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Introduction: The purpose of this study was to investigate potential associations between body composition and current smoking in young healthy women from high-risk families. Cigarette smoke contains >7000 chemicals of which 69 are established carcinogens and smoke also acts as an aromatase inhibitor. Smoking is now recognized as a carcinogen for the breast and influences both risk and prognosis.

An increasing number of patients with central nervous system (CNS) tumour could survive to reproductive age. However, it is largely unknown whether the history of CNS tumour might affect pregnancy outcome. We aimed to explore the risk of being born pretem among children of CNS tumour survivors. By linking several nationwide registers in Sweden, we identified 1369 children whose parents were childh

Alzheimer’s disease is linked to amyloid β (Aβ) peptide aggregation in the brain, and a detailed understanding of the molecular mechanism of Aβ aggregation may lead to improved diagnostics and therapeutics. While previous studies have been performed in pure buffer, we approach the mechanism in vivo using cerebrospinal fluid (CSF). We investigated the aggregation mechanism of Aβ42 in human CSF thro

Background and Objective: Waste in clinical trials remains rife. We developed an economic model to predict the cost of trials based on input costs, duration, power, number of sites, recruitment eligibility and consenting rates. Methods: We parameterised the model for three proxy placebo-controlled surgical trials using data from a systematic review, a bespoke cost survey, and from the literature.

The quantum many-body interactions in one-dimensional spin- 1/2 systems are subject to Tomonaga-Luttinger liquid (TLL) physics, which predict an array of multiparticle excitations that form continua in momentum-energy space. Here we use inelastic neutron spectroscopy to study the TLL spin dynamics in SrCo2V2O8 , a compound which contains weakly coupled spin-1/2 chains of Co atoms, at 0.05 K and in

AIMS: Diagnosing heart failure with preserved ejection fraction (HFpEF) remains challenging, particularly in older individuals. We hypothesized that machine learning (ML) approaches could improve diagnostic accuracy compared with HFpEF scores.METHODS: We evaluated the diagnostic performance of four supervised ML algorithms (random forest [RF], extreme gradient boosting [XGBoost], support vector ma

Antimicrobial resistance in pathogenic mycobacteria remains a critical challenge due to poor drug penetration through their complex cell wall, which necessitates prolonged multidrug regimens. Mycobacteriophages encode a lytic machinery that can disrupt this barrier. In this research article, we describe a modular mycolysin platform combining phage enzymes Lysin A and Lysin B with outer membrane-pe

Wide-angle neutron scattering analysed using empirical potential structure refinement (EPSR) was used to investigate how aromatic ring structure influences micelle self-assembly in two anionic surfactants: sodium 4-heptylbenzene sulfonate (SHBS) and sodium 5-heptylfuran-2-sulfonate (SHFS). Both surfactants formed globular micelles in aqueous solutions at 0.2 M but differed significantly in micelle

Objectives: To evaluate the impact of the 2018 switch from PCV13 to PCV10 in Sweden’s childhood immunisation programme on the serotype distribution of Streptococcus pneumoniae.MethodsRespiratory tract (RT) S. pneumoniae isolates (n=1615; 2020–2023) were serotyped, tested for antimicrobial susceptibility and compared with invasive pneumococcal disease (IPD) isolates (n=397) and PCV13-era data (2016

Electrostatic energy plays a pivotal role in the minimization of the free energy of self-assembling oppositely charged ions. This is a fundamental principle that guides the formation of aggregates and the separation of phases characterized by a stoichiometric balance between the opposite charges. However, this study unveils the self-assembly of catanionic nanotubes from a mixture of oppositely cha

Background Multimorbidity, the co-occurrence of two or more non-communicable diseases (NCDs), is common and has been linked to venous thromboembolism (VTE). Whether multimorbidity diagnosed in primary-care is associated with incident VTE remains unclear. We aimed to examine this association. Methods Multimorbidity was defined using Swedish primary-care data. Individuals without prior VTE were incl

Background: The C-reactive protein-triglyceride-glucose index (CTI) has been proposed as a novel biomarker for insulin resistance and inflammation. However, its role in the progression trajectory of cardiometabolic multimorbidity (CMM) remains unclear. We aimed to investigate the involvement of the CTI in the CMM progression trajectory. Methods: This prospective study included 266,049 individuals

CONTEXT: Melatonin regulates circadian rhythms and influences glucose metabolism. Altered melatonin secretion may contribute to the pathogenesis of type 2 diabetes (T2D), but prospective population-based evidence is scarce.OBJECTIVE: To examine whether low nocturnal melatonin secretion is associated with an increased risk of incident T2D in adults.METHODS: This prospective cohort study, with follo

OnlineOpen: Hybrid Open Access Option 9 Author Invitation Workflow Affiliations Funders OnlineOpen selection Sign license All authors are guided through these steps in this order, regardless of how they enter the workflow (via email link, Author Services Dashboard, etc.) Author Workflow ▪ Step 1: Invitation Email ▪ Step 2: Log in to Author Services Dashboard ▪ Step 3: Confirm Affiliations ▪ Step 4

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/wiley_open_access_workflow_authors.pdf - 2026-06-04

Microsoft Word - AudraDiersLawson.doc 4TH INTERNATIONAL CONFERENCE ON CRISIS COMMUNICATION IN THE 21ST CENTURY OCTOBER 7–10, 2015 IN HELSINGBORG, SWEDEN 1 Whose Crisis is it Anyway? Examining Complexity in Blame Attribution and Reputational Risk in the Airline Industry Audra Diers-Lawson1, Simona Ivanova2, Yue Wan3, Eleni Sotiorpoulou4, Salma Al-Hajiri5 1 Manchester Business School, University of

https://www.isk.lu.se/sites/isk.lu.se/files/audradierslawson.pdf - 2026-06-04

1 är du intresserad av utvecklingsfrågor? vill du ge din examen en internationell profil? sök sidas mfs- resestipendium ht-2015 senast 6 oktober 2015 kl 12:00 Tidigare stipendiater har rest till Nicaragua och studerat hur man på kommunalnivå har hanterat transitionen till en mer hållbar energiförsörjning; till Namibia och undersökt lokala orsaker och effekter av desertifiering; till Bogotá, Colomb

https://www.keg.lu.se/sites/keg.lu.se/files/mfs_utlysning_ht_15.pdf - 2026-06-04

1 är du intresserad av utvecklingsfrågor? vill du ge din examen en internationell profil? sök sidas mfs- resestipendium vt-2015 senast 16 april 2015 kl 12:00 Tidigare stipendiater har rest till Nicaragua och studerat hur man på kommunalnivå har hanterat transitionen till en mer hållbar energiförsörjning; till Namibia och undersökt lokala orsaker och effekter av desertifiering; till Bogotá, Colombi

https://www.keg.lu.se/sites/keg.lu.se/files/utlysning_vt15.pdf - 2026-06-04