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Traffic safety is a complex and important research area with the potential to save many lives in the future. Two key problems are considered, namely the gathering of reliable and detailed road user statistics which can be used to estimate the safety of a traffic environment and taking advantage of surveillance infrastructure to guide and assist vehicles in real time, primarily autonomous ones. A c
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Abstract in ItalianQuesta esposizione propone in maniera teoretica una critica dell’esagerazione come approccio utile a qualsiasi filosofia che si occupi dei cosiddetti temi esistenziali. Si segue l’esempio dell’esagerazione per proporre un pensare oltre l’essere, in contrasto con la questione dell’essere senza esagerazione. Infine, si propone la critica propria dell’esagerazione come atteggiamentThis theoretical exposition proposes the critique of exaggeration as the approach to any philosophy that deals with the so-called existential themes. It provides the example of exaggeration in thinking beyond being in contrast to the question of being without exaggeration. Finally, it proposes the critique of exaggeration as a philosophical attitude that resists the temptation to seriously engage
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Background: Sick leave due to stress-related mental ill health increases in society. In occupational therapy, occupational balance is considered important for experiencing health and well-being. Thus, knowledge regarding occupational balance and occupational value constitute essential parts of occupational therapists’ work with people suffering from occupational ill health. Objective: The aim of t
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The least absolute shrinkage and selection operator (LASSO) algorithm is a promising method for sparse source location in time–division multiplexing (TDM) multiple–input, multiple– output (MIMO) radar systems, with notable performance gains in regard to resolution enhancement and side lobe suppression. However, the current batch LASSO algorithm suffers from high– computational complexity when deal
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The use of molecular data to study the evolutionary history of organisms has revolutionized the field of systematics. Now with the appearance of high throughput sequencing (HTS) technologies, more and more genetic sequence data are available. One of the important sources of genetic data for phylogenetic analyses has been mitochondrial DNA. The limitations of mitochondrial DNA for the study of phyl
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Propionic acid (PA) is a naturally occurring short chain fatty acid produced by microbial fermentation of the indigestible foods in the intestine, having a positive effect on the gastrointestinal health. PA inhibits the growth of pathogenic bacteria and molds; hence it is widely used as preservative for food, feed and grains. It is also used as a component in several industrial products like polym
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Background: High-throughput sequencing often provides a foundation for experimental analyses in the life sciences. For many such methods, an intermediate layer of bioinformatics data analysis is the genomic signal track constructed by short read mapping to a particular genome assembly. There are many software tools to visualize genomic tracks in a web browser or with a stand-alone graphical user i
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Background: Existing working heart models for ex vivo functional evaluation of donor hearts often use cardiac afterloads made up of discrete resistive and compliant elements. This approach limits the practicality of independently controlling systolic and diastolic aortic pressure to safely test the heart under multiple loading conditions. We present and investigate a novel afterload concept design
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Impairment of normal hematopoiesis and leukemia progression are 2 well-linked processes during leukemia development and are controlled by the bone marrow (BM) niche. Extracellular matrix proteins, including laminin, are important BM niche components. However, their role in hematopoiesis regeneration and leukemia is unknown. Laminin α4 (Lama4), a major receptor-binding chain of several laminins, is
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Objectives: The primary objective was to investigate the utility of blood-basedbiomarkers of amyloid, tau, and neurodegeneration for (i) screening, (ii)enrichment, and (iii) tracking response to treatment in clinical trials of Alzheimer’sdisease.Methods: Longitudinal, participant-level data used in these studies was drawn fromthe Swedish BioFINDER study and the ADNI study. Participants were classi
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Purpose: Accuracy investigation of volumetric navigators for motion correction, with emphasis on geometric EPI distortions at ultrahigh field. Methods: High-resolution Dixon images were collected in different head positions and reconstructed to water, fat, T2*, and B0 maps. Resolution reduction was performed, and the T2* and B0 maps were used to apply effects of TE and EPI distortions to simulate
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Radiative transfer (RT) is a key component for investigating atmospheres of planetary bodies. With the 3D nature of exoplanet atmospheres being important in giving rise to their observable properties, accurate and fast 3D methods are required to be developed to meet future multidimensional and temporal data sets. We develop an open-source GPU RT code, gCMCRT, a Monte Carlo RT forward model for gen
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Organic electrochemical transistors formed by in operando electropolymerization of the semiconducting channel are increasingly becoming recognized as a simple and effective implementation of synapses in neuromorphic hardware. However, very few studies have reported the requirements that must be met to ensure that the polymer spreads along the substrate to form a functional conducting channel. The
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The performance of structural timber connections is of utmost importance since they control the global response of the building. A ductile failure mechanism on the global scale is desirable, especially in the design of structures in seismic areas, where dissipative components in which ductile failure modes need to be ensured are considered. Therefore, the knowledge of possible brittle failure mode
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This paper presents a two-stage procedure to create a surface integrity predictor. The first stage includes data clustering, which allows to evaluate the achievable surface quality. The second stage consists in training the model to predict which cluster the machined surface will belong to. To demonstrate the applicability, an experimental plan for machining of Inconel 718 in milling was developed
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Contemporary hybrid zones act as natural laboratories for the investigation of species boundaries and may shed light on the little understood roles of sex chromosomes in species divergence. Sex chromosomes are considered to function as a hotspot of genetic divergence between species; indicated by less genomic introgression compared to autosomes during hybridization. Moreover, they are thought to c
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We conducted an extensive geophysical field campaign using ground-penetrating radar (GPR) and electrical resistivity tomography (ERT) in a former military area at the archaeological site of Nora (South-Western Sardinia). The purpose was to identify a Phoenician, and then Punic and Roman, necropolis of considerable interest, subject of a long-term investigation and currently under excavation. In th
