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Development Studies – a personal reflection on the beginning
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Production of Perdeuterated Proteins in Escherichia coli for Structural Studies by Neutron Crystallography
Neutron macromolecular crystallography (NMX) is a complementary technique to X-ray crystallography leveraging neutron scattering properties of the hydrogen isotope deuterium (2H). Production of deuterium labelled molecules together with large crystal requirements for neutron crystallography are few of several bottlenecks limiting implementation of this technique for a wider range of proteins. Perd