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Finite element analysis for simplified thermal dose planning in interstitial laser thermotherapy

The objective was to investigate if diffusing laser fibres can be modelled as conductive heat sources without miscalculating coagulated volumes, and if finite element analysis, disregarding light transport, may be used for three dimensional (3D) treatment planning in interstitial laser thermotherapy (ILT). Temperature distributions and coagulated volumes with a diffusing laser fibre, as compared t

The ICOS Atmosphere use case : From raw data to knowledge of societal relevance

In order to effectively tackle the on-going changes in global climate, stakeholders and policy makers across the globe need timely and accurate information they can trust on a wide range of topics. Here we briefly describe how observational data on greenhouse gas concentrations collected from the ICOS network of measurement stations in Europe is transformed via atmospheric modelling into informati

Objectively measured daily physical activity related to cardiac size in young children.

Training studies in children have suggested that endurance training can give enlargement of cardiac dimensions. This relationship has not been studied on a population-based level in young children with objective methods. A cross-sectional study was made of 248 children (140 boys and 108 girls), aged 8-11 years, from a population-based cohort. Left ventricular end-diastolic diameter (LVDD) and left

Spatial Temperature Differences in Portal Frame Bridges

Thermal actions are considered in the design of bridges, as temperature variations can lead to restraint stresses and subsequent cracking. However, load descriptions are in some cases oversimplified or incompatible with modern applications, and background studies are limited. This paper therefore aims to develop a more detailed load description for the load case describing temperature differences

The number of oocytes retrieved during IVF : A balance between efficacy and safety

STUDY QUESTION: What is the relationship between the number of oocytes collected in fresh IVF treatments and the likelihood of cumulative delivery rate (fresh and frozen) per oocyte aspiration, severe ovarian hyperstimulation syndrome (OHSS) and thromboembolic events? SUMMARY ANSWER: Cumulative delivery rate per aspiration increases up to 20 oocytes retrieved and then evens out while the incidence

Multi-Output Control of a Heavy Duty HCCI Engine Using Variable Valve Actuation and Model Predictive Control

Autoignition of a homogeneous mixture is very sensitive to operating conditions, therefore fast control is necessary for reliable operation. There exists several means to control the combustion phasing of an Homogeneous Charge Compression Ignition (HCCI) engine, but most of the presented controlled HCCI result has been performed with single-input single-output controllers. In order to fully operat

Influence of Triplet Surface Properties on Excited-State Deactivation of Expanded Cage Bis(tridentate)Ruthenium(II) Complexes

Calculations of excited-state potential energy surfaces (PESs) are useful to predict key properties relating to the deactivation cascade of transition-metal complexes. Here, we first perform full free optimizations of the relevant excited-state minima, followed by extensive two-dimensional PES calculations based on the minima of interest. Maps of the lowest triplet excited-state surfaces of two bi

Impact of systemic therapy on circulating leukocyte populations in patients with metastatic breast cancer

Tumors affect the immune system, locally and systemically. The frequencies of specific circulating immune cell populations correlate with disease progression as well as prognosis of the patients. Although largely neglected, conventional antitumoral therapies often possess immunomodulatory properties and affect the levels of specific immune cell populations. Most information, however, derive from a

Wideband RCS reduction based on a simple chessboard metasurface

To avoid being detected by radar, it is necessary to reduce stealthy military platforms' radar cross section (RCS). The operation of overlaying the metasurface (MS) on the targets is a good solution. A simple chessboard MS structure that can achieve low RCS over a large bandwidth is proposed. Only one unit cell is used to construct the MS. First, the unit cell working in 0.5 and 1−λ modes is desig

Flexible Density-based Multipath Component Clustering Utilizing Ground Truth Pose

Accurate statistical characterization of electromagnetic propagation is necessary for the design and deployment of radio systems. State-of-the-art channel models such as the Enhanced COST 2100 Channel Model utilize the concept of clusters of multipath components, and characterize channels by their inter- and intra-cluster statistics. Automatic clustering algorithms have been proposed in literature

Predicting the Functional Roles of Knee Joint Muscles from Internal Joint Moments

Introduction Knee muscles are commonly labeled as flexors or extensors and aptly stabilize the knee against sagittal plane loads. However, how these muscles stabilize the knee against adduction-abduction and rotational loads remains unclear. Our study sought 1) to classify muscle roles as they relate to joint stability by quantifying the relationship between individual muscle activation patterns a

Hygiene may attenuate selection for antibiotic resistance by changing microbial community structure

Good hygiene, in both health care and the community, is central to containing the rise of antibiotic resistance, as well as to infection control more generally. But despite the well-known importance, the ecological mechanisms by which hygiene (or other transmission control measures) affect the evolution of resistance remain to be elucidated. Using metacommunity ecology theory, we here propose that

An empirically based model of software prototyping : a mapping study and a multi-case study

Context: Prototyping is an established practice within product and user interface design that is also used as a requirements engineering (RE) practice within agile development. Even so, there is a lack of theory on prototyping.Aims: Our main research objective is to support practitioners in improving on their prototyping practices.Method: We have designed a model that describes key aspects of the

Software selection in large-scale software engineering: A model and criteria based on interactive rapid reviews

Context: Software selection in large-scale software development continues to be ad hoc and ill-structured. Previous proposals for software component selection tend to be technology-specific and/or do not consider business or ecosystem concerns.Objective: Our main aim is to develop an industrially relevant technology-agnostic method that can support practitioners in making informed decisions when s

High-Resolution Channel Sounding and Parameter Estimation in Multi-Site Cellular Networks

Understanding of electromagnetic propagation properties in real environments is necessary for efficient design and deployment of cellular systems. In this paper, we show a method to estimate high-resolution channel parameters with a massive antenna array in real network deployments. An antenna array mounted on a vehicle is used to receive downlink long-term evolution (LTE) reference signals from n

Extended FastSLAM Using Cellular Multipath Component Delays and Angular Information

Opportunistic navigation using cellular signals is appealing for scenarios where other navigation technologies face challenges. In this paper, long-term evolution (LTE) downlink signals from two neighboring commercial base stations (BS) are received by a massive antenna array mounted on a passenger vehicle. Multipath component (MPC) delays and angle-of-arrival (AOA) extracted from the received sig

Propagation Modeling for Physically Large Arrays: Measurements and Multipath Component Visibility

This paper deals with propagation and channel modeling for physically large arrays. The focus lies on acquiring a spatially consistent model, which is essential, especially for positioning and sensing applications. Ultra-wideband, synthetic array measurement data have been acquired with large positioning devices to support this research. We present a modified multipath channel model that accounts

EzSkiROS: A Case Study on Embedded Robotics DSLs to Catch Bugs Early

When we develop general-purpose robot software components, we rarely know the full context that they will execute in. This limits our ability to make predictions, including our ability to detect program bugs early. Since running a robot is an expensive task, finding errors at runtime can prolong the debugging loop or even cause safety hazards. In this paper, we propose an approach to help develope

Industry-academia collaboration for realism in software engineering research : Insights and recommendations

Context: Effective industry-academia collaboration may increase software engineering research relevance by increased realism, yet very challenging for reasons like confidentiality concerns, different objectives and priorities. Objective: We analyse industry-academia collaboration scenarios based on our own experiences as Ph.D. student and supervisor, and provide insights and recommendations to fac