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Putting the 'theory' back into grounded theory : Guidelines for grounded theory studies in information systems

Over the past decade, there has been increasing interest in the use of grounded theory in information systems research. Grounded theory is a qualitative research method that seeks to develop theory that is grounded in data systematically gathered and analysed. The purpose of this paper is to suggest guidelines for grounded theory studies in information systems. Our guidelines are based on a framew

AI-Driven Drug Response Prediction for Personalized Cancer Medicine

Artificial intelligence (AI) has been used to develop drug sensitivity prediction models, raising the opportunity of using it for personalized cancer medicine. This chapter describes recent advancements in drug response prediction methods using machine learning algorithms. Pharmacogenomic datasets come with different types of biological data including genetic mutations, gene expression, copy numbe

Att göra livet (över)levbart : Transpersoners ontiska, relationella och reflekterande arbete för att skapa minoritetsro och hantera utsatthet i vardagen

Transgender people report significantly poorer mental health than cisgender people. In psychological research, these health disparities are explained by theories of minority stress and microaggressions, while other disciplines use theories on normativity, livability, affective work, world making and utopias. Such theories are seldom picked up by psychologists even though they could serve to help p

PSA quantification of 80 plasma samples from the clinical routine using antibody microarrays

Antibody microarrays are becoming increasingly established in clinical studies. However, the arrays are seldom used in a quantitative approach but rather for detecting up or down regulated proteins. In this study we describe a microarray procedure being standardized by placing the in-house developed porous silicon surfaces into a commercially available 96 well microtiter plate for analyzing the PS

När ”spanskan” härjade vid akademin

Översiktlig artikel om hur spanska sjukan 1918 drabbade Lunds universitet och särskilt dess studenter samt om hur vissa professorer i medicin förhöll sig till den nya smittan.

Direct costs of glaucoma management following initiation of medical therapy. A simulation model based on an observational study of glaucoma treatment in Germany

Background: Economic evaluation of new treatments in the field of glaucoma represents a challenge. In the absence of a clear epidemiological link between intra-ocular pressure (IOP) and disease progression to blindness, the economic impact of treatments that lower IOP on long-term outcome cannot be estimated. As an alternative, effectiveness may be expressed as the ability to control IOP over time

A novel care guide for personalised palliative care – a national initiative for improved quality of care

BackgroundEven when palliative care is an integrated part of the healthcare system, the quality is still substandard for many patients and often initiated too late. There is a lack of structured guidelines for identifying and caring for patients; in particular for those with early palliative care needs. A care guide can act as a compass for best practice and support the care of patients throughout

GARD : Genomic allergen rapid detection

Genomic allergen rapid detection (GARD) is an in vitro assay for the prediction of skin sensitizing capacity of chemicals. The GARD assay monitors changes in the expression of 196 genes, termed the GARD prediction signature. In short, MUTZ-3 cells, representing a well-characterized in vitro model of human dendritic cells (DCs), are exposed to the test substances for 24 h. After RNA extraction and

‘Successful’ low-carbon energy transitions at the community level? An energy justice perspective

The aim of this paper is to critically analyse so-called ‘successful’ low-carbon energy transitions under the energy justice magnifying glass. We focus on two case studies that have been arguably referred to as successful local energy transitions in the literature: Samsø (Denmark) and Feldheim (Germany). The study examines community perspectives and causal inferences about perceived energy (in)jus

Transcultural novels and translating cultures : François Cheng's Le Dit de Tianyi and L'éternité n'est pas de trop

This article examines the two French-language novels by the Franco-Chinese migrant writer François Cheng, Le Dit de Tianyi (1998) and L'éternité n'est pas de trop (2002), and proposes to conceptualize them as two novelistic models of cultural translation. Cheng's engagement with, and departure from, canonical Western novelistic models such as Proust's A la recherche du temps perdu in Le Dit reveal

The music classroom in focus : everyday culture, identity, governance and knowledge formation

This article is based on a larger research project with the purpose to study how market aesthetics and student’s music culture are expressed in the Swedish music classroom. The empirical material consists of video observations of classroom activities in secondary school settings in Sweden. The theoretical framework consists of poststructuralist and social constructionist theory combined with theor

Science - policy interfaces in impact assessment procedures

Modelling tools used in impact assessment procedures can be regarded as tools for communication between science and policy. In order to create an integrated system for modelling not only the scientific components have to be in place but also the science/policy interfaces in the assessment procedures have to be identified and their social dynamics understood.To make a system like SEAMLESS Integrate