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Background: Inducible nitric oxide synthase (iNOS) is a key driver of aberrant angiogenesis in inflammatory conditions and cancer, making it an attractive therapeutic target. Nevertheless, its function can be affected by the complex immune responses and tumor microenvironment (TME). Hence, combinatorial treatment approaches that simultaneously target iNOS and immune-modulatory signaling are strong
This study reports the synthesis and characterization of heterogeneous acid catalysts derived from rice husk biochar, modified by sulfonation and Ce(NO3)3·6H2O (cerium (III) nitrate hexahydrate) impregnation, for fatty acid esterification using methyl acetate as a glycerol-free reaction route. The research aims to valorize agricultural residues as renewable and sustainable precursors for solid aci
Gästkrönika. Den samlade forskningen är tydlig – det finns mycket som kan göras för att öka skogens klimatnytta. Det avgörande är att förstärka och värna kolsänkan samt att använda en större del av träråvaran till en ny mix av produkter. Det skriver Markku Rummukainen, professor på centrum för miljö- och klimatvetenskap vid Lunds universitet.
This paper examines income and employment outcomes for immigrants in Sweden’smost immigrant-dense neighbourhoods between 1998 and 2022. While relativeemployment among immigrants has improved, relative incomes in theseneighbourhoods have stagnated or declined. The most plausible explanation for thepersisting income gap and the shrinking employment gap between immigrant-dense and other neighbourhood
Byggnadssektorns klimatpåverkan behöver minskas genom energieffektivisering men också genom att öka andel av förnybar energi i den energi som används. Värmelagring i byggnader kan vara ett effektivt sätt att flytta byggnadens behov av energianvändning för uppvärmning från tider då energisystemets koldioxidbelastning är hög till tider under ett dygn då det finns betydande tillgång på förnybar energ
This article argues for a coalitional and comparative public theology as a new approach to the study of Global Christianity. This theology analyzes and assesses practices of living together in postmigrant societies. The article takes the shift from diverse migrant societies to superdiverse postmigrant societies that shapes many cities across Europe as a point of departure to scrutinize the role of
Assessment of the most appropriate groundwater conditioning factors (GCFs) is essential when performing analyses for groundwater potential mapping. For this reason, in this work, we look at three statistical factor analysis methods-Variance Inflation Factor (VIF), Chi-Square Factor Optimization, and Gini Importance-to measure the significance of GCFs. From a total of 15 frequently used GCFs, 11 mo
The alleged relation between mental disorder and violent criminal behaviour has been investigated mainly from an epidemiological perspective. Population-based registry studies have shown that violence occurs more frequently among people with mental disorders, like schizophrenia and bipolar disorder, compared with control subjects, but that the increased risk is largely mediated by drug abuse and s
Objective:To evaluate short- and long-term outcomes after modified Stage-I (mStage-I) palliation for hypoplastic left heart syndrome (HLHS).MethodsThis retrospective single-centre study analyzed 128 patients with HLHS treated between 1993 and 2023. Patients were divided into two groups: Era-I (n=36), from 1993 to 2001, who underwent the classic Norwood procedure, and Era-II (n=92), from 2002 to 20
Study regionThe study encompasses Sweden (450 000 km2) located on the Scandinavian Peninsula in northern Europe.Study focusWe quantified the future crop-water demand and water-irrigation needs of 30,000 km² arable land across Sweden to prepare for climate adaptation. We applied a spatially distributed catchment-scale (40,000 sub-basins) hydrological model with an irrigation routine according to FA
Deliverable D3.3 is the result of T3.3 Develop context-enriched operational guidelines for AI research areas.The aim of T3.3 was “to identify and lift overarching ethical concerns by cross-analysing use cases toimplement the bottom-up co-creation of context-enriched non-technical AI ethics guidelines” per AIresearch area (cf. AIOLIA DoA). The AI research areas covered in this deliverable are Gener
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease caused by the selective loss of upper and lower motor neurons. There is a considerable variability in the disease progression of sporadic ALS, but the molecular basis for phenotypic heterogeneity remains largely unknown. ALS patients often manifest systemic metabolic abnormalities such as glucose intolerance and hyperme
Although the Chinese government claims respect of human rights, it seems that the official Chinese conception of these rights is not only different from but also challenges the dominant international conception - this Chinese challenge of the international human rights regime constitutes the problem area of this thesis. Using a Laclau and Mouffe inspired discourse analysis strategy to deconstruct
Det råder stor osäkerhet angående bestämningen av den ersättning som bör utgå för det som kallas miljö- eller företagsskada. Miljö- och företagsskada har sin grund i olika lagstiftningar, 32 kap. MB respektive 2 § 4 kap. ExL, men avser i praktiken samma faktiska skada. Vid bestämning av den ersättning som bör utgå används samma modeller och praxis för att bedöma skadan. Den modell som idag har stöRoads can cause surrounding property units’ disturbances that negatively affect the property values. The disturbances are created by the activity on the road and typically include increased noise, impairment of the view, vibration, dust and light pollution. Under certain circumstances the property owner is entitled to compensation for the damages, which should be commensurate with the decrease in
The chirality-flow formalism has proven to simplify the calculations of helicity amplitudes to the extent that the matrix element corresponding to a Feynman diagram can immediately be written down. It has also shown to speed up the computation of scattering amplitudes through numerical implementations in MadGraph5_aMC@NLO. In this thesis we investigate if automated computation of amplitudes can be
Streets of Recovery explores how urban environments affect stress levels and how streets can be designed to support well-being. While existing research largely emphasises parks and green spaces, this study focuses on streets as everyday environments with the potential to influence stress. If urban environments shape stress levels, they also hold the potential to mitigate them. The thesis examines
