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Effect of autoimmune diseases on risk and survival in female cancers.

OBJECTIVES: Patients with autoimmune (AI) diseases are diagnosed with increased frequencies of some cancers, which may depend on the underlying dysregulation of the immune system or treatment. Data on female cancers are limited. METHODS: We analyzed systematically risk and survival of female cancers of the breast, uterus, ovary and other genital organs in close to 200,000 patients diagnosed wi

A nationwide family study of pulmonary embolism: Identification of high risk families with increased risk of hospitalized and fatal pulmonary embolism.

BACKGROUND: Family history is an important risk factor for deep venous thrombosis. However, few studies have determined the importance of family history of pulmonary embolism (PE). OBJECTIVE: This nationwide study aimed to determine the familial risks of fatal and hospitalized PE. METHODS: The Swedish Multi-Generation Register for subjects aged 0 to 76years old born since 1932 were linked to t

Neighborhood deprivation and mortality in individuals with cancer: a multilevel analysis from Sweden.

Little information is available on the effect of neighborhood deprivation on mortality in individuals with cancer. The aim of this study was to investigate the effect of level of neighborhood deprivation on mortality after a wide range of cancer diagnoses. This 1990-2004 follow-up study included all individuals in Sweden aged 25-74 years and used multilevel logistic regression with individual-leve

Serum chlamydial lipopolysaccharide as a prognostic factor for a new cardiovascular event.

BACKGROUND: Infections caused by Chlamydia pneumoniae are considered to participate in inflammatory processes leading to coronary artery disease. After a primary infection, the bacteria remain dormant intracellularly causing a chronic inflammatory stimulus. MATERIALS AND METHODS: Blood samples were obtained from 235 patients with acute myocardial infarction (AMI) and 108 patients with unstable ang

Occupational Risk Factors for Systemic Lupus Erythematosus: a Nationwide Study Based on Hospitalizations in Sweden.

OBJECTIVE: To investigate possible associations between occupation and hospitalization for systemic lupus erythematosus (SLE) in a nationwide study. METHODS: A nationwide database was constructed in Sweden by linking the Swedish Census to the Hospital Discharge Register to obtain data on all first hospitalizations with a primary or secondary diagnosis of SLE in adults during the study period (19

Risk of coronary heart disease in patients with cancer: A nationwide follow-up study from Sweden.

BACKGROUND: Risk of coronary heart disease (CHD) in cancer patients has not been thoroughly investigated. The aim of the present study was to examine whether there is an association between cancer and first hospitalisation for CHD. METHODS: All individuals in Sweden with a diagnosis of cancer between 1st January 1987 and 31st December 2008 were followed for first hospitalisation for CHD. The refer

Neighbourhood socioeconomic status and coronary heart disease in individuals between 40 and 50 years.

OBJECTIVE: The incidence of myocardial infarction (MI) has decreased in general but not among younger middle-aged adults. We performed a cohort study of the association between neighbourhood socioeconomic status (SES) at the age of 40 and risk of MI before the age of 50 years. METHODS: All individuals in Sweden were included in the year of their 40th birthday, if it occurred between 1998 and 20

Depression or anxiety and all-cause mortality in adults with atrial fibrillation - A cohort study in Swedish primary care.

Objective Our aim was to study depression and anxiety in atrial fibrillation (AF) patients as risk factors for all-cause mortality in a primary care setting. Methods The study population included adults (n = 12 283) of 45 years and older diagnosed with AF in 75 primary care centres in Sweden. The association between depression or anxiety and all-cause mortality was explored using Cox regression an

Family history and risk of hospital treatment for varicose veins in Sweden.

Abstract BACKGROUND: Family history has been suggested as a risk factor for varicose veins, but recall bias may inflate the familial risks. The aim of this nationwide study was to determine familial risks for hospital treatment for varicose veins. METHODS: Data from the Swedish Multi-Generation Register of people aged 0-76 years were linked to Hospital Discharge Register data for 1964-2008. Stand

The risk of contralateral breast cancer in daughters of women with and without breast cancer.

We aimed to estimate the 15-year and lifetime risks of contralateral breast cancer in breast cancer patients according to the age of diagnosis of the first cancer and the history of breast cancer in the mother. The risks of contralateral breast cancer were estimated for all 78,775 breast cancer patients in the Swedish Family-Cancer Database (age at diagnosis of first breast cancer <70 years). The

Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers

BACKGROUND: Accumulating evidence suggests a relationship between endometrial cancer and ovarian cancer. Independent genome-wide association studies (GWAS) for endometrial cancer and ovarian cancer have identified 16 and 27 risk regions, respectively, four of which overlap between the two cancers. We aimed to identify joint endometrial and ovarian cancer risk loci by performing a meta-analysis of

Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis.

The ability to form biofilms is a crucial virulence trait for several microorganisms, including Klebsiella pneumoniae - a Gram-negative encapsulated bacterium often associated with nosocomial infections. It is estimated that 65-80% of bacterial infections are biofilm related. Biofilms are complex bacterial communities composed of one or more species encased in an extracellular matrix made of prot

Fire and sound reduction encapsulation of diesel engine

This Master thesis was conducted at ThyssenKrupp Marine Systems AB (TKMS AB), formerly known as Kockums AB. TKMS AB is based in Malmö, Sweden and is a manufacturer of conventionally powered submarines. The next generation of submarines, type A26, is currently under development and introduces many new features compared to prior submarine designs. Following increased fire and sound reduction demands

Grön offentlig entreprenadupphandling - I EU, Sverige och Lunds kommun

EU:s regelverk om offentlig upphandling uppdaterades 2014 och snart kommer uppdateringen i den svenska lagtexten. Det blir nu ännu tydligare att det är tillåtet att ställa miljökrav vid offentlig upphandling. Det är en vanlig uppfattning att det inte går att upphandla varor, tjänster och byggnadsverk med bättre miljöprestanda eftersom att de traditionellt sett inte kan konkurrera med kriteriet ”This is a master’s thesis about green public procurement (GPP) in the construction sector, based on a legal dogmathic study and a case study. The legal dogmathic part focused on both EU-legislation and on Swedish legislation. The case study was performed on the municipal of Lund to understand how a small authority works with GPP. The study of EU-legislation shows that the possibility to request b

Ty hon har visat stor kärlek: En narrativ studie över Luk 7:36-50

The title, “for she loved much”, stems from Luke 7:47. The aim of this essay is to interpret Luke 7:36-50 using the method of narrative criticism, since the structure and rhythm of the episode is similar to the structure of a novel. The purpose is to inquire into the issues of forgiveness by analyzing whether the sinful woman of the city was forgiven before or after approaching Jesus during the di

Förekomst av balanssvårigheter och försenad motorisk utveckling samt effekt av balansträning hos barn med senorineural hörselnedsättning: en litteraturstudie.

Sammanfattning Bakgrund: Sensorineural hörselnedsättning (SNHL) är en typ av hörselnedsättning där cochleans eller hörselnervens funktion är försämrad. I innerörat sitter balansorganet och hörselorganet i nära relation till varandra. Balans är en komplex funktion som uppstår av samspelet mellan individen, omgivningen och den uppgift som ska utföras. Barns motoriska utveckling är en åldersrelaterad