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The effect of an α-2 receptor antagonist, idazoxan, on ischemic neuronal damage in the hippocampus and neocortex was studied in rats following 10 min of forebrain ischemia. Idazoxan was given 0.1 mg/kg i.v. immediately after recirculation, followed by 48 h of continuous infusion at a rate of 10 μg/kg/min. A histopathological examination of the CA1 region of the dorsal hippocampus and neocortex fro

Changes in the levels of arachidonic acid during ischemia in selectively vulnerable areas of the hippocampus were studied in the rat brain. Since neurons in the CA1 region are more vulnerable to ischemia than neurons in the adjacent CA3 region, the release of arachidonic acid in these two regions was measured during decapitation ischemia of 4- to 12-min duration. The concentration of free arachido

This study addresses the question of whether the cyclooxygenase inhibitors indomethacin and diclofenac and the glucocorticosteroid dexamethasone ameliorate neuronal necrosis following cerebral ischemia. In addition, since these drugs inhibit the production of prostaglandins and depress phospholipase A2 activity, respectively, the importance of free fatty acids (FFAs) on the development of ischemic

Lake Poopó is a terminal lake of the Bolivian Altiplano, with high salinity and heavy anthropogenic pollution from centuries of extensive mining activity. This study aims to describe how the water quality of groundwater and surface water system in different subwater-sheds of the Lake Poopó varies with geology and hydrology. Measurements of total dissolved solids (TDS) in wells show groundwater bec

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The most prominent poets in the two golden ages of Swedish Poetry in the 19th Century are presented: Tegnér, Stagnelius, von Heidenstam,Fröding, Karlfeldt. Their formal skills as well as their main themes are described, and citations are given in english and swedish.

In most of the industrial world the fractions of older people continuously increase (OECD, 2011). The upcoming demographic change is described as a threat to societal service. Many societies have to motivate people to work until an older age to increase the number of working hours in the economy (Eurostat, 2010). Factors important to whether older workers extend their working life are complex, mul

The surrounding climate gives temperature variations in both time and space for concrete structures. Due to external and internal restraints thermal strains and stresses may develop in the structure and these stresses can contribute to cracking. This will affect the performance of the structure. To predict the dynamic thermal conditions in concrete structures a finite element model has been develo