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Association of the haptoglobin phenotype (1-1) with falciparum malaria in Sudan

The haptoglobin phenotypes of Sudanese patients with complicated and uncomplicated falciparum malaria, and those of uninfected randomly selected individuals, were determined by electrophoresis of sera on polyacrylamide gels followed by benzidine staining of the gels. Among 273 malaria patients, the proportions with haptoglobin phenotypes (1-1), (2-1) and (2-2) were 60.8%, 29.7% and 9.5%, respectiv

Formation of the alpha 1-microglobulin chromophore in mammalian and insect cells : a novel post-translational mechanism?

alpha 1-Microglobulin is an immunosuppressive plasma protein synthesized by the liver. The isolated protein is yellow-brown, but the hypothetical chromophore has not yet been identified. In this work, it is shown that a human liver cell line, HepG2, grown in a completely synthetic and serum-free medium, secretes alpha 1-microglobulin which is also yellow-brown, suggesting a de novo synthesis of th

Water Supplementation Reduces Copeptin and Plasma Glucose in Adults With High Copeptin : The H2O Metabolism Pilot Study

OBJECTIVE: Because elevated copeptin, a marker of vasopressin, is linked to low water intake and high diabetes risk, we tested the effect of water supplementation on copeptin and fasting glucose.DESIGN, SETTING, AND PARTICIPANTS: Thirty-one healthy adults with high copeptin (>10.7 pmol · L-1 in men and >6.1 pmol·L-1 in women) identified in a population-based survey from 2013 to 2015 and with a cur

Social media and organizing–An empirical analysis of the role of wiki affordances in organizing practices

The evolution of social media has introduced novel possibilities for work and interaction in organizations. The wiki technology is one important kind of social media technologies that is increasingly used to facilitate the creation and sharing of organizational knowledge within communities. Given the increasing use of social media in organizations and the lack of knowledge on their consequences fo

A new mouse model that spontaneously develops chronic liver inflammation and fibrosis

Here we characterize a new animal model that spontaneously develops chronic inflammation and fibrosis in multiple organs, the non-obese diabetic inflammation and fibrosis (N-IF) mouse. In the liver, the N-IF mouse displays inflammation and fibrosis particularly evident around portal tracts and central veins and accompanied with evidence of abnormal intrahepatic bile ducts. The extensive cellular i

DSM-III-R anxiety disorders in children: Sociodemographic and clinical characteristics

This study investigated the characteristics of each of the specific DSM- III-R (American Psychiatric Association, 1987) anxiety disorders in a clinic sample of 188 anxiety disordered children. Characteristics examined included sociodemographic variables (age-at-intake, gender, and race of the child, and family marital and socioeconomic status) and clinical variables (disorder age-at-onset and seve

Prevalence and risk factors for diabetic retinopathy at diagnosis (DRAD) in patients recently diagnosed with type 2 diabetes (T2D) or latent autoimmune diabetes in the adult (LADA)

Purpose To study prevalence of diabetic retinopathy (DR) at diagnosis (DRAD) and to estimate contributing risk by sociodemographic, cardiovascular and metabolic characteristics present in patients recently diagnosed with type 2 diabetes (T2D) or latent autoimmune diabetes in the adult (LADA). Methods Patients (n = 2174) recently diagnosed T2D (93%) or LADA (7%) were included upon arrival for their

On strategies of plant behaviour : Evolutionary games of habitat selection, defence, and foraging

Background: Strategies of habitat selection, defence, and foraging depend critically on population density and the frequency of alternative strategies: they are evolutionary games. Although commonly modelled in studies of animal behaviour, they are less frequently used to provide insights into the behaviour of plants. A 'review' and analysis of how these universal strategies apply to plants should

Human influences on evolution, and the ecological and societal consequences

Humans have dramatic, diverse and far-reaching influences on the evolution of other organisms. Numerous examples of this human-induced contemporary evolution have been reported in a number of ‘contexts’, including hunting, harvesting, fishing, agriculture, medicine, climate change, pollution, eutrophication, urbanization, habitat fragmentation, biological invasions and emerging/disappearing diseas

Retrofitting Electrically Heated Single-Family Houses to Net-Zero Energy

Only in Sweden, single-family houses account for approximately 30% of energy use in all buildings and a large part uses only electricity for heating. The potential for improvements on energy efficiency in these houses is large. This study theoretically investigates retrofitting of electrically heated Swedish single-family houses by using an air-source heat pump for both space heating and domestic

The second stage of labour - the use of interventions and women's experiences

AbstractThe overall aim of this thesis was to explore women´s experiences of the second stage of labour, midwifery practices and the use of interventions.Methods: Study I is a retrospective cohort study where 764 medical records from 2017 were reviewed. Women in Robson group 1 were included. Descriptive and analytic statistics were used to describe the use of oxytocin and to compare mode of birth

Comparative assessment of the bacterial communities associated with Anopheles darlingi immature stages and their breeding sites in the Brazilian Amazon

Background: The neotropical anopheline mosquito Anopheles darlingi is a major malaria vector in the Americas. Studies on mosquito-associated microbiota have shown that symbiotic bacteria play a major role in host biology. Mosquitoes acquire and transmit microorganisms over their life cycle. Specifically, the microbiota of immature forms is largely acquired from their aquatic environment. Therefore

The Influence of Surgeon Sex on Adverse Events Following Primary Total Hip Arthroplasty : A Register-Based Study of 11,993 Procedures and 200 Surgeons in Swedish Public Hospitals

BACKGROUND: Stereotypes may prevail, but little is known about the influence that the sex of an orthopaedic surgeon may have on outcomes. In a recently published study, there were no differences in the rate of adverse events following total hip arthroplasties (THAs) performed by female or male orthopaedic surgeons. The objective of the present study was to investigate whether there was any differe

An Experiment of Integrated Technologies in Digital Archaeology : Creation of New Pipelines to Increase the Perception of Archaeological Data

Abstract Digital visualization has gone through a revolutionary decade. Compared to other fields where these methods have been applied, archaeology has been, and still is, more resistant to integrating tools and instruments able to describe materials and scenarios with high resolution. This is partly due to the archaeological misconception of high cost of scientific equipment and the complexity in