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Frailty causes disability and restrictions on older people's ability to engage in leisure activities and for social participation. The objective of this study was to evaluate the effects of a 1-year case management intervention for frail older people living at home in Sweden in terms of social participation and leisure activities. The study was a randomised controlled trial with repeated follow-up

The aim of the Massive Open Online Course (MOOC) ‘Work and Technology on Human Terms’ was to be a modern, highly accessible study material in Ergonomics/Work science to contribute to safer and healthier workplaces. The course targets engineering students, but also students in economics, human relations, physiotherapy, occupational health, as well as professionals. The purpose of this paper is to d

The Massive Open Online Course (MOOC) ‘Work and Technology on Human Terms’ (www.onhumanterms.org ) was launched in July 2017 with the aim to contribute to safer and healthier workplaces by increasing the knowledge about how products, systems, and work organizations can be designed on human terms. The purpose of this paper is to present the results of a first evaluation of the MOOC. The online cour

The most important goals for the field of immuno-oncology are to improve the response rate and increase the number of tumor indications that respond to immunotherapy, without increasing adverse side effects. One approach to achieve these goals is to use tumor-directed immunotherapy, i.e., to focus the immune activation to the most relevant part of the immune system. This may improve anti-tumor eff

Laser-induced incandescence (LII), elastic light scattering (ELS) and extinction were used to investigate the early stages of soot formation when seeding metal salts at various concentrations into a premixed ethylene/air flame on a PerkinElmer burner. The investigation contained seven salts, where we in this work mainly focus on two of these salts, potassium chloride (KCl) and iron chloride (FeCl3

For the first time, laser-induced thermal grating spectroscopy (LITGS) in the spectral range around 3. μm is demonstrated as a versatile diagnostic tool. This spectral region is of particular interest in combustion diagnostics as many relevant species such as hydrocarbons and water exhibit fundamental vibrational modes and hence can be probed with high sensitivity. Another benefit of the IR-LITGS

Short leukocyte telomere length (LTL) may be associated with several psychiatric disorders, including major depressive disorder (MDD). Short LTL has previously been associated with poor response to psychiatric medications in bipolar disorder and schizophrenia, but no studies have prospectively assessed the relationship of LTL to SSRI response in MDD. We assessed pre-treatment LTL, depression sever

ObjectivesTo identify cytokines that can activate and expand NK cells in the presence of prostate cancer cells in order to determine whether these agents may be useful in future intra‐tumoural administration in pre‐clinical and clinical prostate cancer trials.Materials and MethodsLymphocytes isolated from normal donor blood were set up in co‐cultures with either cancer or non‐cancerous prostate ce

In this section of the European Resuscitation Council Guidelines 2021, key information on the epidemiology and outcome of in and out of hospital cardiac arrest are presented. Key contributions from the European Registry of Cardiac Arrest (EuReCa) collaboration are highlighted. Recommendations are presented to enable health systems to develop registries as a platform for quality improvement and to

Accurate atomic data are essential for opacity calculations and for abundance analyses of the Sun and other stars. The aim of this work is to provide accurate and extensive results of energy levels and transition data for C i–iv. The Multiconfiguration Dirac–Hartree–Fock and relativistic configuration interaction methods were used in this work. To improve the quality of the wavefunctions and reduc

This chapter proposes a novel ethnographic approach to global crime/criminology-an approach centered on the following four main points: (1) an attentiveness to how global dynamics afford criminal flows and transnational figurations; (2) a theoretical and methodological sensibility that moves beyond methodological nationalism; (3) a research design that follows criminal flows, rather than merely in

This study aims to explore how physicians make sense of and give meaning to their decision-making during obstetric emergencies. Childbirth is considered safe in the wealthiest parts of the world. However, variations in both intervention rates and delivery outcomes have been found between countries and between maternity units of the same country. Interventions can prevent neonatal and maternal morb

As the dimensions of a structure are decreased towards the nanometer scale, the mechanical response to loading deviates from what is observed macroscopically. This is due to a change in material properties stemming from the relative increase in number of surface atoms as compared to bulk atoms. Surface atoms lack some of their neighboring atoms, leading to a reorganization of the electron clouds a

In-situ soot characterization has been successfully performed in a 100 kWth down-fired oxy-fuel test furnace using laser-induced incandescence (LII) and extinction measurements. Primarily non-premixed propane flames were investigated in oxy-fuel mode with various concentrations of oxygen in the oxidant. The turbulent flame character was manifested through two-dimensional single-shot LII signals fr

An N-body code containing live stellar evolution through combination of the software packages nbody6 and stars is presented. Operational details of the two codes are outlined and the changes that have been made to combine them discussed. We have computed the evolution of clusters of 104 stars using the combined code and we compare the results with those obtained using nbody6 and the synthetic stel

There is an apparent dichotomy between the metal-poor ([Fe/H] ≤ -2) yet carbon-normal giants and their carbon-rich counterparts. The former undergo significant depletion of carbon on the red giant branch after they have undergone first dredge-up, whereas the latter do not appear to experience significant depletion. We investigate this in the context that the extra mixing occurs via the thermohalin

The utility of mRNA and protein determinations of G protein-coupled receptor 35, that is, GPR35a (GPR35 V1) and GPR35b (GPR35 V2/3), as indicators of outcome for colon cancer patients after curative surgery was investigated. Expression levels of V1 and V2/3 GPR35, carcinoembryonic antigen and CXCL17 mRNAs were assessed in primary tumours and regional lymph nodes of 121 colon cancer patients (stage