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From Medication to Education - People with autism in adult psychiatry

This dissertation concerns the field of applied psychiatry and focuses on the problems that are associated with the care and treatment of adult patients with autism spectrum disorders. The conditions that are described are valid for Swedish psychiatry and cannot be directly generalized to conditions outside of the country.

Dietary intake of heme iron and risk of gastric cancer in the European prospective investigation into cancer and nutrition study

Even though recent studies suggest that a high intake of heme iron is associated with several types of cancer, epidemiological studies in relation to gastric cancer (GC) are lacking. Our previous results show a positive association between red and processed meat and non cardia gastric cancer, especially in Helicobacter pylori infected subjects. The aim of the study is to investigate the associatio

Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification.

Appropriate regulation of hematopoietic stem cell (HSC) numbers and function is a requisite for life-long blood cell replenishment. Knowledge of factors that regulate HSC activity is derived largely from murine model systems, with serial transplantation often considered a "gold standard" to assess longevity and self-renewal of HSCs. In the literature, we noted inconsistencies in how serial transpl

EEG glasses for real-time brain electrical activity monitoring

Wearable devices are becoming a cornerstone for personalized and long-term health monitoring, enabling early intervention and data-driven medical decisions. In this work, we present e-Glass, a state-of-the-art smart wearable device that enables unobtrusive real-time electroencephalography (EEG) monitoring. Our evaluation shows that e-Glass adheres to the established international guidelines for cl

Gold impurity concentration in vapor-liquid-solid grown GaAs nanowires

Gold particles are commonly used as catalysts in the vapor-liquid-solid (VLS) growth of GaAs nanowires, but the incorporation of gold into the nanowires can negatively affect their electronic and optical properties. In this work, we investigate the equilibrium concentration of Au in GaAs nanowires using density functional theory calculations combined with thermodynamically assessed chemical potent

Advancing 90-day mortality and anastomotic leakage predictions after oesophagectomy for cancer using Explainable Artificial Intelligence

Introduction: Oesophageal resection carries significant morbidity and mortality. Artificial intelligence (AI) advances in medical research enable enhanced predictions, flexibility, and interpretability, especially for complex interactions and nonlinear relationships. Material and methods: We used a register-based case-control design nested within prospectively collected data from the Swedish Natio

An integrated Biobank in the Swedish Heart Failure Registry - clinomics, proteomics, transcriptomics and genomics

AIMS: To build a comprehensive biobank integrated in the Swedish Heart Failure Registry (SwedeHF) comprising comprehensive clinomic data, proteomic, transcriptomic and genomic information in combination with clinical and diagnostic characteristics and additional ICD-code registry data.METHODS: Blood and urine samples will be biobanked at SwedeHF registration with an optional second sampling after

LES of Stable Combustion and Lean Blow-out in a Mach 2 Cavity Flameeholder

This study presents high-fidelity Large Eddy Simulations (LES) of supersonic combustion in a Mach 2 cavity flameholder over the full stable fueling region from 40 to 200 slpm. The simulations employ Finite Rate Chemistry LES with the Z70 ethylene-air mechanism, the Localized Dynamic k-equation model, Partially Stirred Reactor turbulence-chemistry interaction model, conjugate heat transfer, and the

Prostate-specific antigen levels at age 60 and lifetime risk of lethal prostate cancer

INTRODUCTION: We investigated the natural history of the relationship between PSA at age 60 and lifetime risk of prostate cancer death in an unscreened cohort followed for 40 years, the Malmö Preventive Project. We also investigated whether percent free PSA could risk-stratify men with low PSAs.METHODS: The cohort included 1162 men aged 58-62 at blood draw in 1981-82, with 1151 deaths by December

Variations over time in proximal femoral strength in young adult men are not explained by areal bone mineral density alone

The decline in areal BMD (aBMD) in men may start as early as age 19, but it is debated whether proximal femoral strength follows the same pattern. We measured FN aBMD in a cross-sectional cohort of 1101 men aged 18-28 yr with two-dimensional DXA. Body height, weight, jump height, grip strength, and maximum knee extension torque muscle strength were measured with standard tests, after which BMI was

Monitoring Data for Anomaly Detection in Cloud-Based Systems : A Systematic Mapping Study

Context: Anomaly detection is crucial for maintaining cloud-based software systems, as it enables early identification and resolution of unexpected failures. Given rapid and significant advances in the anomaly detection domain and the complexity of its industrial implementation, an overview of techniques that utilize real-world operational data is needed. Aim: This study aims to complement existin

Captivating bimolecular photoredox dynamics of a ligand-to-metal charge transfer complex

Transition metal complexes featuring ligand-to-metal charge transfer (LMCT) excited states have been identified as promising candidates for driving electron transfer processes. To obtain an efficient system based on photo-induced bimolecular electron transfer, it is required that (1) photo-induced charge separation (CS) is faster than charge recombination (CR) of the separated charges, and (2) CR

Tvångslikvidation vid kapitalbrist - en komparativ studie

Bestämmelser om tvångslikvidation vid kapitalbrist har funnits i svensk aktiebolagsrätt sedan 1895 års ABL. Idag stadgas reglerna i 25 kap. 13-20§§ ABL. Det som fastslås i ABL skiljer sig från liknande stadgor i övriga Europa, detta är något som väcker frågor. Stadgandet i 25 kap. 13-20§§ ABL ställer upp åligganden för ett bolags styrelsemedlemmar. Dessa åligganden sanktioneras med ett personligThe provisions on compulsory winding-up due to capital shortage have been found in the Swedish corporate law since 1895. Today the rules are stipulated in Chapter 25, Section 13-20 in The Swedish Corporate Act (ABL). What is set in ABL differs from similar laws in other European countries and this raises some questions. The provisions in Chapter 25, Section 13-20 ABL sets up duties for the member

Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation.

Studies of developmental pathways of hematopoietic stem cells (HSCs) have defined lineage relationships throughout the blood system. This is relevant to acute myeloid leukemia (AML), where aggressiveness and therapeutic responsiveness can be influenced by the initial stage of transformation. To address this, we generated a mouse model in which the mixed-lineage leukemia/eleven-nineteen-leukemia (M

Laplace probability distributions and related stochastic processes

Skew Laplace distributions, which naturally arise in connection with random summation and quantile regression settings, offer an attractive and flexible alternative to the normal (Gaussian) distribution in a variety of settings where the assumptions of symmetry and short tail are too restrictive. The growing popularity of the Laplacebased models in recent years is due to their fundamental properti

Independent validation of four-dimensional flow MR velocities and vortex ring volume using particle imaging velocimetry and planar laser-Induced fluorescence. : Validation of 4D Flow using PIV and PLIF

PURPOSE:This study aimed to: (i) present and characterize a phantom setup for validation of four-dimensional (4D) flow using particle imaging velocimetry (PIV) and planar laser-induced fluorescence (PLIF); (ii) validate 4D flow velocity measurements using PIV; and (iii) validate 4D flow vortex ring volume (VV) using PLIF.METHODS:A pulsatile pump and a tank with a 25-mm nozzle were constructed. PIV

Inkludering eller Exkludering? Hantering av Spoilerproblematik vid Förhandlingsprocesser.

A great source of risk during peace processes of today comes from spoilers, individuals and groups who deliberately try to undermine every attempt to achieve a negotiated peace agreement. The aim of the thesis is to examine problems related to the management of spoilers during peace negotiations and the effects thereof. A central aspect in this respect is the dilemma of whether to include or exclu

Vägen ut : En kvalitativ intervjustudie om exitprocesser ut ur kommersiell sexuell exploatering

The way out - a qualitative interview study about the exiting processes out of prostitution The aim of this study was to examine the process of exiting prostitution. Our questions focused on what is needed for someone to exit prostitution and what support and treatment is desirable. The chosen method was qualitative semi-structured interviews with in total seven people of whom three had personal

Driving Sustainable Development Through Packaging - a Case Study at ASSA ABLOY

This master thesis investigates how a manufacturing company develops and implements packaging solutions for sustainable development, using ASSA ABLOY as a case study. Focusing on the sliding door operator produced at a manufacturing plant in Eastern Europe, the study explores the environmental and economic impacts of packaging throughout its life cycle and the internal packaging innovation process

Social Media Influencers Driving the Pre- Purchase Phase of the Consumer’s Decision-Making Process. A Comparison Between Hedonic and Utilitarian Products

The purpose of this research is to determine how social media influencers drive the pre-purchase phase of the consumer’s decision-making process and how these drivers differ in regard to hedonic and utilitarian products. Considering the aim to answer how the pre-purchase phase is driven through social media influencers’, and how the drivers differ for hedonic and utilitarian products, a qualitati