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Off-axis multilayer zone plate with 16 nm × 28 nm focus for high-resolution X-ray beam induced current imaging

Using multilayer zone plates (MZPs) as two-dimensional optics, focal spot sizes of less than 10 nm can be achieved, as we show here with a focus of 8.4 nm × 9.6 nm, but the need for order-sorting apertures prohibits practical working distances. To overcome this issue, here an off-axis illumination of a circular MZP is introduced to trade off between working distance and focal spot size. By this, t

In situ measurements of oxidation–reduction potential and hydrogen peroxide concentration as tools for revealing LPMO inactivation during enzymatic saccharification of cellulose

Background: Biochemical conversion of lignocellulosic biomass to simple sugars at commercial scale is hampered by the high cost of saccharifying enzymes. Lytic polysaccharide monooxygenases (LPMOs) may hold the key to overcome economic barriers. Recent studies have shown that controlled activation of LPMOs by a continuous H2O2 supply can boost saccharification yields, while overdosing H2O2 may lea

Small area influences on the individual unhealthy lifestyle behaviors : A multilevel analysis of discriminatory accuracy

We estimated the discriminatory power of area of residence (census tract) on the prevalence of main risk factors for chronic diseases. Results, based on a sample of 21,007 participants from the 2011–2012 National Health Survey of Spain, show a differential influence of the geosocial environment on the four health risk factors. Accounting for census tracts substantially increases the discriminatory

Inflammatory depression—mechanisms and non-pharmacological interventions

Treatment of depression is hampered by the failure to identify distinct symptom profiles with distinct pathophysiologies that differentially respond to distinct treatments. We posit that inflammatory depression is a meaningful depression subtype associated with specific symptoms and biological abnormalities. We review several upstream, potentially causative, mechanisms driving low-grade inflammati

Association between circulating furin levels, obesity and pro-inflammatory markers in children

Aim: To, in children, investigate the associations between serum furin, obesity, overweight, body fat and circulating markers reflecting adipose tissue or systemic inflammation. Methods: We analysed furin, leptin, adipocyte fatty acid–binding protein, triglycerides, interleukin (IL)-6, IL-8 and C-reactive protein in serum from 166 children in the Pediatric Osteoporosis Prevention (POP) study colle

Excitations in the Ultimate Quantum Fluid

Researchers have measured superfluid helium’s full dispersion spectrum, explaining discrepancies in previous studies and constraining theories of superfluidity.

Magnetic microphase inhomogeneity as a thermodynamic precursor of ground-state phase separation in weakly coupled spin-3/2 chains

γ-CoV2O6 is a quasi-one-dimensional spin-3/2 magnet that possesses two distinct magnetic orders at low temperatures with propagation vectors k1=(½,0,0) and k2=(¼ + δh, δk, - ¼ + δl), respectively. Here we use muon spin relaxation and rotation to reveal the thermodynamics of the magnetic phase separation in this compound. In the paramagnetic (PM) region, short-range correlated spin clusters emerge

A snapshot review—Fluctuations in quantum materials: from skyrmions to superconductivity

By measuring a linear response function directly, such as the dynamic susceptibility, one can understand fundamental material properties. However, a fresh perspective can be offered by studying fluctuations. This can be related back to the dynamic susceptibility through the fluctuation–dissipation theorem, which relates the fluctuations in a system to its response, an alternate route to access the

Sequential infiltration synthesis and pattern transfer using 6 nm half-pitch carbohydrate-based fingerprint block copolymer

This study presents how sequential infiltration synthesis of trimethyl aluminium and water into a carbohydrate-based block copolymer was used to enable pattern transfer of 6 nm half-pitch horizontal cylinders into silicon. Specular neutron reflectometry measurements of poly(styrene)-block-maltoheptaose self-assembled into horizontal cylinders indicate an increasing content of alumina after each se

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Formalized triage has been implemented in all Danish emergency departments. The validation behind formalized triage has focused on investigating predictive validity, i.e. correspondence between triage category and different outcome measures. Reliability is primarily investigated in terms of inter-rater reliability on written patient cases, and several studies have methodological limitations questi

Transient numerical modeling and model predictive control of an industrial-scale steam methane reforming reactor

A steam methane reforming reactor is a key equipment in hydrogen production, and numerical analysis and process control can provide a critical insight into its reforming mechanisms and flexible operation in real engineering applications. The present paper firstly studies the transport phenomena in an industrial-scale steam methane reforming reactor by transient numerical simulations. Wall effect a

Numerical and experimental aspect of coherent lensless imaging

This thesis is devoted to the understanding, application, and extension of coherent lensless imaging methods for microscopy purposes. Particular attention is given to the Fourier transform holography and coherent diffractive imaging methods.These two methods share several properties such as the ability for singleshot imaging and their experimental geometries, but differ greatly in their reconstruc

Multi-wavelength phase retrieval for coherent diffractive imaging

Phase retrieval is a numerical procedure concerned with the recovery of a complex-valued signal from measurements of its amplitude. We describe a generalization of this method for multi-wavelength data acquired in a coherent diffractive imaging experiment. It exploits the wavelength-dependent scaling of the support domain to recover separate reconstructions for each wavelength, providing new possi

Time trends in pediatric hand fracture incidence in Malmö, Sweden, 1950–2016

Background: The hand is the second most fractured region in children. It is therefore important to update fracture epidemiology to be able to identify time trends for adequate health care planning. This study reports pediatric hand fracture incidence 2014–2016 and, using published data, also long-term time trends in 1950–2016. Patients and methods: The Swedish city of Malmö, with 328,494 inhabitan

Analyses of thermal performance and pressure drop in a plate heat exchanger filled with ferrofluids under a magnetic field

This paper experimentally investigates the effect of various magnetic fields on the performance of a plate heat exchanger filled with ferrofluids. Spherical nanoparticles Fe3O4 with an average diameter of 20 nm are dispersed into DI-water to synthesize the ferrofluid. Thermal performance and flow characteristics of the ferrofluid with 0.1% particle concentration are investigated based on various a

Effects of hole configuration on film cooling effectiveness and particle deposition on curved surfaces in gas turbines

In this paper, effects of four different hole configurations on film cooling performance and particle deposition are investigated numerically on a curved surface. The RNG k-ε turbulence model is used, and the discrete phase model is developed by user-defined functions. The particle deposition on the curved surface is analyzed by calculated results of capture and impact efficiencies. Results show t

One detector, all the light elements – Low-background NRA, RBS and ERDA for the quantification of elements from hydrogen to fluorine

Presented is a review of the accomplishments, of the light-element program, conducted at the Lund Ion-Beam Analysis Facility. A detailed account is given of the current experimental setup at the total Ion-Beam Analysis Chamber, which is equipped with two Double-Sided Silicon Strip Detectors for charge particle detection, a silicon drift detector for PIXE analysis, an electrostatic deflection syste

Emergency department crowding and mortality in 14 Swedish emergency departments, a cohort study leveraging the Swedish Emergency Registry (SVAR)

Objectives There is evidence that emergency department (ED) crowding is associated with increased mortality, however large multicenter studies of high quality are scarce. In a prior study, we introduced a proxy-measure for crowding that was associated with increased mortality. The national registry SVAR enables us to study the association in a more heterogenous group of EDs with more recent data.