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Paper A investigates how to simulate a differentiated mean in cases where interchanging differentiation and expectation is not allowed. Three approaches are available, finite differences (FD's), infinitesimal perturbation analysis (IPA) and the likelihood ratio score function (LRSF) method. We study FD's under discontinuities and show that the optimal decay rate of the mean square error is typical
Popular Abstract in Swedish Åldrandet innebär fysiologiska förändringar i många olika organ t.ex hjärta, kärl och nervsystem. Även ämnesomsättning och behov av olika näringsämnen förändras, vilket innebär en ökad risk att drabbas av olika sjukdomstillstånd. Detta påverkar även den åldrande hjärnan som kan drabbas av mer eller mindre omfattande förändringar, i såväl blodkärl som nervceller. Mindre The aim of this study was to evaluate the diagnostic potentials of four different biochemical markers, serum cobalamin, blood folate, plasma homocysteine and serum methylmalonic acid for diagnosis of cobalamin/folate deficiency in a psychogeriatric population. The second aim was to investigate the relationship between these markers and various clinical and functional parameters of the nervous syst
A common denominator in most design literature is the goal of improving methods and techniques for the design process, thus contributing to increased efficiency of the design activities. It is a striking fact that the majority of the improvements suggested focus solely on qualitative methods and techniques, thereby neglecting to recognize the improvement potential inherent in quantitative methods
The production of ethyl esters (EE) from ethanol and cod-liver oil by an immobilised lipase in supercritical carbon dioxide (SCCO2) is described. This reaction results in a complex mixture of lipid components consisting of triglycerides, diglycerides, monoglycerides and ethyl esters. The primary goal has been to carry out enzymatic reaction and product separation simultaneously, by selectively ext
New Information Systems Development Methodologies (ISDMs) are suggested in the belief that their deployment would be beneficial to consultants in their work. A large number of ISDMs already exist but their value has been questioned and at the same time new methodologies continue to be introduced in an attempt to support and improve the practice of information systems development work. What is not
Uppsatsen behandlar kravet på tillräckliga kvalifikationer i 7 §, 22 §, 25 § och 25 a § LAS. Ur ett arbetsrättsligt perspektiv studeras vilka kvalifikationer arbetstagaren måste uppfylla för att åtnjuta rätten till omplacering respektive företräde. Rättspraxis spelar en stor roll i begreppstolkningen då lag och lagmotiv inte bidrar med någon definition av begreppet. I arbetet studeras även om, ochThe essay concerns the requirement of sufficient qualifications in 7 §, 22 §, 25 § och 25 a § LAS. From a labour law perspective the qualifications which the employee has to fulfil to enjoy the right to redeployment and precedence are studied. Case-law is an important source in the interpretation of the concept of sufficient qualifications since its' meaning is not defined by law or preparator
Skadelindringshierarkin är en vanligt föreslagen princip för att minska påverkan på naturkapital inom planprocesser. Skadelindringshierarkin innebär att påverkan på naturliga miljöer i första hand ska undvikas, annars minimeras – och när detta inte är möjligt återställas inom området eller kompenseras enligt en ekvivalens- och närhetsprincip. Beräkningarna kan utföras i en modell som exempelvis GrA commonly proposed principle for reducing impact on natural capital within the planning process is the mitigation hierarchy. The mitigation hierarchy means that impacts should primarily be avoided, otherwise minimized, and when this is not possible - restored or compensated according to an equivalency- and proximity principle. The outcome can be calculated in a model such as the Green Space Facto
Research article 2928 The Journal of Clinical Investigation http://www.jci.org Volume 122 Number 8 August 2012 Identification of embryonic stem cell–derived midbrain dopaminergic neurons for engraftment Yosif M. Ganat,1,2,3 Elizabeth L. Calder,1,2,3 Sonja Kriks,1,2 Jenny Nelander,4 Edmund Y. Tu,1,2,5 Fan Jia,6 Daniela Battista,1,7 Neil Harrison,6 Malin Parmar,4 Mark J. Tomishima,1,2,5 Urs Rutishau
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/jci58767.pdf - 2026-05-19
OVERVIEW: The article explains how Tetra Pak, a global manufacturing company, revamped its product development process (PDP) by transitioning from the traditional Stage-Gate model to a new innovative process that integrates Agile, Lean, Stage-Gate, the Scaled Agile Framework for enterprises (SAFe), and systems engineering methods. The design and implementation of the PDP at Tetra Pak offers insigh
ObjectivesPeople with serious illness approaching end of life often end up in emergency and hospital care, frequently against expressed preferences. Consequently, oncology trials record care days as a measure of treatment burden called “time toxicity.” However, this measure ignores the diminishing marginal utility of time: that the value of a day is higher when fewer remain. We aimed to incorporat
Antibiotic resistance poses a global threat. Antibiotics are administered to 80-90% of terminally ill patients but evidence of their effectiveness in improving survival or symptom relief at the end of life (EOL) is scarce. To determine the proportion of deceased patients that continue antibiotic treatment after documented EOL discussion and the decision to prioritise symptom relief over active tre
Popular Abstract in Swedish Spraytorkning är ett vanligt sätt att tillverka partiklar från en lösning. Genom att finfördela lösningen med hjälp av gas i ett spraymunstycke bildas miljontals små vätskedroppar, som blandas med varm torkgas i en torkkammare. Då avdunstar vätskan och fasta, torra partiklar bildas. Tekniken kan användas för att tillverka inhalationspartiklar för användning som läkemedeThe interest in spray drying for production of inhalable particles has grown considerably since the late 1980s. However, which process variables that control degradation and the solid state properties have not been subject to extensive research. This thesis deals with how important characteristics of inhalation particles can be controlled, i.e. particle size, morphology, degradation and crystalli
This report evaluates and compares the methods in fire inspection at Malmø Fire Brigade and Copenhagen Fire Brigade. The report also examines fire safety laws and regulations and the educational differences of the fire inspectors in Malmø and Copenhagen. The investigation is a project for Malmø Fire Brigade and Copenhagen Fire Brigade in co-operation with the Department of Fire Safety Engineering
Uppsatsen behandlar ämnet slöjförbud i Sverige. Syftet är att undersöka hur en svensk partipolitiskt obunden organisation, som arbetar med hedersrelaterat våld och förtryck, konstruerar deras ståndpunkter om slöjförbudet samt hur de tillförskriver attribut till slöjbärande kvinnor som kan bli påverkade av slöjförbud. Materialet består av en skrift från den slöjkritiska organisationen ”Glöm aldrig The subject in this thesis is ban of veils in Sweden. The aim of this thesis is to examine how a Swedish non-party political organization, that works with honor related violence and oppression, constructs their positions about a ban of the veil, and further how they prescribe attributes to veiled women who can be affected by the ban. The analyzed material is a publication from the Swedish veil-cri
Vår två delade problem frågeställning lyder som följer: Synliggör processen som vi beskriver med hjälp av teatermetaforen vilka aspekter som är bidragande till en kreativ process som leder till lärande? Kan vi följaktligen använda oss av den kreativa processen för att ge normativa bud på en förståelseform för organisationsbeteende? Vilken syftar till att lyfta fram vad som krävs av företagsledare
Torr jord ger ifrån sig mer koldioxid när det regnar När det regnar på torr jord bildas under en kort tid mycket mer koldioxid än vad jorden vanligtvis avger. Detta fenomen har varit känt sen 1950-talet och kallas enkelt för torkning och återfuktning. Även om vi vet att det sker så vet vi väldigt lite om varför det sker. Till en början trodde man att det hade att göra med en ökad aktivitet hos ma
Background Managing risk has become a crucial challenge for supply chain managers. In a complex supply chain, there are relations that have to be managed from the supplier’s supplier to the customer’s customer, and there is a lot of room for unforeseen challenges. The need to capture risk has for a long time been high, but due to the complexity of modern supply chains, uncertain developments are h
Dyspnea is a common and highly distressing symptom in patients with advanced illnesses. Many patients continue to experience chronic dyspnea despite optimal management of underlying disease(s) and various non-pharmacologic interventions, necessitating the consideration of pharmacologic therapies for palliation of dyspnea. One commonly asked question by clinicians is whether benzodiazepines have a
The aim of our thesis was to describe how the connection between co-dependent relatives and the alcohol-dependent influences the family into changes in their teamwork. Our purpose was also to answer the following questions: How is it living with an alcoholic? Are there any differences in how men and women feel and behave in their relationship with an alcoholic? Are factors like cultural belonging
