Tuthill is a potato pest and a probable vector of plant pathogens. Populations morphologically similar to those found on potatoes have been collected on plants of at least ten different families, four of which have been confirmed as hosts by the presence of immatures. This suggests that R. solanicola is either a single polyphagous species

We investigated neural distinctions between inflectional and derivational morphology and their interaction with lexical frequency using the mismatch negativity (MMN), an established neurophysiological index of experience-dependent linguistic memory traces and automatic syntactic processing. We presented our electroencephalography (EEG) study participants with derived and inflected words of variabl