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Biosensing using arrays of vertical semiconductor nanowires : mechanosensing and biomarker detection

Due to their high aspect ratio and increased surface-to-foot-print area, arrays of vertical semiconductor nanowires are used in numerous biological applications, such as cell transfection and biosensing. Here we focus on two specific valuable biosensing approaches that, so far, have received relatively limited attention in terms of their potential capabilities: cellular mechanosensing and lightgui

Jordbruk i Indien och Kina - En litteraturstudie om politik och fattigdom på landsbygden

Majoriteten av världens extremt fattiga bor i rurala områden och 300 miljoner av dem i Indien och Kina. Trots att länderna kommit en bit på vägen i sin strukturella omvandling arbetar fortfarande runt hälften av befolkningen på landsbygden inom jordbruket. De direkta och indirekta effekterna som den primära sektorn skapar har visat sig viktiga av olika anledningar. Hur detta kommer sig undersöks n

Ansvar för att skapa hållbarhet : en begreppsanalys av ansvar i den svenska modeindustrins hållbarhetsredovisningar

My thesis ’’Responsibility to create sustainability – a concept analysis of responsibility in the sustainability reports of the Swedish fashion industry’’, investigates Hennes & Mauritz and Filippa Ks view of the concept responsibility in sustainability reports, be- fore and after the adoption of The Sustainable development goals. The purpose of this study is to uncover if the enterprises view

Spela för att läsa! En studie om GraphoLearns effekter på avkodningsförmåga hos barn i åldrarna 6 till 7 år

Syfte: Huvudsyftet med studien var att undersöka den phonicsbaserade lärappen GraphoLearns effekter på avkodningsförmågan hos svensktalande barn i tidig läsutveckling. Sekundärt var syftet att undersöka huruvida träning med GraphoLearn kan påverka hjärnstruktur. Studien kan betraktas som en pilotstudie för ett större pågående projekt. Metod: Fjorton deltagare i åldrarna 6 till 7 år inkluderades. S

”Hjärtat slår och det känns som dom håller på att dö eller svimma” : en kvalitativ studie av hur lärare kan arbeta med talrädsla vid muntliga framställningar i svenskämnet i gymnasieskolan

I denna uppsats står rädsla för att tala i fokus. Talrädsla belyses med retorikämnet som grund, och studien tar avstamp i den svenska gymnasieskolan. Syftet med studien är att ta fram ett handfast material för hur svensklärare på gymnasieskolan kan arbeta med talrädda elever. För att uppnå syftet genomförs en litteraturstudie, där handböcker som behandlar området talrädsla studeras. I dessa handböIn this study, language anxiety is in focus. Language anxiety is studied with the subject of rhetoric as a basis, and the study is based on the Swedish upper secondary school. The aim of the study is to produce a solid material for how Swedish teachers at upper secondary school can work with students with language anxiety. In order to achieve this purpose, a literature study is carried out, in whi

Borta bra, hemma värst - En undersökning av det föreslagna barnfridsbrottet utifrån principer för kriminalisering

Våld i nära relationer och särskilt mäns våld mot kvinnor, anses idag utgöra ett allvarligt samhällsproblem. Det finns studier som visar att ungefär vart tionde barn i Sverige någon gång har upplevt våld mellan närstående vuxna. Detta kan få förödande konsekvenser för barnet i form av både fysiska och psykiska skador. Att låta barn bevittna våld eller andra brottsliga gärningar mellan närstående äViolence in close relationships and especially men’s violence against women, is today considered a social problem. There are studies showing that approximately every tenth child in Sweden has ever experienced violence between related adults. This can cause devastating consequences for a child, such as both physical and mental injuries. Letting children witness violence or other criminal acts betwe

All makt åt Tegnell - Vår befriare och förgörare

Sammanfattning Examensarbetes titel “All makt åt Tegnell - vår befriare och förgörare” - en kvalitativ dokumentstudie om följares konstruktioner av Anders Tegnell på Twitter Handledare Nadja Sörgärde Fem nyckelord Följare som konstruktörer av ledarskap, Anders Tegnell, Twitter, Kris och Attribution Forskningsfråga Hur framställs Anders Tegnell på Twitter? Syfte Syftet med denna studie är att

Kvinnlig rätt till nödvärn? En studie om nödvärnsrätt ur genusrättsligt perspektiv

En uppskattning på en fjärdedel av all våld som sker i nära relationer anmäls till polisen. Våld i nära relationer är komplex i sin natur som i sin tur orsakar ett omfattande mörkertal. Första gången en kvinna utsätts för våld tror hon att det är en engångsföreteelse. Efter ett antal upprepade våldshandlingar förskjuts hennes gränser och hennes verklighet cirkulerar kring mannens verklighet. Hon iAn estimate around a quarter of victims by domestic violence is reported to the police. Violence in intimate relationships has a complex nature that causes substantial number of unrecorded cases. The first time a woman is subjected to violence, she thinks it is a one-time occurrence. After a number of repeated acts of violence, her boundaries shift and her reality revolves around the man's rea

Experience a New Academic World: Chinese Female Students at Swedish Universities

This paper presents the outcomes of an applied cultural study carried out during spring semester 2010 with more than 10 Chinese female postgraduate students in Swedish universities. The aims of this research were to investigate Chinese female postgraduates’ decision-making process, to understand university lives in Sweden with the main focus on their learning experiences and social activities, and

Cell Replacement Therapy for Parkinson's Disease: Potential for Circuitry Repair

The derivation of dopamine neurons from human embryonic stem cells (hESCs) now offers a promising alternative to fetal tissue for cell replacement therapy (CRT) in Parkinson´s disease (PD). Using the appropriate chemical cues in vitro, hESCs can be patterned towards bona-fide ventral midbrain (VM) DA neurons that survive, reinnervate, release DA and provide functional recovery when transplanted in

Death of a Genre? : The Aesopic Fable and the Emergence of Modernity

Taking as its starting point the scholarly discussion about the possible death of the Aesopic fable towards the end of the eighteenth century, this article proposes a broadening of perspective, arguing for a thorough examination of the impact of modernity on some of the basic contexts and conditions of the genre. Four contextual factors are, subsequently, placed under scrutiny: the ethics of virtu

Convalescent plasma treatment in severely immunosuppressed patients hospitalized with COVID-19: an observational study of 28 cases

BackgroundImmunosuppressed patients are particularly vulnerable to severe infection from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), risking prolonged viremia and symptom duration. In this study we describe clinical and virological treatment outcomes in a heterogeneous group of patients with severe immunosuppression due to various causes suffering from COVID-19 infection, who

Fetal posterior cerebral artery configurations in an ischemic stroke versus an unselected hospital population

Background: Few MRA-based studies have systematically evaluated the prevalence and laterality of a fetal configuration of the posterior cerebral artery (FTP) in ischemic stroke populations versus other populations. This common variant is important in the setting of acute stroke and secondary prevention decisions. Objective: To determine the prevalence and laterality of FTP configurations in MRI-DW

BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia

BACKGROUND: We recently showed that striatal overexpression of brain derived neurotrophic factor (BDNF) by adeno-associated viral (AAV) vector exacerbated L-DOPA-induced dyskinesia (LID) in 6-OHDA-lesioned rats. An extensive sprouting of striatal serotonergic terminals accompanied this effect, accounting for the increased susceptibility to LID.OBJECTIVE: We set to investigate whether the BDNF effe

Mammographic density as an image-based biomarker of therapy response in neoadjuvant-treated breast cancer patients

Purpose: Personalized cancer treatment requires predictive biomarkers, including image-based biomarkers. Breast cancer (BC) patients receiving neoadjuvant chemotherapy (NACT) are in a clinically vulnerable situation with the tumor present. This study investigated whether mammographic density (MD), assessed pre-NACT, is predictive of pathological complete response (pCR). Methods: A total of 495 BC

Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries

BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain. METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 incide

Population specific annual cycles and migration strategies in a leap-frog migrant

A common migratory pattern in birds is that northerly breeding populations migrate to more southerly non-breeding sites compared to southerly breeding populations (leap-frog migration). Not only do populations experience differences in migration distances, but also different environmental conditions, which may vary spatiotemporally within their annual cycles, creating distinctive selective pressur

Clustering of blood cell count abnormalities and future risk of death

BACKGROUND: The identification of novel predictors of poor outcome may help stratify cardiovascular risk. Aim was to evaluate the individual contribution of blood cell count parameters, as well as their clustering, on the risk of death and cardiovascular events over the long term in the population-based Malmö Diet and Cancer Study cohort.METHODS: In 30,447 individuals (age 57 ± 8 years), we assess

Family history of breast cancer as a second primary malignancy in relatives : a nationwide cohort study

BACKGROUND: With the increasing number of breast cancer (BC) diagnosed as a second primary malignancy after a first primary non-breast cancer (BCa-2), it is unclear about the familial risk of BC among women with a first-degree relative (FDR, parents or siblings) affected by a BCa-2.METHODS: In this Swedish nationwide cohort study, 5315 women with a FDR affected by BCa-2 and 115,048 women with a FD