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Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplastic anemia, characterized by macrocytic anemia, reticulocytopenia, and severely reduced numbers of erythroid precursors in the bone marrow. For more than fifty years, glucocorticoids have remained the main option for pharmacological treatment of DBA. While continuous glucocorticoid administration increases hemoglobin levels in a major

AIM: Preterm birth is associated with a number of physical and mental health issues. The aim of this study was to find out if there was also any association between individuals born preterm in Sweden between 1984 and 2006 and the risk of unintentional injuries during childhood, adolescence and young adulthood METHODS: The study followed 2,297,134 individuals, including 5.9% born preterm, from 1985

Coronary heart disease (CHD) development is associated to a combination of lifestyle and genetic factors. A number of lifestyle risk factors is well defined, while genetic factors have not yet been well determined.

När en väljare röstar med andras beteende i åtanke och politikutfall i sikte är det en "strategisk" röst. Den här studien relaterar väljares strategiska överväganden till olika steg i regeringsbildningsprocessen: att ta plats i parlamentet, ingå i regering, och påverka politikutfallet. Detta innebär att väljaren ibland tänker som ett parti på vad rösten kan få för konsekvenser. Utifrån detta perspIf a voter defects from preference under the consideration of policy outcomes and others' behavior, it is a "strategic vote". This thesis relates voters' strategic considerations to the government formation process: the chances for a party to gain seats, enter office, and affect overall policies. This implies that voters sometimes think like parties on the governmental consequences of the vote. Fr

Genetic risk scores (GRSs) have been associated with coronary heart disease (CHD) in large studies. We asked whether expanding an established 27-variant GRS (GRS27) to a 50-variant GRS (GRS50) improved CHD prediction and whether GRSs are independent of self-reported family history of CHD.

We investigated causal effect of completed growth, measured by adult height, on coronary heart disease (CHD), stroke and cardiovascular traits, using instrumental variable (IV) Mendelian randomization meta-analysis.

Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with r

BACKGROUND:: Exposure to second-hand smoke has been shown to be associated with increased cardiovascular mortality in several, but not all, epidemiologic studies. Our aim was to investigate the risk of circulatory death associated with exposure to second-hand smoke in never-smokers in a very large prospective study, the European Prospective Investigation into Cancer and Nutrition. A secondary aim

The purpose of the thesis is to examine to what extent former high ranking state officials are immune for international crimes before foreign national courts. Historically national courts have recognized absolute immunity, but this approach has gradually to some extent changed after the establishment of international tribunals and the International Criminal Court in which official capacity is irre

The nomadic pastoralists of the Sahel are often identified as a group at the frontline of global climate change. Their existence in arid and semi-arid regions and their reliance on seasonal rainfall are among the factors that contribute to their vulnerability to drought and climate shocks. This study focuses on risks to pastoralists in Sudan, asking whether index-based livestock insurance, an innoPastoralism is a nomadic lifestyle and a livelihood system that revolves around raising livestock. By migrating seasonally in search of water and pasture for their animals, pastoralists are able to inhabit and make productive use some of the world’s harshest environments. In Sudan, where over 90% of the vast land area is covered by desert and drylands, pastoralism remains a vital feature of the co

Asfalt är den vanligaste vägbeläggningstypen i Sverige. Asfalt består av bitumen, filler, sten-material och eventuella tillsatser. Stenmaterialet utgör huvuddelen av asfaltmassan och ska ta upp trafiklasterna. När bitumen blandas med filler bildar det ett asfaltbruk som binder samman stenmaterialet till en beläggning. En väsentlig del för beläggningen är att den har rätt egen-skaper för det avseddThe Master Thesis was set to study the possibility to measure the rheological properties of bitumen-filler mastic with RVB (Rotational Viscometer type Brookfield) and DSR (Dy-namic Shear Rheometer). This was carried out with an initial study, with promising results, from the RVB. It is known that filler has a stiffening effect when mixed with bitumen (FAS Method 253-02) and this was also confirmed

The focus of my thesis has been the Swedish lay judges. My purpose has been to examine the Swedish system of lay judges and furthermore study it in relation to legal certainty. My major problem statement has been: In accordance with legal certainty, what advantages and disadvantages can be seen with the system of lay judges? The Swedish lay judges participate primarily in district and appellate c

Våld i nära relationer och särskilt mäns våld mot kvinnor, anses idag utgöra ett allvarligt samhällsproblem. Det finns studier som visar att ungefär vart tionde barn i Sverige någon gång har upplevt våld mellan närstående vuxna. Detta kan få förödande konsekvenser för barnet i form av både fysiska och psykiska skador. Att låta barn bevittna våld eller andra brottsliga gärningar mellan närstående äViolence in close relationships and especially men’s violence against women, is today considered a social problem. There are studies showing that approximately every tenth child in Sweden has ever experienced violence between related adults. This can cause devastating consequences for a child, such as both physical and mental injuries. Letting children witness violence or other criminal acts betwe

Sammanfattning Examensarbetes titel “All makt åt Tegnell - vår befriare och förgörare” - en kvalitativ dokumentstudie om följares konstruktioner av Anders Tegnell på Twitter Handledare Nadja Sörgärde Fem nyckelord Följare som konstruktörer av ledarskap, Anders Tegnell, Twitter, Kris och Attribution Forskningsfråga Hur framställs Anders Tegnell på Twitter? Syfte Syftet med denna studie är att

Denna uppsats handlar om den delen av kvinnorörelsens historia där kvinnors rätt till högre statstjänster berörs. I takt med industrialiseringen förändrades det svenska samhället och medförde att kvinnor tog plats på arbetsmarknaden på ett helt annat sätt än tidigare. Sedan mitten av 1800-talet var kvinnor aktiva på den statliga arbetsmarknaden och fick tillträde till universitetsstudier i början This essay is about the part of the history of the women's movement where women's right to higher civil service is affected. In time as the industrialization happened, Swedish society changed which resulted in that women took their place in the labor market in a completely different way than before. Since the middle of the 19th century, women were active in the state labor market and gaine

My thesis ’’Responsibility to create sustainability – a concept analysis of responsibility in the sustainability reports of the Swedish fashion industry’’, investigates Hennes & Mauritz and Filippa Ks view of the concept responsibility in sustainability reports, be- fore and after the adoption of The Sustainable development goals. The purpose of this study is to uncover if the enterprises view

Syfte: Huvudsyftet med studien var att undersöka den phonicsbaserade lärappen GraphoLearns effekter på avkodningsförmågan hos svensktalande barn i tidig läsutveckling. Sekundärt var syftet att undersöka huruvida träning med GraphoLearn kan påverka hjärnstruktur. Studien kan betraktas som en pilotstudie för ett större pågående projekt. Metod: Fjorton deltagare i åldrarna 6 till 7 år inkluderades. S