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Despite impressive advances in theories, methods and technologies, crystallization still remains a serious bottleneck in structural determination of macromolecules. Here we present a novel solid-liquid interface method (SLIM) for protein crystallization, based on the pre-adding and drying of a crystallization reagent, and thereafter the dispensing of a protein solution to the dried media to initia

As part of a structural genomics platform in a university laboratory, a low-cost in-house-developed automated imaging system for SBS microplate experiments has been designed and constructed. The imaging system can scan a microplate in 2-6 min for a 96-well plate depending on the plate layout and scanning options. A web-based crystallization database system has been developed, enabling users to fol

To facilitate the justification of an X-ray or nuclear medicine investigation and for informing patients, it is desirable that the individual patient's radiation dose and potential cancer risk can be prospectively assessed and documented. The current dose-reporting is based on effective dose, which ignores body size and does not reflect the strong dependence of risk on the age at exposure. Risk es

Public clouds such as Amazon Web Services (AWS) and Microsoft’s Azure provide excellent capabilities for scalable Web applications and Hadoop-based processing. Recent ad- ditions to public clouds to support connected devices and IoT have the potential to similarly disrupt emerging home- grown and/or proprietary approaches. While early public cloud IoT success stories have focused on smaller-scale

The collection of chapters in this book present the concept of matched filters: Response characteristics “matching” the characteristics of crucially important sensory inputs, which allows detection of vital sensory stimuli while sensory inputs not necessary for the survival of the animal tend to be filtered out, or sacrificed. The individual contributions discuss that the evolution of sensing syst

We argue that social robots should be designed to behave similarly to humans, and furthermore that social norms constitute the core of human interaction. Whether robots can be designed to behave in human-like ways turns on whether they can be designed to organize and coordinate their behavior with others’ social expectations. We suggest that social norms regulate interaction in real time, whereage

Multifunctional agriculture provides noncommodity functions and services along with food, feed and bioenergy feedstocks, for example by preserving or promoting biodiversity, improving soil fertility, mitigating climate change and environmental degradation, and contributing to the socio-economic viability of rural areas. Producing biomass for bioenergy from low-input perennial species mixtures on m

We are developing a new technique to apply transition-edge sensors (TESs) to X-ray spectroscopy of exotic atoms, especially of kaonic atoms. To demonstrate the feasibility of this pioneering project, performance of a TES-based X-ray detector was evaluated in pion- and kaon-beam environments at particle accelerators.We successfully observed X-rays from pionic-carbon atoms with a resolution as good

This chapter is centered on the importance of letting learners take the lead in their lifelong educational journey, meeting the challenges that they encounter. Additionally, the chapter focuses on new modes of learning in the digital era. The role transfers and professional development of managers, leaders, and academics are discussed, as well as the need for the development of digital academic sc

Objective: To determine if blood neurofilament light chain (NfL) protein can discriminate between Parkinson disease (PD) and atypical parkinsonian disorders (APD) with equally high diagnostic accuracy as CSF NfL, and can therefore improve the diagnostic workup of parkinsonian disorders. Methods: The study included 3 independent prospective cohorts: the Lund (n = 278) and London (n = 117) cohorts,

In 1992 the Core Assessment Program for Intracerebral Transplantations (CAPIT) was published providing the minimal requirements for a common patient evaluation protocol. Despite the intent, the program was thought to be too laborious to carry out in large scale trials, and it also lacked evaluations of cognitive functions and quality of life. Moreover, the CAPIT was designed for neural transplanta

Nanowire array solar cells show intrinsic light trapping and absorption enhancement properties due to the diffraction and optical resonances. Here, we report the effect of varying incidence angle on the performance of GaAs nanowire array solar cells. We provide experimental evidence that nanowire array solar cells are highly efficient at gathering diffuse or tilted incident light, even at very hig

Many subjects have a negative spike in the beginning of a saccade in electro-oculographic signals. The amplitude of the spike depends on the location of the electrodes. The spike distorts the saccades and causes errors in the parameters. The saccade spike can assist in the identification of small saccades. A syntactic technique based on formal languages and parsing is presented which looks for spi

Several recent studies of solar twins in the solar neighbourhood have shown a tight correlation between various elemental abundances and age, in particular [Y/Mg]. If this relation is real and valid for other types of stars as well as elsewhere in the Galaxy, it would provide a very powerful tool to derive ages of stars without the need to resort to determining their masses (evolutionary stage) ve