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Association of clopidogrel treatment with risk of mortality and cardiovascular events following myocardial infarction in patients with and without diabetes

CONTEXT: Pharmacodynamic studies have shown that persistently high platelet reactivity is common in patients with diabetes in spite of clopidogrel treatment. Clinical trials have not convincingly demonstrated that clopidogrel benefits patients with diabetes as much patients without diabetes.OBJECTIVES: To estimate the clinical effectiveness associated with clopidogrel treatment after myocardial in

Fully decentralized conditions for local convergence of DC/AC converter network based on matching control

We investigate local convergence of identical DC/AC converters interconnected via identical resistive and inductive lines towards a synchronous equilibrium manifold. We exploit the symmetry of the resulting vector field and develop a Lyapunov-based framework, in which we measure the distance of the solutions of the nonlinear power system model to the equilibrium manifold by analyzing the evolution

Ars, Technē, Śāstra, ʿIlm: What’s in a Name?

The designation of astrology as an art raises some simple but fundamentally im-portant historical questions. How old is this designation, and, given that earlier generations of astrologers wrote in different languages, what words did they use that we translate as ‘art’? What are the connotations of those different words in their historical contexts? What other designations than ‘art’ would have be

Association Between Vitamin D, Frailty, and Progression of Frailty in Community-Dwelling Older Women

CONTEXT: Vitamin D (25OHD) is involved in many physiological functions that decline with age, contributing to frailty and increased risk for negative health outcomes. Whether 25OHD is a long-term risk marker for frailty over a longer time and whether it is consistent with advancing age is unclear. OBJECTIVE: To investigate the association between 25OHD and frailty in older women followed for 10 ye

Suppressed natural killer cell activity in patients with chronic autoimmune thrombocytopenic purpura

Natural killer (NK) cell activity was studied in 17 patients with primary chronic idiopathic autoimmune thrombocytopenic purpura (ATP). Fifteen of 17 patients had a significantly reduced NK cytotoxicity against 51chromium labeled K562 target cells (mean LU20% = 18 ± 20 in patients versus 65 = 2 5 in controls, P < 0.001). NK activity was also significantly reduced in all of six patients with second

The metabolic syndrome - What is it and how should it be managed?

A cluster of metabolic factors have been merged into an entity named the metabolic syndrome. Although the characteristics of this syndrome have varied over time the presently used definition was established in 2009. The presence of three abnormal findings out of five components qualifies a person for the metabolic syndrome: elevated waist circumference, elevated triglycerides, reduced high-density

Effect of plasma-core-induced self-guiding on phase matching of high-order harmonic generation in gases

In this work, we numerically study a self-guiding process in which ionization plays a dominant role and analyze its effect on high-order harmonic generation (HHG) in gases. Although this type of self-guiding-termed "plasmacore- induced self-guiding" in previous works-limits the achievable cutoff by regulating the intensity of the laser beam, it provides favorable conditions for phase matching, whi

Citizen science in developing countries : how to improve volunteer participation

Citizen science is a powerful tool for connecting members of the public with research and for obtaining large amounts of data. However, it is far less commonly implemented in developing countries than in developed countries. We conducted a large-scale citizen-science program monitoring honey bee (Apis mellifera) colony losses in Argentina to examine how a national consortium composed of local coor

Professional judgements in collaboration

Although intimate partner violence is far from a new problem in society, it has lately gained increased attention both by governments and by the research community. In 2007, the Swedish government issued an action plan for “combating men’s violence against women, violence and oppression in the name of honour and violence in same-sex relationships” (2007/08:39), which included a call for increased

Development of 7-Item Perceived Meaning of Activity in Housing (PMA-H-7) to Assess Opportunities for Meaningful Activities in the Supported Housing Context for People With Psychiatric Disabilities

People with psychiatric disabilities need to be able to express their views about their support, for example, the provision of meaningful activity in supported accommodation. Brief scales may be necessary to avoid strain and discomfort for this group. The aim was to develop a brief version of Perceived Meaning in Activity—Housing (PMA-H) and investigate its factor structure, internal consistency,

The state of water in non-ionic surfactant solutions and lyotropic phases : Oxygen-17 magnetic relaxation study

Water 17O longitudinal and transverse relaxation rates have been measured in aqueous solutions and mesophases of the non-ionic alkyl oligo(ethylene oxide) surfactants C12En (n = 4, 5, 8) over wide ranges of temperature and concentration. In addition, two reference systems have been investigated: high molecular weight poly(ethylene oxide) and the dimer 1,2-dimethoxy ethane. The relaxation data are

Library Managers’ Use of Digital Technologies in Everyday Work Practices: : An Application of Human Activity Systems Modelling

As has been argued by systems thinking scholars, science and scientific thinking can be seen as socially constructed systems of institutionalized sets of activities through which systems thinking emerged. In this paper, the development of systems approaches is discussed to argue for the research approach adopted. Further, main concepts of systems thinking such as complexity, worldview, and human a