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Background: Alcohol intake increases recurrence of atrial fibrillation (AF), but its relationship with cardiovascular outcomes is less well characterized. We aimed to study the association between different levels of alcohol intake and cardiovascular outcomes in a global cohort of patients with AF. Methods: This is a cross-sectional analysis of the RE-LY AF registry, including 15,400 patients with

Objectives To study the prevalence of and interplay between common neuropsychiatric sequelae 3-4 years after onset of first-ever stroke - specifically post-stroke fatigue (PSF), post-stroke depression (PSD) and post-stroke cognitive impairment (PSCI). Design Population-based cohort study. Setting Catchment area of a Swedish University Hospital. Participants We recruited individuals with first-ever

Fire retardants are extensively used to reduce the flammability (combustibility) of wood–based construction materials in an effort to improve fire safety of buildings. However, little is known of the composition and potential risks to human health of smoke emissions produced from combustion of fire retardant treated wood. To help understand the risk to human health, fire smoke emissions produced f

Background/Objectives: Worldwide, men experience a higher incidence of pancreatic cancer (PC) than women. Methods: To increase understanding of the underlying reasons for this sex-related difference, we analysed general and sex-related risk factors for PC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort (women/men No. = 293,682/136,728; 717/577 PC-cases). Results:

Public health can be immediately and substantially improved by policies that also mitigate climate change over the longer term. However, implementation of these policies has been slowed at least in part by doubts and lack of awareness of these health co-benefits. To address this barrier to progress, we demonstrate how an illustrative set of interventions led to environmental, health, and economic

Background Colorectal polypectomy is operator dependent, with variable rates of complete resection. The currently available assessment tools do not provide specific competency-based evaluation of provider technique. We aimed to validate the Global Polypectomy Assessment Tool (GPAT), a novel competency assessment tool for colorectal polypectomy. Methods GPAT was derived from the ESGE Curriculum for

Aims: Economic simulation models, such as the IHE Type 2 Diabetes Cohort Model (IHE-DCM-T2), are used widely to inform resource allocation for Type 2 Diabetes (T2D) treatments. Recently, IHE-DCM-T2 was augmented with Japanese-specific risk equations to align with the Japanese healthcare context. This study extends prior model validation of IHE-DCM-T2 to cover the Japanese risk equations for applic

Objective: To identify predictors of GCA in patients with PMR. Methods: Patients with PMR were identified among participants in two population-based health surveys. Those with a registered diagnosis indicating PMR in national and regional registers (the latter including primary care) were included. Medical records from hospitals and primary care were systematically reviewed. PMR diagnoses were ver

Objective To compare neurodevelopmental outcomes in extremely preterm (EPT) children born across two epochs in Sweden. Design and setting Nationwide population-based cohorts of infants born at 22–26 weeks’ gestation in 2004–2007 (Cohort 1) and 2014–2016 (Cohort 2), comprising 1606 live births. Survivors were assessed at 2–2.5 years’ corrected age using the same protocol design. Main outcome The pr

Objective: This study aimed to describe the regional, population-based, organised prostate cancer testing (OPT) programmes that are being introduced throughout Sweden: motives, structure, target population, diagnostic algorithm, quality control, outcomes, research, and future perspectives. Results: In 2018, the Swedish National Board of Health and Welfare renewed their recommendation against scree

BACKGROUND: Dupuytren disease (DD) is a benign fibroproliferative disorder affecting the hand. Although diabetes mellitus is a known risk factor, the underlying mechanisms behind this association remain unclear. This study aimed to examine the relationship between glycemic control and DD in type 1 (T1D) and type 2 diabetes (T2D), and to identify other metabolic risk factors influencing DD risk.MET

Introduction: A core element of caring science, is for caregivers to understand and collaborate with patients. Previous research shows that women receiving forensic psychiatric care evoke strong emotions among caregivers, but there is little research on the subject, and increased knowledge about caregivers’ experiences of providing care for female patients in forensic psychiatry, and of balancing

BACKGROUND: – Proteins linked to heritable coronary heart disease (CHD) could uncover new pathophysiological mechanisms of atherosclerosis. We report on the protein profile associated with a family history of early-onset CHD and whether the relation between proteins and coronary atherosclerotic burden differs according to family history status, as well as inferences from Mendelian randomization. M