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The presence of serotonin (5-hydroxytryptamine [5-HT]) in pancreatic endocrine cells is well established. Nevertheless, recent advances are only now unraveling the signaling network involving 5-HT that partly regulates the release of hormones emanating from the islets of Langerhans. It is widely accepted that failure of the pancreatic β-cell to release sufficient amounts of insulin is the main cul
One approach to assessing overall opinion polarity (OvOP) of reviews, a concept defined in this paper, is the use of supervised machine learning mechanisms. In this paper, the impact of lexical filtering, applied to reviews, on the accuracy of two statistical classifiers (Naive Bayes and Markov Model) with respect to OvOP identification is observed. Two kinds of lexical filters, one based on hyper
Focusing on Western tourism behind the Iron Curtain, this chapter introduces the main research questions addressed in the volume: firstly, how and why Eastern Europe became a tourist destination for citizens of the West; secondly, what impact this had on the development of a tourism industry in the Eastern bloc; and thirdly, to what extent the experiences of Western tourists in Eastern Europe infl
We investigated the quality of life (QoL) of newly diagnosed persons with cancer aged 65 years at baseline and 3 months after, in relation to age, contact with the healthcare system, activities of daily living, hope, social network and support using the European Organization for Research and Treatment of Cancer QLQ-C30, Katz ADL, Nowotny's Hope Scale, and the Interview Schedule for Social Interact
An introduction to the anthology Perspectives on the Entangled History of Communism and Nazism. A Comnaz Analysis.
RATIONALE: Obstructive sleep apnea (OSA) and depression are common among adults with coronary artery disease (CAD). OBJECTIVES: To determine the impact of continuous positive airway pressure (CPAP) treatment on depression in adults with CAD and nonsleepy OSA. METHODS: This was a secondary analysis of the RICCADSA (Randomized Intervention with CPAP in CAD and Sleep Apnea) trial, conducted in Sweden
Heritopia explores the multiple meanings of the past in the present, using the famous temples of Abu Simbel and other World Heritage sites as points of departure. It employs three perspectives in its attempt to understand and explain both past and present: the truth of knowledge, the beauties of narrative, and ethical demands. Crisis theories are rejected as nostalgic expressions of contemporary s
In a Λ cold dark matter (ΛCDM) cosmology, the Milky Way accretes satellites into the stellar disc. We use cosmological simulations to assess the frequency of near disc plane and higher inclination accretion events, and collisionless simulations of satellite mergers to quantify the final state of the accreted material and the effect on the thin disc. On average, a Milky Way-sized galaxy has three s
METHODS: This was a multicentre, international, observer-masked, randomised controlled trial of people with diabetes and a hard-to-heal foot ulcer done in 32 specialist diabetic foot clinics in three countries (UK, Denmark, and Sweden). After a 4-week run-in period, those with a reduction in ulcer area of less than 50% were randomly allocated (1:1) by computer-generated, web-based randomisation (b
A group of 38 male workers at a secondary smelter (period of employment 2-35 years; median 10 years) was divided into two subgroups depending on bone-lead concentration, arranged as 19 matched pairs according to age, education and job level. The median concentrations for finger-bone lead (Bone-Pb) were 16 vs. 32 μg/g; for current blood-lead (B-Pb), 1.6 vs. 1.8 μmol/l; for retrospective peak blood-
This study examines the effects of teachable agents’ expressed self-efficacy on students. A total of 166 students, 10- to 11-years-old, used a teachable agent-based math game focusing on the base-ten number system. By means of data logging and questionnaires, the study compared the effects of high vs. low agent self-efficacy on the students’ in-game performance, their own math self-efficacy, and t
Houses are prominent in many taxes in the Netherlands. In this chapter we analyze the situation of Dutch housing taxation in local and national taxes. We show that both are intertwined because of the use of one value which is determined at the local level, but used at the national level as well. We briefly discuss the balance between local and national taxation in the Netherlands, the relatively l
INTRODUCTION: : The aldosterone/renin ratio (ARR) is the first line screening test for primary aldosteronism (PA). However, in hypertensive patients with an increased ARR, PA needs to be confirmed by other means. METHODS: : A 25 mg oral captopril test was performed in 16 healthy subjects to obtain reference values for aldosterone and ARR at 120 minutes after the test. Subsequently these data were
Popular Abstract in Swedish En omorganisation av det svenska Vägverket har medfört ett behov för dem att fungera som en professionell beställare enbart, utan utförande i egen regi. Det har naturligtvis också medfört en förändring i hur man hanterar upphandlingen av vägunderhåll. En väghållares främsta uppgift är att underhålla befintliga anläggningar och se till at de fungerar som avsett. Den näsA reorganization of the Swedish National Road Administration (SNRA) has urged a demand to work as a professional agency only, without any work by direct labor. This structure has enforced a change in how to handle the pavement maintenance and performance contracts are being promoted since they encourage product development and sustainability. Furthermore, SNRA desires to use the road network as a
