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The bone marrow microenvironment provides indispensable factors to sustain blood production throughout life. It is also a hotspot for the progression of hematologic disorders and the most frequent site of solid tumor metastasis. Preclinical research relies on xenograft mouse models, but these models preclude the human-specific functional interactions of stem cells with their bone marrow microenvir

This open access book examines the conversations around gendered mental health in contemporary Western media culture. While early 21st century-media was marked by a distinct focus on happiness, productivity and success, during the 2010s negative feelings and discussions around mental health have become increasingly common in that same media landscape. This book traces this turn to sadness in womenExamines the discourse around female mental health in 21st century mediaIdentifies two conflicting aspects of mental illness awareness, profitable vulnerability and sad girl cultureTakes a feminist media studies approach to examine mental health in magazines and on social mediaThis open access book charts a brief history of gendered madness

Children and adolescents exposed to traumatic events are at high risk of developing posttraumatic stress disorder (PTSD). With the rare exception of very young children, their PTSD presentations at the symptom level are similar to those of trauma-exposed adults, as are their patterns of psychiatric comorbidity, particularly for adolescents. Untreated, at least a significant proportion will carry o

Förtal har, mot bakgrund av #metoo-rörelsens framväxt, fått ökad samhällelig uppmärksamhet. Främst kvinnor har blivit dömda för förtal i samband med offentliga uttalanden om upplevelser av sexuella övergrepp, där dem pekat ut en viss man som deras förövare. Offentliga uttalanden om en annans brotts-lighet eller förkastlighet, trots dess sanning, är kriminaliserat i Sverige. San-ningsbevisning tillDefamation has, in the context of the #metoo movement, received increased social attention. Mainly women, have been convicted of defamation in relation to public statements about experiences of sexual assault, in which they have identified a certain man as their perpetrator. Public statements about another´s criminality or reprehensibility, despite its truth, are criminalized in Sweden. Truth evid

Introduction Parkinson’s disease (PD) is a common neurodegenerative disease, which has extensive pathology that critically includes the loss of midbrain dopaminergic neurons. This loss leads to debilitating motor features such as bradykinesia and rigidity, as well as some non-motor symptoms. Intracerebral dopamine cell transplants have been explored for many years as a new approach to treating PD

The reassignment technique is used to increase localization for signal components in the time-frequency representation. The technique gives perfect localization for linear chirp signals and constant frequency signals. Despite the recent interest in using the reassignment technique to determine phase-shifts, no general expression of cross-spectrogram reassignment vectors exists. This submission aim

This study is part of a North West Europe (NWE) Interreg project called NWE-REGENERATIS that aims at the regeneration of past metallurgic sites and deposits through innovative circularity for raw materials. A novel geophysical methodology is developed to allow a 2D or 3D characterization of the recoverable metallic particles in terms of volume, type and grain sizes. We propose to integrate multi-m

This discussion paper recognizes that the Glasgow Consensus Statement is not optimally useful unless it is disseminated widely. Knowledge and use of the consensus statement and its call for centering humanism in healthcare extend to medical and health organizations and groups beyond the International Conference on Communication in Healthcare and Patient Education and Counseling audiences, to profe

Objective. Previous research has shown that elderly and disabled travelers using Special Transportation Services (STS) are injured without being involved in a vehicle crash. In order to estimate the true costs for these vehicle-related injuries, the focus needs to be adjusted towards an incident/traveler-oriented perspective. The aim of the project was thus to utilize such a perspective, in order

Abstract in UndeterminedCharacteristic of ecosystems is that different organisms can have similar functions and hence provide similar ecosystem services. Consequently functional diversity can maintain the rate of services despite environmental fluctuations. In this paper we present a method for estimating the resilience value of biodiversity. Central to a resilience perspective on biological conse

In this paper, we propose a new methodology for optimal memory mapping of data and instructions to Scratch-Pad Memories (SPM). In the mapping process, we optimize, as the main priority, the number of memory accesses to minimize power consumption. Minimization of external memory accesses lowers switching activity and therefore power consumption. The optimization is done by finding Pareto-points, us

In a recent paper we presented a procedure for optimal analyticalcontrol of several deformable mirrors based on only the measured guidestar wavefronts. The expected performance was evaluated for variousguide star configurations using up to three deformable mirrors. Forsimplicity the guide stars were assumed to be infinitely distant. Inthis paper we address the effect of using laser guide stars in

BACKGROUND: There is little consensus on a standard approach to analysing bone scan images. The Bone Scan Index (BSI) is predictive of survival in patients with progressive prostate cancer (PCa), but the popularity of this metric is hampered by the tedium of the manual calculation. OBJECTIVE: Develop a fully automated method of quantifying the BSI and determining the clinical value of automated

Arbetar samhällsviktiga verksamheter gemensamt för att hantera samhällets sårbarheter? När en händelse såsom då en storm sker, kan de allra flesta se hur sårbart samhället är och hur lätt ett problem hos en verksamhet snabbt sprider sig till andra verksamheter i samhället. Hur arbetar aktörer gemensamt för att hantera detta? Vi är många som har vaknat upp en morgon och sett att vägarna ligger vThe objective of this thesis is to provide answers to how a method can be designed to gain better knowledge of how collaboration looks between different critical societal activities in a preparing and preventive stage related to the management of transboundary risks. The designed method consists of two parts; a technique for data acquisition, and a method for data analysis. In order to evaluate th