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Through significant developments and progresses in the last two decades, in vivo localized nuclear magnetic resonance spectroscopy (MRS) became a method of choice to probe brain metabolic pathways in a non-invasive way. Beside the measurement of the total concentration of more than 20 metabolites, (1)H MRS can be used to quantify the dynamics of substrate transport across the blood-brain barrier b
In 2015 Afghans were the second largest group of asylum seekers in Sweden (and Europe). In this article, I analyze interviews conducted in early 2017 in Scania County with six adult male Afghan asylum seekers, an executive officer at the Swedish Migration Agency, the head of a private asylum seeker camp, and a voluntary worker. I show how the asylum seekers made their way to Sweden not so much thr
The paper presents results from a comparative study of selected biological and technical functions for thermal adaptability, which are based on an extensive literature review in biology and façade engineering. Several selected biological role models have been analysed in detail to identify their principles for dealing with thermal adaptation. These principles have been further abstracted through s
Type 2 diabetes (T2D) is a metabolic disease characterized by insufficient insulin secretion and insulin resistance. Disturbed beta-cell function is the final culprit that leads to the development of T2D. In addition, impaired incretin effect is likely a part of the pathogenesis of T2D. The aim of this thesis was to study the role of CART in beta-cells and incretin producing L- and K-cells.Endogen
Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the heritable risk of childhood acute lymphoblastic leukemia (ALL). To identify new susceptibility loci for the largest subtype of ALL, B-cell precursor ALL (BCP-ALL), we conducted a meta-analysis of two GWASs with imputation using 1000 Genomes and UK10K Project data as reference (totaling 1658 cases an
Essay for Vandalog about the search for Banksy's identity.
Our perception of time varies considerably from moment to moment, but how this variability relates to endogenous fluctuations in attentional states has been neglected. Here, we tested the hypothesis that perceptual decoupling during spontaneous mind wandering episodes distorts interval timing. In two studies with different visual subsecond interval timing paradigms, participants judged their atten
A systematic review of shaken baby syndrome by the Swedish Agency for Health Technology Assessment and Assessment of Social Services generated numerous reactions from professional organisations, even before the review was published. There was also a lively debate after a paper summarising its findings were published in Acta Paediatrica The various responses are worth debating further, as they rais
Parkinsons sjukdom (PS) är den näst vanligaste neurodegenerativa sjukdomen efter Alzheimers sjukdom och drabbar över 1 % av personer över 65 år. Även om denna progressiva och försvagande sjukdom brukar anses vara en motorsjukdom, med symtom som stelhet, långsamma rörelser och vilotremor, så påverkas också icke-motoriska funktioner som sömn, kognition och mag-tarmfunktion. Dessa symtom förekommer vParkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest.PD can be familial, where a single inherited gene mutation causes the disease, but most cases of PD (90%) a
In this paper, we investigate the effects of offshoring on workers' job security using matched employer-employee data from Sweden. For our observed period (1997-2011), while the share of firms engaged in offshoring fell during the period from around 25% to 22%, offshoring per worker within offshoring firms almost doubled. We make use of this variation to contribute to the literature on several fro
Human stature is a variable often used to study health changes in present and past populations. In this study possible differences in stature from the late Mesolithic-Early Bronze Age, based on skeletal data from southern Sweden, are investigated. The sample comprises n = 203 femora where maximum lengths were evaluated using non-parametric testing. Sex was assessed primarily using criteria on the
I Abstracts of the XXXVth International Congress on Law and Mental Health
The gut microbiome of animals is emerging as an important factor influencing ecological and evolutionary processes. A major bottleneck in obtaining microbiome data from large numbers of samples is the time-consuming laboratory procedures required, specifically the isolation of DNA and generation of amplicon libraries. Recently, direct PCR kits have been developed that circumvent conventional DNA e
This paper studies the disturbance rejection problem for sampled-data control systems, where disturbance signal occurs below and above the Nyquist frequency simultaneously. Two discrete-time controllers are designed via H∞ optimal control in two steps; at first a controller is designed to reject the low-frequency components, and then we construct the generalized plant including the first controlle
In situ Fourier transform infrared spectroscopy was used to study transient CO oxidation over a series of bimetallic Pd-Pt catalysts with different Pd:Pt molar ratios. The catalysts were found to contain both alloyed PdPt nanoparticles (particle sizes 25-35 nm) and monometallic Pd nanoparticles (sizes below 10 nm). For oxygen-free conditions, CO reduces the surface while simultaneously function as
In the 21st century, climate change in combination with increasing demand, mainly from population growth, will exert greater pressure on the ecosystems of the Sahel to supply food and feed resources. The balance between supply and demand, defined as the annual biomass required for human consumption, serves as a key metric for quantifying basic resource shortfalls over broad regions.Here we apply a
