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Human pluripotent stem cell-derived in vitro models, combined with advances in high-content live-cell calcium imaging, provide a powerful platform for disease modeling and drug screening. However, most calcium imaging analysis tools have been developed for in vivo applications with suboptimal features for processing data from cultured neurons. Here, we present LUMIN (Live-cell User Module for Imag
One of the key ecological processes affected by climate change is plant carbon uptake. However, there is substantial uncertainty about how plant carbon uptake will respond to warming in mountain ecosystems, which are known for sharp temperature gradients and abrupt shifts in vegetation structure. Specifically, we lack an understanding of whether these response trajectories over time will be linear
Al-Ga-based alloys are promising carriers of renewable energy, which can provide hydrogen by hydrolysis in challenging working environments. Manipulating their performance by different process conditions and comprehending the mechanisms are important for achieving directional design synthesis of alloys and enhancing their practicality. This study presents a novel approach to optimizing the hydroge
A quantitative understanding of the hydro-environmental factors that influence the occurrence of agricultural drought events would enable more strategic climate change adaptation and drought management plans. Practical drought hazard mapping remains challenging due to possible exclusion of the most pertinent drought drivers, and to the use of inadequate predictive models that cannot describe droug
Considering the ever increasing financial damages of floods and the need to manage the surface water, the use of new and more sufficient methods seems to be necessary. Therefore, the present study aims to investigate capability of the Gamma, Beta, Chi-square, and Weibull probability distribution functions (PDFs) for flood hydrograph derivation. The present study was conducted in the Bar watershed,
PurposeThis study aims to investigate how stakeholder cocreation in 3D city mapping initiatives can extend the role of digital urban platforms beyond administrative efficiency toward the negotiation and enhancement of place attractiveness. Drawing on a participatory case study of Trollhättan, Sweden, the paper explores the needs, expectations and aspirations articulated by diverse stakeholder grou
Evaluating the repellency of essential oils against Tetranychus urticae requires robust methodologies to detect time-dependent changes in their efficacy, due to differential efficacy, volatility, and sustained effectiveness. This study introduces the Pole-dance bioassay, a novel no-choice method optimized for high-throughput screening of time-dependent repellency, demonstrated through tests on twe
Recognizing the challenges in using botanicals as sustainable pest control agents due to compositional variation, this study addresses the limitations of traditional component-based approaches such as Hewlett and Plackett or Wadley’s models. Based on the assumption of noninteractivity among constituents, these models often fail to predict outcomes accurately due to dynamic intermolecular interacti
Along with the gradually accelerated urbanization process, simulating and predicting the future pattern of the city is of great importance to the prediction and prevention of some environmental, economic and urban issues. Previous studies have generally integrated traditional machine learning with cellular automaton (CA) models to simulate urban development. Nevertheless, difficulties still exist
En betydande del av Sveriges nationella ungdomspolitik syftar till att ge ungdomar större inflytande över samhällsutvecklingen. De målformuleringar som staten skapat genom bland annat regeringens liggande ungdomspolitiska proposition, har intresserat oss. Denna uppsats behandlar de normer som staten, genom olika dokument och skrifter, konstruerar för hur ungdomars politiska engagemang bör organise
Konflikten i Tjetjenien har blivit ett ihärdigt problem för såväl ryssar som tjetjener. Konflikten kan delas in i två faser, det första och det andra kriget. Våra studier av det empiriska materialet ledde till en misstanke om att det fanns luckor i den befintliga forskningen, i synnerhet gällande det andra kriget. Resultatet blev en teoriutvecklande studie om det andra Tjetjenienkrigets uppkomst o
The purpose of this essay was to further develop the discussion around the street-level bureaucrats and the dilemmas that they meet in their work environment. The paper will try to accomplish this by putting the spotlight on the professional role, the organizational control of the street-level bureaucrat and the effect of society on the work environment. Something that also will be discussed is th
William G. Lycan undersöker i sin bok Philosophy of Language: a Contemporary Introduction möjligheten att förklara lingvistisk mening utifrån verifikationismen. Han lägger fram en mängd invändningar som tillsammans skall omkullkasta projektet. Då jag läst Lycans argument några gånger slås jag av det attraktiva med verifikationismens idé och av att jag vill syna kritiken lite närmre. Sammanfattning
Vi har i vårt uppsatsarbete valt att studera de fackligt engagerade arbetsplatsombudens vardag ur ett pedagogiskt perspektiv. Då vår frågeställning är av explorativ art ansåg vi att en kvalitativ ansats var att föredra. Vi har genomfört ett antal semistrukturerade intervjuer med dels utbildningsansvariga vid två regionalavdelningar samt ett antal arbetsplatsombud. Vid genomförandet av intervjuerna
There are reasons to believe that recent changes in the Swedish academic library environment create new images of identity. New information technology, changed educational methods and increasing numbers of students in higher education heavily influence the professional basis for librarians. The purpose of this essay is to examine and describe how the images of identity are conceived and expressed
Deliberative politics offers a new and exiting way of overcoming the problems that the western democracy of today is facing. A lot of research in the most recent years have had the goal to replace the representative democracy with a decision-making frame built on decentralization and deliberation. The goal for this essay is to create a framework for local decision-making, based on deliberativ norm
In this essay I discuss different normative foundations - theories of political ethics, for proposed cures to market failures. In addition to empirically match what cure fit what type of market failure, I posit the notion that the normative position of an economist, or policy maker, or of a group, concerned with these problems, delimits the options available for recommending, or analysing, what co
Under våren 2006 antog den dåvarande riksdagen en ny lag (2006:440) om ändring i lagen (1982:80) om anställningsskydd. Den nya lagen innehåller bland annat regler som ska sträva mot att regelverket förenklas och att skyddet för tidsbegränsat anställda förstärks. De nya reglerna innebär bland annat ett färre antal former för tidsbbegränsade anställningar. Möjligheten att under en längre tid stapla
Eftersom anskaffningskostnaderna för flygplan är så höga idag, finns det behov inom luftfarten av andra finansieringsformer än direkta köp. Exempel på sådana alternativa former är villkorade förvärv, leasing och inteckningar i luftfartyg. Dessa transaktioner är beroende av att borgenärerna ges en stabil säkerhet. Uppsatsens syfte är att undersöka det sakrättsliga skyddet av rättigheter i luftfarty
