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Genome wide association studies (GWAS) identify susceptibility loci for complex traits, but do not identify particular genes of interest. Integration of functional and network information may help in overcoming this limitation and identifying new susceptibility loci. Using GWAS and comorbidity data, we present a network-based approach to predict candidate genes for lipid and lipoprotein traits. We

Background: The aim was to investigate whether the effects of major risk factors for ischemic stroke were modified by long-term exposure to air pollution in Scania, southern Sweden. Methods: Cases were defined as first-ever ischemic strokes in patients born between 1923 and 1965 during 2001-2006 (n = 7,244). Data were collected from The Swedish National Stroke Register (Riks-stroke) and the Malmo

Objective The Systemic Lupus International Collaborating Clinics (SLICC) group revised and validated the American College of Rheumatology (ACR) systemic lupus erythematosus (SLE) classification criteria in order to improve clinical relevance, meet stringent methodology requirements, and incorporate new knowledge regarding the immunology of SLE. Methods The classification criteria were derived from

The aim of this qualitative study was to investigate the social identity of students at upper secondary school for physically disabled students. The youths I drew my attention to suffered from severe physical disabilities and therefore received specially adapted education in small classes, but integrated at an ordinary upper secondary school. By "social identity" I mean how the students

This master’s thesis aims to investigate how pilotage contributes to maritime safety and if its criteria can be more risk-based in Sweden. The theory of Resilience Engineering was applied to maritime safety which has extended the concept further. Several aspects of how pilots contribute to maritime safety were identified within the literature and empirical studies. These aspects were the pilots

Med utgångspunkt i en rättsdogmatisk metod har denna framställning syftat till att utreda gällande rättsläge beträffande otjänliga försök inom dansk och svensk straffrätt. Mer specifikt är det straffansvarets omfattning vid otjänliga försök som undersökts genom en kritisk komparation mellan svensk och dansk rätt. Som en konsekvens av en vag lagtext i 23 kap. 1 § BrB är otjänliga försök inom svenBy a legal dogmatic method, this thesis has intended to investigate the legislation in force regarding harmless attempted crimes within Danish and Swedish criminal law. More specifically, the scope of criminal liability in the case of harmless attempts has been examined through a critical comparison between Swedish and Danish law. Harmless attempted crimes are because of an indistinct text of la

Background: The quantification of the relationships between walking and health requires that walking is measured accurately. We correlated different measures of step accumulation to body size, overall physical activity level, and glucose regulation. Methods: Participants were 25 men and 25 women American Indians without diabetes (Age: 20-34 years) in Phoenix, Arizona, USA. We assessed steps/day du

The purpose of this study is to examine how social service handles incorrect information about them that is spreading on social media. This study is based on a qualitative method. In order to achieve the purpose of this work, the focus has been on the unit of child protection services and seven social workers have been interviewed. The study shows that social workers only handle incorrect informat

Medierna spelar en viktig roll i hur vi formar våra värderingar och uppfattningar om omvärlden. Mediernas sätt att framställa ett fenomen är i hög grad avgörande för vårt sätt att förstå det. Främlingsfientlighet och rasism är ämnen som har fått stor betydelse på senare tid då extremhögern har varit på frammarsch runt om i Europa. Det är därför viktigt att studera vilken roll medierna har i detta

Emissions of greenhouse gases through human activities, predominantly in sectors such as energy production, land use, lifestyle, and production, are continuing to warm the planet to unsustainable degrees. An important way to regain control of the situation is a worldwide adjustment in the way we produce energy, from fossil fuels to sustainable and renewable energy sources. An example of such a ren

Denna kandidatuppsats fokuserar på påverkan som E-lärande och lösenordsstyrkemätare (LSM) har för att förbättra lösenordsstyrkan bland universitetsstudenter. Syftet med studien är att utforska hur dessa verktyg separat och i kombination påverkar användares lösenordsstyrka. Studien använder en kvasi-experimentell metod för att analysera hur dessa olika interventioner, i form av E-lärande och LSM, p

This study has been conducted to show the meaning of how background factors and attitudes affect the usage of chemical products in urban gardens in Lund. This was performed with the use of a questionnaire that was sent out to two Facebook groups, Lunds Trädgårdssällskap and another private group oriented towards people who live in or come from Lund. From an environmental perspective, this study is

Syfte: Att utveckla och validera ett kliniskt användbart frågeformulär för utvärdering av effekten av en kurs i Aktiv Kommunikation (AK). Metod: Ett frågeformulär utvecklades och reviderades utifrån kommentarer sprungna ur granskning genomförd av en grupp tidigare kursdeltagare och av ett antal kursledare i Aktiv Kommunikation. Formuläret fylldes sedan i av 61 andra, tidigare kursdeltagare. Ytterl

This essay presents a study regarding the processing of the personal data of a driver in an automated and connected vehicle in regards to the General Data Protection Regulation (“GDPR”). The investigation focuses on the lawfulness of processing and particularly on the legal bases consent, performance of a contract, legitimate interest and legal obligation. The aim of this study is to analyse under

Background: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients with severe asthma eligible for both anti-IgE and anti-IL5/5R and to compare the effectiveness of both classes of treatment in real life. Methods: This was a prospective cohort s

The widespread decline of insect pollinators poses a conservation concern and threatens both the pollination of wild plants and crops. Primary drivers of pollinator decline are habitat loss, degradation and fragmentation, which to a large extent result from agricultural intensification. Numerous tools have been developed to aid decision-making relating to insect pollinators and pollination in agri

Introduction Firefighters have increased risk of chronic respiratory disease. Standard clinical techniques used in medical checkups may not detect the earliest microstructural changes in peripheral airways. A new technique called Airspace Dimension Assessment (AiDA) has been shown to enable early detection of emphysema in COPD. This method may be useful in the occupational setting to detect early