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Background: Evidence from prospective studies on intake of meat and fish and risk of squamous cell carcinoma (SCC) of the upper aero-digestive tract (UADT) is scarce. We prospectively investigated the association of meat and fish intake with risk of SCC of the UADT and the possible mechanism via heme iron in the large multicenter European Prospective Investigation into Cancer and Nutrition (EPIC)

Syria, as well as many other countries in the Middle East, faces serious water shortage problems. Available water per capita (AWPC) will dramatically decrease due to climate change, population increase, and water needed for economic growth. Rainwater harvesting can play an important role in increasing available water in Syria. However, the absence of rainwater sewer systems in many rural areas in

OBJECTIVE: The capability of the protein NEDD4L to reduce renal tubular expression of epithelial Na+ channel (ENaC) is influenced by a functional rs4149601 G→A NEDD4L polymorphism. As diuretics and β-blockers inhibit renal sodium reabsorption and renin release, respectively, we hypothesized that the β-blocker or diuretic-induced blood pressure reduction and prevention of cardiovascular disease wou

Objective. GFR-prediction equations based upon cystatin C and creatinine have better diagnostic performance in estimating GFR than equations based upon only one of the two markers. The present work concerns in what way a comparison between separate estimations of GFR based upon cystatin C (eGFR(cystatin C)) or creatinine (eGFR(creatinine)) can be used to evaluate the diagnostic performance of a co

OBJECTIVEYounger age at menarche, a marker of pubertal timing in girls, is associated with higher risk of later type 2 diabetes. We aimed to confirm this association and to examine whether it is explained by adiposity.RESEARCH DESIGN AND METHODSThe prospective European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct case-cohort study consists of 12,403 incident type 2 diabetes

Technical infrastructures of the society are becoming more and more interconnected and interdependent, i.e. the function of an infrastructure influences the function of other infrastructures. Disturbances in one infrastructure therefore often traverse to other dependent infrastructures and possibly even back to the infrastructure where the failure originated. It is becoming increasingly important

Society depends on services provided by critical infrastructures, and hence it is important that they are reliable and robust. Two main approaches for gaining knowledge required for designing and improving critical infrastructures are reliability analysis and vulnerability analysis. The former analyses the ability of the system to perform its intended function; the latter analyses its inability to

Background: Observational studies implicate higher dietary energy density (DED) as a potential risk factor for weight gain and obesity. It has been hypothesized that DED may also be associated with risk of type 2 diabetes (T2D), but limited evidence exists. Therefore, we investigated the association between DED and risk of T2D in a large prospective study with heterogeneity of dietary intake. Meth

Colorectal cancer (CRC) is the third most common cancer globally, with approximately 1.2 million new cases every year. The highest incidence rates are seen in developed countries, thereby imposing dietary and lifestyle factors in the etiology of CRC. Accumulating epidemiological evidence suggests that obesity is a risk factor for CRC in particular in men, as weak or no associations are seen in wom

I samband med framarbetandet av 36 § avtalslagen uttrycktes olika uppfattningar vad beträffar hur domstolarnas avgöranden bäst bör utformas för att främja vägledning och förutsägbarhet i en annars obestämd generalklausul. Principiellt med möjlighet att stämpla villkor som oskäliga i sig framfördes i lagmotiven. Kausistiskt, baserat på omständigheterna i det enskilda fallet, menade flertalet remissIn connection with the preparation of section 36 of the Swedish Contracts Act, different views were expressed as to how the courts' decisions should best be formulated in order to promote guidance and hence predictability in an otherwise indefinite general clause. Principally designed with the possibility of stamping contract terms as unreasonable in itself, it was argued in the law motives. B

Climate-focused study abroad relying on high-emitting travel poses a dilemma between study abroad and emission reductions. This study employs the three spheres of transformation investigating this dilemma through coding syllabi (n=156,) surveying educators (n=9,) and interviewing (n=14) Climate Action Network for International Educators (CANIE) affiliates considering whether studying climate chang

Objectives: Pregnancy can influence immune control of Mycobacterium tuberculosis infection (MtbI). We recently reported an association between MtbI and pregnancy complications, particularly severe preeclampsia, in a registry-based cohort of women originating in tuberculosis-endemic countries screened for MtbI in Swedish antenatal care, implying a potential role of MtbI for the development of preec

The rising prevalence of type 2 diabetes among migrant populations from low- and middle-income countries (LMICs) living in high-income countries (HICs) presents a significant public health challenge. Migrants often experience lifestyle changes, socioeconomic disadvantages and barriers to accessing healthcare, which can increase their risk for type 2 diabetes. This review explores the prevention an

Objective: To identify and quantify risk factors for incident knee osteoarthritis (KOA) across the lifespan. Methods: This systematic review and meta-analysis identified eligible studies from seven electronic databases and three registries. Longitudinal cohort studies or randomised controlled trials evaluating participants who developed incident symptomatic and/or radiographic KOA were included. T

The atomic lattice plays a critical role in the emergence of high-𝑇𝑐 superconductivity in cuprates. While the dynamics associated with electron-lattice coupling typically unfold on picosecond-to-femtosecond timescales, we present an x-ray photon correlation spectroscopy investigation on an optimally doped La-based cuprate that reveals a strong response of kilosecond-scale lattice relaxation dyna

The provision of military and armed security services typically is the monopoly domain of the state. With the end of the Cold War legitimate private firms, however, expanded as worldwide providers of military and security services. The proliferation of private military companies echoes back to pre-modern eras when it was customary for state rulers to allocate force and security through the market.

The formation of ESDP (European Security and Defense Policy) is one of the most important building blocks shaping the European security structure and the European integration process since the beginning of the 21st century. Even though the integration engine was injured by the rejection of the European Constitutional Treaty in France and the Netherlands, the ESDP can be seen as currently one of th

Elevators has for a long period of time been regarded as unsafe to use as a means of egress. This is an opinion that has shifted in the last couple of years as technical solutions has been found to the initial problems when using elevators as an escape route. This report investigates the possibility to replace a staircase with emergency elevators as a means of egress in a buildning. The report als

Svensson (1997) föreslår att centralbanker på grund av implementerings- och utvärderingssvårigheter hos inflationsmål även bör ha ett mål för inflationsprognoser. Han argumenterar för detta med hjälp av en teoretisk modell som antar att den korta räntan, som centralbanken kontrollerar, påverkar BNP-gapet med en periods fördröjning, vilket sedan påverkar inflationen efter ännu en period. För att ma