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Turbulent fluxes make a substantial and growing contribution to the energy balance of ice surfaces globally, but are poorly constrained owing to challenges in estimating the aerodynamic roughness length (z0). Here, we used structure from motion (SfM) photogrammetry and terrestrial laser scanning (TLS) surveys to make plot-scale 2-D and 3-D microtopographic estimations of z0 and upscale these to ma
In this presentation, I continue previous work on extracting consequences for the design of integration policies from research on participatory sense-making in cognitive science. Participatory sense-making was introduced in cognitive science in the early 21st century. The idea, roughly, is that social understanding consists in mutually inclusive social face-to-face real-time participation in pursu
BackgroundCancer-associated fibroblasts (CAFs) comprise a heterogeneous population of stromal cells within the tumour microenvironment. CAFs exhibit both tumour-promoting and tumour-suppressing functions, making them exciting targets for improving cancer treatments. Careful isolation, identification, and characterisation of CAF heterogeneity is thus necessary for ex vivo validation and future impl
We consider efficient methods for the partitioned time-integration of multiphysics problems, which commonly exhibit a multiscale behavior, requiring independent time-grids. Examples are fluid structure interaction in e.g., the simulation of blood-flow or cooling of rocket engines, or ocean-atmosphere-vegetation interaction. The ideal method for solving these problems allows independent and adaptiv
Spatially-distributed values of glacier aerodynamic roughness (z0) are vital for robust estimates of turbulent energy fluxes and ice and snow melt. Microtopographic data allow rapid estimates of z0 over discrete plot-scale areas, but are sensitive to data scale and resolution. Here, we use an extensive multi-scale dataset from Hintereisferner, Austria, to develop a correction factor to derive z0 v
Aims: The role of resection remains debated in cases of metastatic gastric carcinoma (mGC). Some mGCs are technically resectable. At the population level, the real-world application of resection for mGC remains largely unclear in most Western countries. This large, population-based international investigation aimed to reveal the resection patterns and trends for mGC and the treatment-associated fa
Anthropogenic transformation of land globally is threatening water resources in terms of quality and availability. Managing water resources to ensure sustainable utilization is important for a semiarid country such as South Africa. Bayesian networks (BNs) are probabilistic graphical models that have been applied globally to a range of water resources management studies; however, there has been ver
Aerosol particles, small solid or liquid particles suspended in a gas, are found everywhere in the atmosphere. Air pollution from such particles, mainly soot from combustion-derived activity is a leading cause of premature deaths in the world and have a large effect on the climate. Aerosol particles can interact with climate-related processes in the atmosphere either directly by absorbing or refle
This paper documents the global climate model EC-Earth3-AerChem, one of the members of the EC-Earth3 family of models participating in the Coupled Model Intercomparison Project Phase 6 (CMIP6). EC-Earth3-AerChem has interactive aerosols and atmospheric chemistry and contributes to the Aerosols and Chemistry Model Intercomparison Project (AerChemMIP). In this paper, we give an overview of the model
The climate impact of deforestation depends on the relative strength of several biogeochemical and biogeophysical effects. In addition to affecting the exchange of carbon dioxide (CO2) and moisture with the atmosphere and surface albedo, vegetation emits biogenic volatile organic compounds (BVOCs) that alter the formation of short-lived climate forcers (SLCFs), which include aerosol, ozone and met
Many engineers and scientists prevalently use computational tools in electromagnetics, which is also the predominant case for antennas. The ever-increasing number of applications and technologies that employ antennas create a constant demand to improve and extend existing tools and develop new ones. This dissertation investigates computational tools for antenna analysis and design. Antenna current
Predictability of extreme changes in the Arctic Ocean freshwater content and the associated release into the subpolar North Atlantic up to one decade ahead is investigated using a CMIP5-type global climate model. The perfect-model setup consists of a 500 year control run, from which selected 10 year long segments are predicted by initialized, perturbed ensemble predictions. Initial conditions for
Background: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. Objectives: To determine the efficacy and safety of oral and sublingual immunotherapy in children and adults with immunoglobulin E (IgE)-mediated egg allergy as compared to a placebo treatmen
Intensification of arable crop production degrades soil health and production potential through loss of soil organic carbon. This, potentially, reduces agriculture's resilience to climate change and thus food security. Furthermore, the expected increase in frequency of adverse and extreme weather events due to climate change are likely to affect crop yields differently, depending on when in the gr
American bison (Bison bison L.) have recovered from the brink of extinction over the past century. Bison reintroduction creates multiple environmental benefits, but impacts on greenhouse gas emissions are poorly understood. Bison are thought to have produced some 2 Tg yr-1 of the estimated 9 15 Tg yr-1 of pre-industrial enteric methane emissions, but few measurements have been made due to their mo
As more people move to cities and urban areas are growing, demand for urban transport increases. This leads not only to pressure on sustainability and climate goals, but also on the attractiveness and liveability of urban areas. Thus, it is necessary to decrease the use of private cars and create a modal shift towards more sustainable modes of transport, such as walking, cycling and public transpo
Ischemic stroke is a leading cause of death and disability worldwide. Currently, there is no treatment that can promote recovery in the chronic phase. It has been shown that neurogenesis occurs in ischemic striatum in rodents and probably also in humans. Moreover, blood-borne macrophages have been found to enhance spontaneous post- stroke recovery in mice. These findings have suggested potentia
Important factors behind high levels of vulnerability and low adaptive capacity to climate variability and change in the developing world are direct reliance on natural resources, poverty and limited abilities to adapt financially and institutionally. In this study, focusing on the Lake Victoria Basin, a multitude of stressors on livelihoods, including climate related factors, are faced by the rur
Several aspects describing the state of the atmosphere in the North Sea region are considered in this chapter. These include large-scale circulation, means and extremes in temperature and precipitation, cyclones and winds, and radiation and clouds. The climate projections reveal several pronounced future changes in the state of the atmosphere in the North Sea region, both in the free atmosphere an
