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Popular Abstract in Swedish Transplantation av nervvävnad till hjärnan är inte en ny idé. Redan 1890, publiserade Thompson de första försöken att transplantera vuxen hjärnvävnad till det vuxna centrala nervsystemet och han rapporterade att vävnaden överlevde i sju veckor "without wholly losing its identity". Trots detta var det först under 1970-talet som metoderna för intracerebral nervcellstranspIntracerebral neuronal transplantation have been shown to ameliorate symptoms of brain dysfunction in both animals models and Parkinson's disease, although problems still remain. The newly introduced technique of ex vivo gene transfer could serve as an alternative approach, possible avoiding some of the draw-backs of the embryonal tissue used in neuronal grafting. We have investigated the feasibli

Using simple waves and six-vector formalism, the propagation of electromagnetic waves in nonlinear, bianisotropic, nondispersive, homogeneous media is analyzed. The Maxwell equations are formulated as an eigenvalue problem, whose solutions are equivalent to the characteristic directions of the wave front. Oblique incidence of plane waves in vacuum on a half space of nonlinear material is solved, g

Methane is a powerful greenhouse gas and growing concern regarding global climate changes over the last years has pointed out the need to quantify and control the leaking of methane into the atmosphere. Landfill gas is regarded as one of the major sources for methane migration to the atmosphere. In this study we present research work with the objective to evaluate the use of geoelectrical resistiv

Planar droplet sizing (PDS) is a technique relying on the assumption that laser-induced fluorescence (LIF) and Mie scattering optical signals from spherical droplets depend on their volume and surface area, respectively. In this article, we verify the validity of this assumption by experimentally analyzing the light intensity of the LIF and Mie optical signals from micrometric droplets as a functi

The holotype (KUVP 1301) of Styxosaurus snowii—one of the earliest described elasmosaurid plesiosaurians—consists of a well-preserved cranium, mandible and articulated sequence of anterior–mid-series cervical vertebrae found in the lowermost Campanian strata of the Smoky Hill Chalk Member in the Niobrara Formation of Kansas, USA. This particular specimen has proven important for recent phylogenies

During the recent years improved operation techniques and administrative procedures have been developed for early rehabilitation. At the same time preoperative lifestyle intervention (prehabilitation) has revealed a large potential for additional risk reduction. The aim was to assess the quality of life and to estimate the cost-effectiveness of standard care versus an integrated programme includin

Background: Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT) is a promising yet not curative approach in castration-resistant (CR) prostate cancer (PC). Rational combination therapies may improve treatment efficacy. Here, we explored the effect of androgen receptor blockade (ARB) on PSMA expression visualized by PET and its potential additive effect when combined with 1

An approach for large scale protein identification and quantification was described. The peptide mixtures from the strong cation exchange (SCX) fractionated protein digests were separated and analyzed by HPLC MS/MS. The human fibrobalst nuclei were purified from stimulated and non-stimulated cells. The quantification results with MALDI and ESI LC/MS were shown to be identical within experimental e

Most pastoralists’ in Sub Saharan Africa (SSA) are adversely affected by climate-change related shocks such as droughts and livestock diseases. These shocks lead to deterioration of livestock quality and even mass death of herds. This leaves pastoralists vulnerable as they derive most of their food and income needs from livestock, necessitating emergency disaster response and the need to build the

Large cohorts of carefully collected clinical tissue materials play a central role in acquiring sufficient depth and statistical power to discover disease-related mechanisms and biomarkers of clinical significance. Manual preparation of such large sample cohorts requires experienced laboratory personnel. This carries other possible downsides such as low throughput, high risk of errors, and low rep