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Kursutvärdering Kurs: Biostatistisk grundkurs:MASB11 Utvärderas ocks̊a p̊a LTH: Nej Lärare: Ullrika Sahlin Antal studenter: 38 Svarsfrekvens: 15/38 Betyg: 15 VG, 11 G Sammanfattning: Studenterna verkar delvis nöjda. En del studenter tyckte att tempot p̊a föreläsningarna var för högt. Det fanns lite kommenterar kring att det var lite oklart vad som förväntades p̊a datorlaborationerna och

https://www.maths.lu.se/fileadmin/maths/utbildning_education/Kursutv_VT24/KU_Biostatistisk_grundkurs_MASB11_VT24.pdf - 2026-05-02

Dröjsmålstalan och EU-rätten – En undersökning av i vad mån förvaltningslagens dröjsmålstalan uppfyller unionsrättens krav på rättsskydd

Den 1 juli 2018 trädde den nya förvaltningslagen (2017:900) i kraft. I lagen ges enskilda, genom införandet av en dröjsmålstalan, för första gången i svensk förvaltningsrätt en generell rätt att föra talan mot förvaltningsmyndigheters passivitet. Om unionsrätten inte anger annat kommer den nya dröjsmålstalan, enligt principen om medlemsstaternas processuella autonomi, att tillämpas även vid förvalOn the first of July 2018, the new Swedish Administrative Procedure Act came into force. The Act introduces a new remedy against the inaction of administrative authorities (an action for failure to act, in Swedish “dröjsmålstalan”). Through the introduction of the new remedy, individuals are given a general right to appeal against the administrative authorities' inaction for the first time in

Supporterskap när arenan är utbytt mot Youtube : en fallstudie av livestreaming-fenomenet Watchalong

Livestreaming är ett medialt fenomen som idag finns tillgängligt för användare på plattformar såsom Facebook, Tiktok, Instagram och Youtube. Möjligheterna med en livestream är enorma och variationen i vad som kan anses vara innehåll för en livestream är lika stor. Innehållet som ligger i fokus i denna uppsats är ett fenomen som kallas för watchalong. En watchalong går ut på att en eller flera pers

Concomitant use of warfarin and ticagrelor as an alternative to triple antithrombotic therapy after an acute coronary syndrome.

Treatment with warfarin in combination with clopidogrel has been shown to reduce the incidence of major bleeding as compared to triple antithrombotic therapy (TT; warfarin, clopidogrel and aspirin). However, there are uncertainties regarding the risk for thrombosis since poor-responsiveness to clopidogrel is common. Ticagrelor is a more potent platelet inhibitor, but data supporting concurrent use

Pollen analytical and landscape reconstruction study at Lake Storsjön, southern Sweden, over the last 2000 years

This thesis reports the results from a pollen analytical and quantitative landscape reconstruction (REVEALS model) study in the drainage area of the Botorpsströmmen River in southern Sweden as a part of the project The archaeology and ecology of collapse: social and agricultural change following the Black Death and the project Managing Multiple Stressors in the Baltic Sea. The focus of this study

Reversing the Fuel-Electricity System Provides for Complete Fossil Fuel Replacement and a Stable Grid

As the total cost of renewable electricity falls lower than the price of fossil fuel, not only can electricity be used to replace fossil fuels using batteries in vehicles but it can also be used to produce fuels. This makes it possible to replace fuels in sectors not easily directly electrified. It also provides new ways of balancing the electricity system. When renewable electricity is cheap a lo

Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.

Wilms' tumor gene 1 (WT1) is a transcription factor involved in developmental processes. In adult hematopoiesis, only a small portion of early progenitor cells express WT1, whereas most leukemias show persistently high levels, suggesting an oncogenic role. We have previously characterized oncogenic BCR/ABL1 tyrosine kinase signaling pathways for increased WT1 expression. In this study, we show tha

A stakeholder participated system science based sustainable development indicator framework

The growing interest in sustainable development indicators (SDI) has resulted in the development and application of various SDI frameworks in the past two decades. Identification and selection of “right” indicators with such frameworks are essential, in the sense that, it is the information from these indicators that will help policy and decision makers to better understand the efficiency, effecti

High prevalence of type 2 diabetes in Iraqi and Swedish residents in a deprived Swedish neighbourhood - a population based study

Background: Immigrants from the Middle-East are at high risk of developing type 2 diabetes (T2D). The aim of the present survey was to measure, in a single deprived neighbourhood, the prevalence rates of impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and T2D in residents originating from Iraq and to compare them to those in residents born in Sweden. An additional aim was to ident

Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm that, if not treated, will progress into blast crisis (BC) of either myeloid or B lymphoid phenotype. The BCR-ABL1 fusion gene, encoding a constitutively active tyrosine kinase, is thought to be sufficient to cause chronic phase (CP) CML, whereas additional genetic lesions are needed for progression into CML BC. To generate a humanize

Dietary Fat Intake and Development of Specific Breast Cancer Subtypes.

We prospectively evaluated fat intake as predictor of developing breast cancer (BC) subtypes defined by estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 receptor (HER2), in a large (n = 337327) heterogeneous cohort of women, with 10062 BC case patients after 11.5 years, estimating BC hazard ratios (HRs) by Cox proportional hazard modeling. High total and satu

A New Look at Drugs Targeting Malignant Melanoma – An Application for Mass Spectrometry Imaging

Malignant melanoma (MM) patients are being treated with an increasing number of personalized medicine (PM) drugs, several of which are small molecule drugs developed to treat patients with specific disease genotypes and phenotypes. In particular, the clinical application of protein kinase inhibitors (PKI) has been highly effective for certain subsets of MM patients. Vemurafenib, a PKI targeting BR

Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.

Diamond-Blackfan anemia is a congenital erythroid hypoplasia caused by functional haploinsufficiency of genes encoding ribosomal proteins. Mutations involving the ribosomal protein S19 gene are detected in 25 % of patients. Enforced expression of ribosomal protein S19 improves the overall proliferative capacity, erythroid colony-forming potential and erythroid differentiation of hematopoietic prog

Absence of Epstein-Barr and Cytomegalovirus Infection in Neuroblastoma Cells by Standard Detection Methodologies.

Indications exist in the scientific literature that infection with human herpes family viruses may contribute to the pathogenesis of neuroblastoma (NB). However, systematic investigations regarding viral presence in NB cells have been scarcely reported. Here, the presence of DNA from Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) was assessed by PCR in 12 NBs, supplemented with RNA in s

Dietary intake of acrylamide and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort.

Background:Three prospective studies have evaluated the association between dietary acrylamide intake and endometrial cancer (EC) risk with inconsistent results. The objective of this study was to evaluate the association between acrylamide intake and EC risk: for overall EC, for type-I EC, and in never smokers and never users of oral contraceptives (OCs). Smoking is a source of acrylamide, and OC