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Several recent studies of solar twins in the solar neighbourhood have shown a tight correlation between various elemental abundances and age, in particular [Y/Mg]. If this relation is real and valid for other types of stars as well as elsewhere in the Galaxy, it would provide a very powerful tool to derive ages of stars without the need to resort to determining their masses (evolutionary stage) ve
In stable biological and ecological networks, the steady-state influence matrix gathers the signs of steady-state responses to step-like perturbations affecting the variables. Such signs are difficult to predict a priori, because they result from a combination of direct effects (deducible from the Jacobian of the network dynamics) and indirect effects. For stable monotone or cooperative networks,
The Øresund Region that connects Copenhagen metropolitan area in Denmark and Southern Sweden is an interesting example of a European cross-border collaboration. In this article, the contemporary development of the region and the place branding process is described. The aim is to increase understanding of how a complex and bi-national place brand is developed in a process of continuous change due t
This study investigates how public sector organizations generate authority in social media crisis. Furthermore, it examines how genres of governance, namely genre chain and genre mixing, contribute to the generation of authority. On this basis of an interdisciplinary theoretical framework consisting of the concepts of “network governance” and “authority,” a genre analysis of 100 top forwarded post
The contribution of Rafael Capurro to the clarification of the uses of the concept of information has a conceptual as well a historical dimension; in this last sense, there are few philosophers of information that can follow the history of the concept of information in the works of the Classics with the accuracy and erudition of Capurro We find that his contribution embraces the following fields:
Today’s communities are characterized by migration, transnationalism, and participation in the global economy, and many also have long local histories of linguistic diversity. Empowering individuals in these contexts means fostering the ability to use and expand their existing linguistic repertoires so they can take advantage of the social and economic opportunities afforded by contemporary life.
The base-quenched probe method for detecting single nucleotide polymorphisms (SNPs) relies on real-time PCR and melting-curve approaches. Here, we applied the most common commercial fluorophores including FAM, HEX, CY5, CY3, TET, JOE, Texas Red and ROX for labeling probes to detect multi-mutations simultaneously according to the different fluorescence channels. Accuracy of the method was confirmed
Introduction: The interaction between different product policies will be crucial for the further advancement of a coherent product policy framework. The Commission has stated that ‘the complex and interlocking approach needed to build a resource-efficient Europe can only be achieved with a policy mix that optimizes synergies and addresses trade-offs between different areas and policies’. In the co
Immune cell-derived cytotoxic pathways have been implicated in antitumor immune responses. The goal of this study is to characterize how these cytotoxic pathways influence ovarian cancer development. We have utilized the TgMISIIR-TAg transgenic mouse model which expresses the transforming SV40 TAg in the ovary, leading to spontaneous development of ovarian tumors that closely mimic human epithelia
This paper is partly a summary of the book ‘From a grain of salt to the ribosome’ [1], with extension on some points. Sometimes the developments in science may be very rapid and not fully appreciated at all corners of the scientific society. Harry Clary Jones was a well-known chemist at Johns Hopkins University at the turn of the previous century. He had, in his earlier days, spent time in the lab
Nucleotide-binding and oligomerization domain (NOD) -like receptors (NLRs) and retinoic acid-inducible gene (RIG) -like receptors (RLRs) are recently discovered cytosolic pattern-recognition receptors sensing mainly bacterial components and viral RNA, respectively. Their importance in various cells and disorders is becoming better understood, but their role in human tonsil-derived T lymphocytes re
colon; Prompted by previous studies suggesting that bulimia nervosa in women may be associated with elevated serum levels of testosterone, we have evaluated the possible effect of androgen antagonism in this condition. To this end, women meeting the DSM-IV criteria of bulimia nervosa, purging type, were treated in a one-center study with the androgen receptor antagonist flutamide (n = 9), the sero
Collagen type VI is a subepithelial extracellular matrix component in airways and an adhesive substrate for oral pathogens [Bober et al.: J Innate Immun 2010;2:160-166]. Here, we report that collagen VI displays a dose-dependent antimicrobial activity against group A, C, and G streptococci by membrane disruption in physiological conditions. The data disclose previously unrecognized aspects of the
