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Many of today’s health care facilities are outdated and no longer efficiently support processes. The various development trends in changing health care services seem to support more frequent use of modular facilities. Modular facilities and their development, however, face the challenge of combining a customized, user-centric design for special customer needs with the rapid delivery of prefabricat

The development of business ecosystems in smart cities is currently hampered by the absence of established approaches for facilitating long-term value and sustainability. In our view, the underlying reason is the lack of collective action involving various organizations in the design process. Collective action for the good of the whole ecosystem does not take place in existing participatory practi

We describe a NOVel form of Adaptive softening (NOVA) for collisionless N-body simulations, implemented in the RAMSES adaptive mesh refinement code. In RAMSES - that we refer to as a 'standard N-body method' - cells are only split if they containmore than eight particles (amass refinement criterion). Here, we introduce an additional criterion that the particle distribution within each cell be suff

INTRODUCTION: Beta-cell replacement by human islets or whole pancreas offers a life-saving therapeutic remedy for patients suffering from type 1 diabetes, providing considerable advantages with respect to diminishing total daily insulin dose and lowering frequencies of debilitating hypoglycemic reactions as well as preventing chronic micro- and macrovascular complications. Although remarkable prog

The aim with this paper is to examine how different GIS-based visualization methods can be applied and come to practical uses in the emergency service’s fire preventive work. These techniques motivate and facilitate various forms of fire prevention such as selection of areas or neighborhoods, blocks or buildings before home visits, identification and targeting of different risk groups and customiz

The aim is to illustrate how web marketing frame commercial baby food as a value-adding part of weaning practice and discuss how various ways of framing relate to contemporary mothering ideals. Drawing on “practice” and “frame analysis,” we illustrate how four baby food producers’ web marketing frame commercial baby food and weaning as “medical,” “fun” or “convenient.” The analysis shows that the

In order to improve curve safety, warning signs are used to alert drivers to unexpected changes in horizontal alignment and speed variations. While all countries have standards and guidelines for signs, markings and delineations to ensure a uniform system, they do not use them in the same way and choices and combinations may differ. SAFESTAR project promoted a method for establishing uniform curve

Car-sharing systems with electric vehicles are an alternative to reduce commuting times in big cities and also to mitigate air pollution. Car-sharing exists in 1100 cities around the world. These systems have had positive effects in the cities, replacing between 9 and 23 private vehicles for each car. This document proposes a public car-sharing system for Bogotá. The article focuses on the design

This review summarizes – with the practicing hematologist in mind – the methods used to determine measurable residual disease (MRD) in everyday practice with some future perspectives, and the current knowledge about the prognostic impact of MRD on outcome in acute myeloid leukemia (AML), excluding acute promyelocytic leukemia. Possible implications for choice of MRD method, timing of MRD monitorin

I ärendets beredning har deltagit universitetslektor Åsa Knaggård och postdoc RogerHildingsson vid Statsvetenskapliga institutionen samt universitetslektor BengtJohansson och professor Lars J. Nilsson vid Avdelningen för miljö- och energisystem,Lunds tekniska högskola. Vidare har professor Markku Rummukainen, professorHenrik Smith; professor Katarina Hedlund och utredare Mark Brady, samtligavid Ce

Throughout time, communities have adapted to changes in their environment and, in doing so, have addressed risksthat threaten the things they value. The need to adapt is considered more urgent now than ever, notably given thecurrent focus on climate risk. Typically, adaptation is presented as a solution to reduce such risks. This is particularlythe case for Landlocked Developing Countries and Smal

Botulinum neurotoxin B is a Food and Drug Administration-approved therapeutic toxin. However, it has lower binding affinity toward the human version of its major receptor, synaptotagmin II (h-Syt II), compared to mouse Syt II, because of a residue difference. Increasing the binding affinity to h-Syt II may improve botulinum neurotoxin B's therapeutic efficacy and reduce adverse effects. Here we ut

The predictions of chiral perturbation theory for the weak non-leptonic decays of hyperons are examined beyond the leading order. For the S-wave amplitudes we find that the leading corrections to lowest order chiral perturbation theory preserve the vanishing of the Σ+ → nπ+ amplitude. However, the Lee-Sugawara relation gets a large correction indicating a breakdown of chiral perturbation theory fo

We present a protocol for performing gas spectroscopy using infrared degenerated four-wave mixing (IR-DFWM), for the quantitative detection of gas species in the ppm-to-single-percent range. The main purpose of the method is the spatially resolved detection of low-concentration species, which have no transitions in the visible or near-IR spectral range that could be used for detection. IR-DFWM is