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Robe de Cour at the Swedish Court

The French court dress Le grand habit, worn at many European courts during the 18th century, was introduced in Sweden in the 1740’s by the crown princess Lovisa Ulrika, sister to Fredric II of Prussia. The robe de cour remained the official ceremonial dress for women at the Swedish court until Gustavus III launched the Swedish National Costume in 1778. The four robes de cour preserved in the Royal

Pre-operative plasma cell-free circulating tumor DNA and serum protein tumor markers as predictors of lung adenocarcinoma recurrence

Background: Lung cancer patients have a risk of recurrence even after curatively intended surgery. Cell-free circulating tumor DNA (ctDNA) and circulating tumor marker measurements are easily accessible through peripheral blood and could potentially identify patients with worse prognosis. The aim of this study was to examine ctDNA in pre-operative plasma and the role of tumor markers in pre-operat

Acoustic Enrichment of Extracellular Vesicles from Biological Fluids

Extracellular vesicles (EVs) have emerged as a rich source of biomarkers providing diagnostic and prognostic information in diseases such as cancer. Large-scale investigations into the contents of EVs in clinical cohorts are warranted, but a major obstacle is the lack of a rapid, reproducible, efficient, and low-cost methodology to enrich EVs. Here, we demonstrate the applicability of an automated

The one-third rule for PI controller tuning

Despite academic advances in PID controller design and development of automatic tuning procedures, there are still many PID controllers that are badly tuned, or not even tuned at all, in process industry. There are several reasons for this, but one major reason is that it is considered too time consuming to use current PID controller tuning methods. This paper presents a new tuning method that is

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover

Aims/hypothesisPPARGC1A encodes peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipocyte bi

Realism, Mechanism, Effect, and Comparative Contentious Politics

Charles Tilly was instrumental in launching the comparative study of contentious politics through key contributions delineating and defining the subject matter. But his input is epistemological as well as theoretical and substantive. What characterizes his epistemology is a realist mechanistic explanation rendering mechanisms tools of both explanation and comparison. Employing the realist perspect

Calculating Climate Debt. A Proposal

Abstract submitted to ISEE 2012 Theme: The Political Economy of Green Development By Rikard Warlenius PhD Candidate Human Ecology Division Lund University, Sweden 2011.11.24 Calculating Climate Debt. A Comparison and a Proposal The notion of climate debt has invoked widespread interest in the last few years. First conceptualized in 1999 within the Millennium movement for (financial) debt cancella

Why can't I sit with my friend ? The complexity in diverse anti-discriminatory practices in school.

The UN Convention on the Rights of the Child state that in all actions concerning children the best interests of the child shall be a primary consideration. Children are capable of forming their own views and have the right to express those views freely. The school plays an important role in empowering children in this socialization process and Swedish schools have in its educational assignment a

Precision medicine in complex diseases - : Molecular subgrouping for improved prediction and treatment stratification

Complex diseases are caused by a combination of genetic, lifestyle, and environmental factors and comprise common noncommunicable diseases, including allergies, cardiovascular disease, and psychiatric and metabolic disorders. More than 25% of Europeans suffer from a complex disease, and together these diseases account for 70% of all deaths. The use of genomic, molecular, or imaging data to develop

Autumn fueling behavior in passerines in relation to migratory distance and daylength

Songbirds have evolved diverse strategies to cope with seasonality, including long-, medium-, and short-distance migration. There is some evidence that birds with a longer migration distance deposit fuel faster. However, most studies focus on long-distance migrants. Comparisons between species with different migration distances are necessary to broaden our understanding of fueling capacity in migr

A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes

Obesity and type 2 diabetes are causally related, yet there is considerable heterogeneity in the consequences of both conditions and the mechanisms of action are poorly defined. Here we show a genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects. We annotate and then compare association signals for these profiles across clinical an

Timing rather than movement decisions explains age-related differences in wind support for a migratory bird

Migratory birds must make complex decisions to use wind to their advantage during flight and increasing flight performance is particularly important while crossing ecological barriers. Age-related differences in how birds deal with wind have suggested experience improves necessary skills in gaining positive wind support. However, differences in wind support between age groups over ecological barri