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Stretch of the vascular wall by the intraluminal blood pressure stimulates protein synthesis and contributes to the maintenance of the smooth muscle contractile phenotype. The expression of most smooth muscle specific genes has been shown to be regulated by serum response factor and stimulated by increased actin polymerization. Hence we hypothesized that stretch-induced differentiation is promoted
During the last decade research in the scientific domain of information systems (IS) in corporate mergers and acquisitions (M&As) has become increasingly popular. A not very surprising development regarding the significance of the empirical phenomenon of M&A and the importance of IS for modern business. However, the idea of IS playing an important role in M&As rests on assumptions, ane
Concerns regarding environmental issues such as greenhouse gas emissions and climate change have led to a shift within the research community and chemical and energy industry sectors for finding sustainable routes for producing fuels and chemicals from renewable resources, thereby minimizing our dependence on petroleum. The C3-chemical 3-hydroxypropionic acid has been identifed as a top candidate
Mice with allergically inflamed airways are widely used as animal models of asthma, but their relevance for human asthma is not understood. We, therefore, examined the time course of changes in respiratory input impedance during induced bronchoconstriction in BALB/c mice sensitized and challenged with ovalbumin. Our results indicate that bronchoconstriction in mice is accompanied by complete closu
Frontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions participants with clinical depression
The complement system is an essential effector of both innate and acquired immune responses. Due to its destructive potential, tight regulation is required. The contribution of complement has been associated with the pathogeneses in a wide range of diseases. In this thesis, aspects of complement activation were investigated in disorders characterized by thrombocytopenia.In papers I and II, clinica
In this thesis, a numerical approach is adopted to study biomass thermochemical conversion. Detailed physical and chemical processes involved in the thermochemical conversion of biomass are considered. The aims are to improve the understanding of the physical and chemical processes involved and to develop and validate mathematical models for numerical simulation of the biomass conversion process.
Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune processes and β-cell dysfunction are known to occur in type 1 diabetes, a complete understanding of the cell-to-cell interactions that support pancreatic function is still lacking. To characterize the pancreatic endocrine compartment, we stu
The aim of this study is to analyse how the study group method aids student entrepreneurs when developing entrepreneurial knowledge through the experiential learning process, and why it is important to stimulate peer learning in an experiential entrepreneurship education context. Due to a more experiential perspective on learning, the environment in which students learn, what students learn and wh
Lactone flavors with fruity, milky, coconut, and other aromas are widely used in the food and fragrance industries. Lactones are produced by chemical synthesis or by biotransformation of plant-sourced hydroxy fatty acids. We established a novel method to produce flavor lactones from abundant non-hydroxylated fatty acids using yeast cell factories. Oleaginous yeast Yarrowia lipolytica was engineere
The starch industry is a key sector of the European food industry with an annual turnover of approx. €4 billion. The production processes in the starch industry are still dominated by conventional separation processes such as evaporators, separators and rotary vacuum filters (RVFs). Membrane processes are only rarely used. This presentation will show how membrane processes can be used to optimise
AbstractUntil very recently, Germany belonged to the ‘familialist’ group of welfare states, which offered cash rather than services to married couples and families. Sweden, in contrast, belonged to the ‘non-familialist’ counterpart, fostering gender equality in employment and family care via public services and extended reconciliation measures for decades. During the 2000s, however, Germany eventu
Sivakumar et al. (2000a), by employing the correlation dimension method, provided preliminary evidence of the existence of chaos in the monthly rainfall-runoff process at the Göta basin in Sweden. The present study verifies and supports the earlier results and strengthens such evidence. The study analyses the monthly rainfall, runoff and runoff coefficient series using the nonlinear prediction met
Could the use of CSA practices stabilize the hunger crisis? Despite the general understanding that CSA practices increase farmers' food security, its resilience to climatic shocks is much less understood. To address this gap, this study analyzes the effect of three CSA practices: inorganic fertilization, intercropping and improved seeding on maize productivity in Ethiopia, Tanzania, and Uganda
