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Phylogenetic and Drug-Resistance Analysis of HIV-1 Sequences From an Extensive Paediatric HIV-1 Outbreak in Larkana, Pakistan

Introduction: In April 2019, an HIV-1 outbreak among children occurred in Larkana, Pakistan, affecting more than a thousand children. It was assumed that the outbreak originated from a single source, namely a doctor at a private health facility. In this study, we performed subtype distribution, phylogenetic and drug-resistance analysis of HIV-1 sequences from 2019 outbreak in Larkana, Pakistan. Me

Processing speed is affected by early impairment in kidney function in the general elder population

Background: Chronic kidney disease, cardiovascular disease, and cognitive dysfunction are common in the elder population. There is evidence of a connection between these conditions, possibly by a shared vascular pathogenesis. Processing speed is commonly impaired in cerebrovascular disease. Methods: The data was obtained from the population based study “Good aging in Skåne” (GÅS), and included 905

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Experimental studies are carried out to investigate the heat transfer performance of six different arrangements of truncated ribs in internal cooling channel by fixing the Reynolds number. The convective heat transfer mechanisms of the considered cases are detailed and analyzed based on the fluid flow characteristics by using three dimensional numerical simulations. The results show that among six

Unraveling the World’s Longest Non-stop Migration : The Indian Ocean Crossing of the Globe Skimmer Dragonfly

Insect migration redistributes enormous quantities of biomass, nutrients and species globally. A subset of insect migrants perform extreme long-distance journeys, requiring specialized morphological, physiological and behavioral adaptations. The migratory globe skimmer dragonfly (Pantala flavescens) is hypothesized to migrate from India across the Indian Ocean to East Africa in the autumn, with a

Effects of pin fins and vortex generators on thermal performance in a microchannel with Al2O3 nanofluids

This paper performs a comparative analysis to obtain the optimal cross-section shape and parameters of both pin fins and vortex generators. A novel combined structure with pin fins and vortex generators is proposed to enhance thermal performance of an integrated microchannel heat sink. Effects of nanoparticle diameter and volume fraction are investigated using Al2O3 nanofluid and DI-water as worki

Downturn in Childhood Bone Mass : A Cross-Sectional Study Over Four Decades

Screen time and physical inactivity have increased among children. As physical activity is a determinant of bone mass, there is a concern that children today have lower bone mass than earlier. If this is true, fractures may become more common in the future. In 2017–2018, we used single-photon absorptiometry (SPA) to measure distal forearm bone mineral density (BMD; mg/cm2) in a normative cohort of

Effect of an impinging jet on the flow characteristics and thermal performance of mainstream in battery cooling of hybrid electric vehicles

The novel concept of impinging jet cooling, i.e., an active-passive air cooling strategy, was proposed to achieve improved battery thermal management in hybrid vehicles, and this method is supported by excess high pressure discharged air. To comprehensively realize the active-passive combined cooling behavior, a rectangular channel with a jet impingement hole was utilized to experimentally and num

Application of artificial neural network to forecast engine performance and emissions of a spark ignition engine

Increasing the application of machine learning algorithms in engine development has the potential to reduce the number of experimental runs and the computation cost of computational fluid dynamics simulations. The objective of this study is to assess if such a statistical modelling approach can predict engine efficiency and emissions at any given condition for an already calibrated spark ignition

Improvement of cooling performance of hybrid nanofluids in a heated pipe applying annular magnets

In this paper, convective heat transfer of Fe3O4–carbon nanotubes (CNTs) hybrid nanofluid was studied in a horizontal small circular tube under influence of annular magnets. The pipe has an inner diameter of 3 mm and a length of 1.2 m. Heat transfer characteristics of the Fe3O4–water nanofluid were examined for many parameters, such as nanoparticle volume fraction in the range of 0.4–1.2% and Reyn

Coriolis and buoyancy effects on heat transfer in viewpoint of field synergy principle and secondary flow intensity for maximization of internal cooling

The present investigation emphases on rotation effects on internal cooling of gas turbine blades both numerically and experimentally. The primary motivation behind this work is to investigate the possibility of heat transfer enhancement by dean vortices generated by Coriolis force and U-bend with developing turbulent in the view point of the field synergy principle and secondary flow intensity ana

Observations of the effect of strong Pauli paramagnetism on the vortex lattice in superconducting CeCu2Si2

We present the results of a study of the vortex lattice in the heavy fermion superconductor CeCu2Si2, using small-angle neutron scattering (SANS). In this material at temperatures well below Tc∼0.6 K, the value of the upper critical field Bc2∼2.2 T is strongly limited by the Pauli paramagnetism of the heavy fermions. In this temperature region, our SANS data show an increase in the magnetization o

Heat transfer behaviors of some supercritical fluids : A review

Supercritical fluids (e.g., hydrocarbon fuels, water, carbon dioxide, and organic working medium, etc) have been recognized as working media to improve thermal efficiencies in power cycles and energy conversion, and have been used or selected as the working fluids in engineering fields such as aerospace, nuclear power, solar energy, refrigeration, geothermal energy, chemical technology, and so on.

Changes in bone mass associated with obesity and weight loss in humans : Applicability of animal models

The implications of obesity and weight loss for human bone health are not well understood. Although the bone changes associated with weight loss are similar in humans and rodents, that is not the case for obesity. In humans, obesity is generally associated with increased bone mass, an outcome which is exacerbated by advanced age and menopause. In rodents, by contrast, bone mass decreases in propor

Influences of accelerating states on supercritical n-decane heat transfer in a horizontal tube applied for scramjet engine cooling

Supercritical n-decane is applied in the regenerative cooling system of scramjet engines while scramjets are always in various irregular movements. With the desire to explore heat transfer performance of supercritical n-decane under actual flight conditions, numerical simulations and analysis of different states during the accelerated flight process are carried out under three different heat fluxe

Preparation and thermophysical property analysis of nanocomposite phase change materials for energy storage

Paraffin wax and various nanoparticles (CuO, Al2O3 and Fe3O4) were used as matrix and heat conduction enhancer of phase change materials (PCMs), respectively. The dispersant Span 80 was added into the nanocomposite to provide stable PCMs. Based on analyses of melting and freezing curves and infrared thermal imaging tests, the phase change latent heat, viscosity, and thermal conductivity of the nan

Metastable precursor structures in hydrogen-infused super duplex stainless steel microstructure – An operando diffraction experiment

We report the evolution of metastable precursor structures during hydrogen infusion in the near-surface region of a super duplex stainless steel. Grazing-incidence x-ray diffraction was employed to monitor, operando, the lattice degradation of the austenite and ferrite phases. Electrochemical hydrogen charging resulted in the splitting of the diffraction peaks of the austenite phase, suggesting th

Investigation of gas–liquid dispersion and mass transfer performance of wide-viscosity-range impellers in water solutions of xanthan gum

Wide-viscosity-range impellers have extensive demands and applications in process industry. The gas–liquid dispersion and mass transfer characteristics of wide-viscosity-range impellers including Large-double-blade (LDB) impeller, Fullzone (FZ) impeller and Maxblend (MB) impeller in water solutions of xanthan gum were investigated experimentally and compared. The influences of gas flow rate, impel

Flow Characteristics and Heat Transfer of Supercritical n-decane in Novel Nested Channels for Scramjet Regenerative Cooling

A novel kind of regenerative cooling channel, a so-called nested channel, is proposed to further reduce the combustion chamber wall temperature of a scramjet. The supercritical n-decane heat transfer in the horizontal up-channel and horizontal down-channel with different flow directions are numerically investigated. The temperature distribution, flow field, and vortex structure are presented to di

In situ studies of the cathodic stability of single-crystalline IrO2(110) ultrathin films supported on RuO2(110)/Ru(0001) in an acidic environment

We investigate with in situ surface X-ray diffraction (SXRD) and X-ray reflectivity (XRR) experiments the cathodic stability of an ultrathin single-crystalline IrO2(110) film with a regular array of mesoscopic rooflike structures that is supported on a RuO2(110)/Ru(0001) template. It turns out that the planarity of the single-crystalline IrO2(110) film is lost in that IrO2(110) oxide domains delam

High-Resolution X-ray Photoelectron Spectroscopy of an IrO2(110) Film on Ir(100)

High-resolution X-ray photoelectron spectroscopy (XPS) and density functional theory (DFT) were used to characterize IrO2(110) films on Ir(100) with stoichiometric as well as OH-rich terminations. Core-level Ir 4f and O 1s peaks were identified for the undercoordinated Ir and O atoms and bridging and on-top OH groups at the IrO2(110) surfaces. Peak assignments were validated by comparison of the c