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Background: The Patient-Reported Indices for Multiple Sclerosis (PRIMUS) comprises a suite of three scales for assessing symptoms, activity limitations, and quality of life in multiple sclerosis (MS). It was developed in the UK and has been shown to have excellent psychometric properties. This study describes the adaptation of eight language versions for Canadian English, Canadian French, French,

We report on an x-ray scattering experiment of bulk poly[9,9-bis(2-ethylhexyl)fluorene] under quasihydrostatic pressure from 1 to 11 GPa at room temperature. The scattering pattern of high molecular weight (HMW) polyfluorene (>10 kg/mol) undergoes significant changes between 2 and 4 GPa in the bulk phase. The 110 reflection of the hexagonal unit cell disappears, indicating a change in equatorial i

Background: Steroid injections are used in idiopathic carpal tunnel syndrome (CTS), but evidence of efficacy beyond 1 month is lacking. Objective: To assess the efficacy of local methylprednisolone injections in CTS. Design: Randomized, placebo-controlled trial. (ClinicalTrials.gov: NCT00806871) Setting: Regional referral orthopedic department in Sweden. Patients: Patients aged 18 to 70 years with

The objective of the present study was to assess the safety and effectiveness of vernakalant hydrochloride injection (RSD1235), a novel antiarrhythmic drug, for the conversion of atrial fibrillation (AF) or atrial flutter to sinus rhythm (SR) Patients with either AF or atrial flutter were randomized in a 11 ratio to receive vernakalant (n = 138) or placebo (n = 138) and were stratified by an arrhy

The phenomenon of adopting open source software development practices in a corporate environment is known by many names, one being inner source. The objective of this study is to investigate how an organization consisting of small development teams can benet from adopting inner source and assess the level of applicability. The research has been conducted as a case study at a software development c

In the study of motor systems it is often necessary to track the movements of an experimental animal in great detail to allow for interpretation of recorded brain signals corresponding to different control signals. This task becomes increasingly difficult when analyzing complex compound movements in freely moving animals. One example of a complex motor behavior that can be studied in rodents is th

1. State space models are starting to replace more simple time series models in analyses of temporal dynamics of populations that are not perfectly censused. By simultaneously modelling both the dynamics and the observations, consistent estimates of population dynamical parameters may be obtained. For many data sets, the distribution of observation errors is unknown and error models typically chos

A non-Gaussian time series with a generalized Laplace marginal distribution is used to model road topography. The model encompasses variability exhibited by a Gaussian AR(1) process with randomly varying variance that follows a particular autoregressive model that features the gamma distribution as its marginal. A simple estimation method to fit the correlation coefficient of each of two autoregre

We propose a simple, general and computationally efficient algorithm for maximum likelihood estima- tion (MLE) of parameters in diffusion and jump-diffusion processes. This is conducted within a Monte Carlo EM-algorithm, where the smoothing distribution is computed using resampling. The results are encouraging as we can approximate the MLE well for the models studied when using simulated data. We

We present an approach to process scheduling based on an abstract graph representation which captures both data-flow and the flow of control. Target architectures consist of several processors, ASICs and shared busses. We have developed a heuristic which generates a schedule table so that the worst case delay is minimized. Several experiments demonstrate the efficiency of the approach.

A general approach to derive summation rules in electromagnetics using Herglotz functions is presented in this paper. This approach is then used to obtain summation rules and bounds on partial wave scattering, which are illustrated numerically by the scattering of a Drude sphere.

The Somalia Reconciliation Conference led by the Intergovernmental Authority on Development (IGAD), in Eastern Africa, is focusing on creating a basis for dialogue as a means of reaching peace and stability in the region (Somali Reconciliation Conference, 2003; IGAD, 2002). This paper deals with the critical implications with focusing on dialogue as a means of promoting long-term peace.