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OBJECTIVES: Advanced glycation end product (AGE) is an established risk marker for diabetic vascular disease, and associated with the degree of diabetes complications, renal failure, and atherosclerosis in middle-aged and older individuals. The relationship between AGEs and aortic stiffness has not been thoroughly examined in the younger general population. We aimed to evaluate the association bet

In this work, we for the first time show that the geometrical magnetoresistance (gMR) effect is a powerful tool for extracting the carrier mobility in diffusive InGaAs near-surface quantum well MOSFETs. The technique shows excellent agreement to Hall effect measurements, confirming its validity. In addition, the gMR approach is less time-consuming, is suitable for measurements directly on the FETs

The catalytic oxidation of HCl by molecular oxygen (Deacon process) over ceria allows the recovery of molecular chlorine from the omnipresent HCl waste produced in various industrial processes. In previous density functional theory (DFT) model-calculations by Amrute et al. [ J. Catal. 2012, 286, 287−297.], it was proposed that the most critical reaction step in this process is the displacement of

High-acoustic-energy-density acoustofluidic devices are necessary to make this technology a viable option for clinical applications in the biomedical field. We present a mechanical interface that enables delivery of a high-amplitude acoustic field inside a fluid cavity by translating the vibrations from two large piezoelectric elements into a microfluidic chip. The study comprises both experimenta

Background: Despite known benefits of physical activity in reducing breast cancer risk, its impact on mammographic characteristics remain unclear and understudied. This study aimed to investigate associations between pre-diagnostic physical activity and mammographic features at breast cancer diagnosis, specifically mammographic breast density (MBD) and mammographic tumor appearance (MA), as well a

The Large Interferometer For Exoplanets (LIFE) is a proposed space mission that enables the spectral characterization of the thermal emission of exoplanets in the solar neighborhood. The mission is designed to search for global atmospheric biosignatures on dozens of temperate terrestrial exoplanets and it will naturally investigate the diversity of other worlds. Here, we review the status of the m

Background and aims: Normative values are lacking regarding intraepidermal nerve fiber density (IENFD) in thin sections of 5 µm. Thus, we aimed to assess IENFD in thin sections in a healthy adult population as well as to investigate whether IENFD is related to age, sex, and site of excision.Methods: Archival skin biopsies or excisions at the Department of Pathology, Lund, Sweden, from arm and leg

CONTEXT: As part of a broader institutional initiative, the serious illness care program was implemented in a multi-site academic primary care practice. After 2 years, a minority was observed to be documenting serious illness conversations routinely.OBJECTIVES: We aimed to learn about the motivations and actions of clinicians who routinely conducted and documented serious illness conversations.MET

Dwell time is crucial for railway operations, for example, 20% of the total travel time in a mass transit context in the Paris region. With this, it is also a source of delays due to its variability. One way to ensure the robustness of a timetable is to add margins as buffer time that can be consumed to absorb short delays. Much work has been done on run time margins, but dwell time margins receiv

Songbird migration involves frequent migratory flights interrupted by several days of stopover to refuel. For first-year migratory birds, this entails stopping in unfamiliar locations to exploit local resources and maximise fuelling rates. However, stopovers also pose mortality risks due to predator presence. We aimed to determine whether auditory cues from avian predators with differing hunting s

Objective: This study aimed to compare cumulative [fresh and frozen embryo transfers from one ovarian stimulation (OS) cycle] pregnancy and live birth rates in women for whom the choice between recombinant FSH (rFSH) and urinary FSH (uFSH) for OS was linked to FSH receptor (FSHR) N680S genotype and compared these to non-genotyped controls.Methods: To define the optimal combination of FSH type and

Two-dimensional neuronal cultures have a limited ability to recapitulate the in vivo environment of the brain. Here, we introduce a three-dimensional in vitro model for human glia-to-neuron conversion, surpassing the spatial and temporal constrains of two-dimensional cultures. Focused on direct conversion to induced dopamine neurons (iDANs) relevant to Parkinson disease, the model generates functi

Recent epidemiological studies have suggested a positive association between ultra-processed food consumption and breast cancer risk, although some studies also reported no association. Furthermore, the evidence regarding the associations between intake of food with lower degrees of processing and breast cancer risk is limited. Thus, we investigated the associations between dietary intake by degre

A high turnover among principals may disrupt the continuity of leadership and negativelyaffect teachers and, by extension, the students. The aim was to investigate to what extent variouswork environment factors and signs of exhaustion were associated with reported intentions tochange workplace among principals working in compulsory schools. A web-based questionnaire wasadministered twice, in 2018