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Reduced Energy Expenditure and Impaired Feeding-Related Signals But Not High Energy Intake Reinforces Hypothalamic Obesity in Adults with Childhood Onset Craniopharyngioma.

Context: Obesity is a frequent manifestation of hypothalamic damage from a craniopharyngioma (CP). It is not yet clarified whether the obesity is due to alterations in energy expenditure, i.e. basal metabolic rate (BMR) and physical activity, or to increased energy intake (EI). Objective: The aim was to investigate whether energy expenditure and EI differed between childhood onset CP patients and

Improved label-free LC-MS analysis by wavelet-based noise rejection

Label-free LC-MS analysis allows determining the differential expression level of proteins in multiple samples, without the use of stable isotopes. This technique is based on the direct comparison of multiple runs, obtained by continuous detection in MS mode. Only differentially expressed peptides are selected for further fragmentation, thus avoiding the bias toward abundant peptides typical of da

A label-free nano-liquid chromatography-mass spectrometry approach for quantitative serum peptidomics in Crohn's disease patients.

The identification of serum biomarkers for the diagnosis of inflammatory bowel diseases able to reduce the need for invasive tests represents a major goal in their therapy and follow-up. We report here a methodological approach for the evaluation of specific changes in the serum peptides abundance in healthy (H) and Crohn's disease (CD) subjects, based on a label-free LC ESI/Q-TOF differential mas

Algeriet vid skiljevägen. Ett studium av politiska, ekonomiska och ideologiska strukturer i Algeriet 1992. Projektarbete för Försvarets Forskningsanstalt (FOA), juni – augusti 1992.

Algeriet vid skiljevägen. Ett studium av politiska, ekonomiska och ideologiska strukturer i Algeriet 1992. Projektarbete för Försvarets Forskningsanstalt (FOA), juni – augusti 1992. Torsten JansonKandidatstudent i islamologi, Lunds universitetSLUTSATSERAlgeriet 1992 - Point of no returnTvå saker om den algeriska nationen kan omedelbart konstateras: den är till sitt väsen en militärdiktatur; och de

Gender differences in subtypes of depression by first incidence and age of onset : a follow-up of the Lundby population

The Lundby Study is a prospective mental health survey in a community population (N = 3563), in which data were collected in 4 waves of field-work between 1947 and 1997. We investigated gender differences during the follow-up in overall first incidence rates, ages of onset, and incidence by age of onset patterns, in different subtypes of depression. The overall incidence rate in females was higher

Brief Admission Skåne (BAS), an intervention for indivi- duals with symptoms of borderline personality disorder, recurrent self-harm, at high risk for suicide. : Brief admission Skåne: Evaluation of fidelity to the method and individual-therapist experiences

Objectives: To measure treatment fidelity and to evaluate patient and clinician experiences with Brief Admission Skåne (BAS) over the pilot phase and first five months of the intervention phase of a randomized controlled trial (RCT) testing BAS. The purpose of the RCT is to determine whether BAS can reduce the frequency of acute psychiatric admissions for individuals with borderline personality di

Toy Consumption as Political : Challenges for Making Dreams Come True

This chapter looks at political consumerism in the toy sector, offering a brief history of consumer concerns and distinguishing among four strands of political consumerist research in this sector. A primary factor facilitating political consumerism of toys is that toy companies are extremely concerned about their reputation. Manufacturers cannot assume that parents and other carers do their usual

A sustainable working life for all ages – The swAge-model

The demographic shift is fast becoming a global challenge and an important public health concern. The proportion of people over 65 years is currently 10% around the world, but it is expected to rise to 22% by the year 2050 [1]. Populations ageing rapidly is widely seen as one of the most powerful transformative forces affecting society over the next four decades [1–4]. The ageing population is pro

Stellar abundance of binary stars : Their role in determining the formation location of super-earths and ice giants

Binary stars form from the same parent molecular cloud and thus have the same chemical composition. Forming planets take building material (solids) away from the surrounding protoplanetary disc. Assuming that the disc's accretion on to the star is the main process that clears the disc, the atmosphere of the star will show abundance reductions caused by the material accreted by the forming planet(s

Regulating recyclability under the ecodesign directive : How can we achieve synergies between waste and product policies for electric and electronic equipment to promote recycling?

Introduction: The interaction between different product policies will be crucial for the further advancement of a coherent product policy framework. The Commission has stated that ‘the complex and interlocking approach needed to build a resource-efficient Europe can only be achieved with a policy mix that optimizes synergies and addresses trade-offs between different areas and policies’. In the co

User privacy attitudes regarding proximity sensing

User attitudes on privacy with respect to location data has been extensively studied. However, user attitudes of privacy in relation to proximity sensing is still lacking. We present the results from a survey conducted on users of a proximity sensing application we developed and diffused by handing out phones with the proximity sensing application pre-installed, with 31 respondents. The results co

Electroweak phase transitions in multi-Higgs models : The case of Trinification-inspired THDSM

The rich vacuum structure of multi-Higgs extensions of the Standard Model (SM) may have interesting cosmological implications for the electroweak phase transition (EWPT). As an important example of such class of models, we consider a particularly simple low-energy SM-like limit of a recently proposed Grand-Unified Trinification model with the scalar sector composed of two Higgs doublets and a comp

Hermann Heller on Politics : Discipline, Sphere and Activity

Most students of politics are familiar with Carl Schmitt’s definition of politics as a friend-enemy distinction. Yet, only few know of alternative conceptions of politics in interwar Germany that emphasize cooperation and legality over confrontation and decisionism. To unlock such views, this article examines the work of Hermann Heller, a social-democratic constitutional theorist, and takes a clos

Managing a Century of Debt

This paper provides a consistent series for the Irish national debt since the foundation of the state. It also provides a continuous series for bond yields over the same period. The paper examines the factors behind the fluctuations in the debt burden over almost a century. The management of the debt burden by the Irish authorities has evolved over time, seeking to minimise both the burden on the

An experimental and kinetic modeling study on nitric oxide formation in premixed C3 alcohols flames

This study provides new quantitative NO concentrations measurements in n-propanol + air and i-propanol + air flames together with a new combustion kinetic model. The heat flux method was employed to stabilize propyl alcohols flames and the initial gas conditions were set to 323 K, 1 atm, and ϕ=0.7-1.4. Saturated laser-induced fluorescence was employed to measure NO concentration in the post-combus

In situ determination of N-2 broadening coefficients in flames for rotational CARS thermometry

Total N-2 S-branch broadening coefficients have been measured in situ as a function of radial position in a highly sooting ethylene diffusion flame by the use of time-resolved dual-broadband picosecond pure rotational CARS (RCARS). Time-domain measurements of the J-dependent N-2 rotational coherence decays in the flame were used to determine the broadening coefficients, and these coefficients were