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Development of a simulation method for transient response of fluid flow in pipes
The Chapman-Enskog Expansion: A Novel Approach to Hierarchical Extensions of Lighthill-Whitham Models
This paper suggests that the Payne models should not properly be regarded as the traffic flow analog of the Navier-Stokes equations of fluid dynamics. Further, the Chapman-Enskog asymptotic expansion in a small parameter is shown to lead to an alternate class of models that seem to have a more legitimate claim to that distinction. Details of this expansion, about the stable-flow equilibria of the
Operational Improvements for Start-Up Time Reduction in Solar Steam Turbines
Solar steam turbines are subject to high thermal stresses as a result of temperature gradients during transient operation, which occurs more frequently due to the variability of the solar resource. In order to increase the flexibility of the turbines while preserving lifing requirements, several operational modifications for maintaining turbine temperatures during offline periods are proposed and
Regional Cooperation on Innovation and Cluster Development
The Baltic Sea Region is rapidly becoming one of the world’s more competitive regions. The region is capitalising on its strengths and making the most of its diversity to stimulate innovation, build a strong pool of skilled labour and foster entrepreneurship. A deep spirit of co-operation and integration has led the Baltic Sea countries to set up ambitious governance frameworks to pursue economic
War Violence, Victimhood and Reconciliation: in Stories of Bosnian War Survivors
In this analysis of the retold experiences of 27 survivors of the war in northwestern Bosnia, the aim is to describe the informants’ portrayal of “war violence”, “victimhood”, and “reconciliation” as a social phenomenon as well as analyzing the discursive patterns that contribute to constructing the category “victim” and “perpetrator”. The violence practice during the war is portrayed as organized
Unusual process of water formation on RuO2(110) by hydrogen exposure at room temperature
The reduction mechanism of the RuO2(110) surface by molecular hydrogen exposure is unraveled to an unprecedented level by a combination of temperature programmed reaction, scanning tunneling microscopy, high-resolution core level shift spectroscopy, and density functional theory calculations. We demonstrate that even at room temperature hydrogen exposure to the RuO2(110) surface leads to the forma
Pancreatic juice protects gut from pathogenic bacteria
The role of the exocrine pancreas in regulating gut microflora colonization is unclear. The main objective in the present study was to assess the affect of pancreatic fluid on the growth of pathogenic bacteria and fungi. Pancreatic juice samples used in the study were obtained from nine eight-week old weaned pigs in which catheters were implanted in the pancreatic duct. The antibacterial activity
Main group atoms and dimers studied with a new relativistic ANO basis set
New basis sets of the atomic natural orbital (ANO) type have been developed for the main group and rare gas atoms. The ANO's have been obtained from the average density matrix of the ground and lowest excited states of the atom, the positive and negative ions, and the dimer at its equilibrium geometry. Scalar relativistic effects are included through the use of a Douglas-Kroll Hamiltonian. Multico
Protocol for Providing Additional Pseudo-Pregnant Recipient Mice for Embryo Transfer and Intra-Uterine Insemination by Plugging in the Middle of the Day
The fact that 10% of female mice enter oestrus and allow mating in the middle of the day is an old observation that has been more or less forgotten. We here show that this old knowledge can be used to improve the efficacy of both embryo transfer and insemination protocols. The present technical paper shows that rapid re-arrangements of mating cages, to achieve pseudo-pregnant recipients in the mid
Generation of an induced pluripotent stem cell line (CSC-46) from a patient with Parkinson's disease carrying a novel p.R301C mutation in the GBA gene
Mutations in the glucocerebrosidase (GBA) gene have been associated with the development of Parkinson's disease (PD). An induced pluripotent stem cell (iPSC) line was generated from a 60-year old patient diagnosed with PD and carrying a new mutation variant p.R301C in GBA. Using non-integrating Sendai virus-based technology, we utilized OCT3/4, SOX2, c-MYC and KLF4 transcription factors to reprogr
In Silico Identification and in Vitro Analysis of B and T-Cell Epitopes of the Black Turtle Bean (Phaseolus Vulgaris L.) Lectin
Background/Aims: The incidence of lectin allergic disease is increasing in recent decades, and definitive treatment is still lacking. Identification of B and T-cell epitopes of allergen will be useful in understanding the allergen antibody responses as well as aiding in the development of new diagnostics and therapy regimens for lectin poisoning. In the current study, we mainly addressed these que
Dislocation Generation from Grain Boundaries in Nanosized Cu-beams
As the dimensions of a structure are decreased towards the nanometer scale, the mechanical response to loading deviates from what is observed macroscopically. This is due to a change in material properties stemming from the relative increase in number of surface atoms as compared to bulk atoms. Surface atoms lack some of their neighboring atoms, leading to a reorganization of the electron clouds a
In-situ soot characterization of propane flames and influence of additives in a 100 kW oxy-fuel furnace using two-dimensional laser-induced incandescence
In-situ soot characterization has been successfully performed in a 100 kWth down-fired oxy-fuel test furnace using laser-induced incandescence (LII) and extinction measurements. Primarily non-premixed propane flames were investigated in oxy-fuel mode with various concentrations of oxygen in the oxidant. The turbulent flame character was manifested through two-dimensional single-shot LII signals fr
Hypothermia After Cardiac Arrest in Large Animals (HACA-LA) : Study protocol of a randomized controlled experimental trial
Background: Induced hypothermia post-cardiac arrest is neuroprotective in animal experiments, but few high-quality studies have been performed in larger animals with human-like brains. The neuroprotective effect of postischemic hypothermia has recently been questioned in human trials. Our aim is to investigate whether hypothermia post-cardiac arrest confers a benefit compared to normothermia in la
Effect of level of sedation on outcomes in critically ill adult patients : a systematic review of clinical trials with meta-analysis and trial sequential analysis
Background: Sedation is routinely administered to critically ill patients to alleviate anxiety, discomfort, and patient-ventilator asynchrony. However, it must be balanced against risks such as delirium and prolonged intensive care stays. This study aimed to investigate the effects of different levels of sedation in critically ill adults. Methods: Systematic review with meta-analysis and trial seq
Distributed attitude synchronization control
In this paper we consider the problem of constructing feedback control laws for a system of n agents that shall synchronize their attitudes in SO(3). We propose distributed controllers for two synchronization problems, in which the objective is the same, to synchronize the orientations, but what the agents can perceive or communicate differs. In the first problem the agents can measure their orien
Parenting, Family Policy and Gender
EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes
Adipocytes play a central role in energy balance, and dysfunctional adipose tissue severely affects systemic energy homeostasis. The ATPase EH domain-containing 2 (EHD2) has previously been shown to regulate caveolae, plasma membrane-specific domains that are involved in lipid uptake and signal transduction. Here, we investigated the role of EHD2 in adipocyte function. We demonstrate that EHD2 pro
Quantitative versus standard pupillary light reflex for early prognostication in comatose cardiac arrest patients : an international prospective multicenter double-blinded study
Purpose: To assess the ability of quantitative pupillometry [using the Neurological Pupil index (NPi)] to predict an unfavorable neurological outcome after cardiac arrest (CA). Methods: We performed a prospective international multicenter study (10 centers) in adult comatose CA patients. Quantitative NPi and standard manual pupillary light reflex (sPLR)—blinded to clinicians and outcome assessors—
