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Observation of Genuine High-dimensional Multi-partite Non-locality in Entangled Photon States

Quantum information science has leaped forward with the exploration of high-dimensional quantum systems, offering greater potential than traditional qubits in quantum communication and quantum computing. To advance the field of high-dimensional quantum technology, a significant effort is underway to progressively enhance the entanglement dimension between two particles. An alternative effective st

Arts on prescription intervention for primary healthcare patients with poor mental health or social isolation : a mixed-method study

Background: Primary healthcare providers are increasingly challenged in supporting patients with psychosocial needs. Arts on Prescription (AoP) has been shown to improve primary healthcare patients’ mental health wellbeing. The aim of the current study is to understand the psychosocial effect of participating in an Arts on Prescription programme. Methods: A total of 112 primary healthcare patients

Delivery of Ulva rigida extract by bicontinuous cubic lipid nanoplatforms for potential photodynamic therapy against pancreatic cancer

Ulva rigida is a widely available marine algae representing a valuable biomass from which natural photosensitizers (chlorophylls) can be obtained in an environmentally friendly manner using a green microwave-assisted extraction technique. If properly loaded in biocompatible nanoformulations, such highly hydrophobic chlorophylls with photosensitizing activity may constitute effective drugs useful i

Proteomic analysis of serum samples after cardiac arrest : Rationale and design of a TTM-trial substudy

Background: A pilot study investigating proteomic profiles from 78 patients from the Target Temperature Management after Out-of-hospital Cardiac arrest (TTM) trial revealed 35 proteins associated to functional outcome, and six proteins associated to targeted temperature management at 33 °C. We present the protocol for a study investigating proteomic profiles in the full cohort of the TTM-trial bio

Belimumab concentrations and immunogenicity in relation to drug effectiveness and safety in SLE within a Swedish real-world setting

Objectives: Studies supporting therapeutic drug monitoring to biopharmaceuticals in SLE are scarce. We aimed to assess anti-drug antibody (ADA) occurrence in belimumab-treated SLE patients and associations between belimumab concentrations and clinical response, serological outcomes and adverse events. Methods. We included 100 patients treated with intravenous belimumab. Clinical data and biologica

Molecular architectures of glycosylated dendronized bottle brushes in action : Biocompatibility and anti-amyloidogenic activity of pseudo-glycodendrimers

Glycopolymers are versatile materials for biomedical and healthcare applications, e.g., as carrier and polymeric therapeutics. Especially, the topology and surface composition of such materials play a key role in being promising materials in the anti-amyloidogenic interventions. Herein, 2nd and 3rd generation of pseudo-glycodendrimers (PGDs), based on hyperbranched polyester core with different su

Transition from spontaneous to explicit symmetry breaking in a finite-sized system : Bosonic bound states of an impurity

The presence of a single attractive impurity in an ultracold repulsive bosonic system can drive a transition from a homogeneous to a localized state, as we here show for a one-dimensional ring system. In the few-body limit, the localization of the bosons around the impurity, as seen in the pair correlations, is accompanied by low-lying modes that resemble finite-sized precursors of Higgs-Anderson-

Packaging impact on consumer experience : voice of the E-customer

With the growth of e-commerce, understanding the nuances of packaging performance and consumer expectations has become essential to enhancing the customer experience. In e-commerce, packaging is a key component of the overall consumer experience, directly influencing perceptions and expectations. Despite its importance, packaging often remains overlooked and is significantly understudied. This exp

Lactoferrin-derived peptide PXL01 impacts nerve regeneration after sciatic nerve reconstruction in healthy and diabetic rats

INTRODUCTION: Although advanced surgical techniques are available, satisfactory functional outcomes after peripheral nerve injuries are uncommon. Hence, immune-modulating factors such as PXL01, a lactoferrin-derived peptide that improves axonal outgrowth in injured human digital nerves, have gained attention. We previously reported a short-term immunosuppressive effect of PXL01 after the repair of

Prospective Assessment of Clinically Relevant Fluid Balance Thresholds Associated With Postoperative Complications in Advanced Ovarian Cancer

Background: Reliable data on optimal fluid management in the perioperative period for patients with advanced ovarian cancer undergoing cytoreductive surgery is limited. These patients often present with malignant ascites and are prone to significant fluid shifts perioperatively. For this reason, our objective was to define clinical targets for optimal fluid balance and determine whether initial as

Mini-review of the EAT-Lancet planetary health diet and its role in cardiometabolic disease prevention

Human diets play a crucial role in both human health and environmental sustainability. In 2019, the EAT-Lancet Commission on healthy diets from sustainable food systems introduced the EAT-Lancet planetary health diet, a universal reference diet designed to promote human health while minimizing environmental degradation. It is a predominantly plant-based dietary pattern, rich in whole grains, veget

Recovery of constitutive immune function after migratory endurance flight in free-living birds

Strenuous physical activity can negatively affect constitutive innate immune function (CIF), the always present first line of defence against pathogens. CIF is non-specific, and thus vital when encountering novel pathogens. A lowered CIF likely increases the risk of infection and disease. Migratory birds engage in truly extreme physical activity during their endurance flights, however, little is k

Protection Against Pneumonia Induced by Vaccination with Fimbriae Subunits from Klebsiella pneumoniae

Background: Klebsiella pneumoniae infections pose a great burden worldwide, causing high morbidity and mortality, which are worsened by the increase in multidrug-resistant strains. New therapeutic/prophylactic strategies are urgently needed to overcome antibiotic resistance and reduce the health and economic impacts of diseases caused by this pathogen. Fimbriae are important virulence factors invo

Solution and Interfacial Properties of Cyclic Containing Anionic Surfactants

The bulk micellar and surface adsorption behaviour of a bio-derived cyclic-containing anionic surfactant, sodium tetradecyl furan sulfonate (STFS), has been studied in this work. To determine its viability as an alternative to petrochemically derived surfactants in detergents, the self-assembly andadsorption properties were measured both alone and in binary and ternary mixtures with a common anion

Synthesis, Growth Mechanism, and Photocatalytic Properties of Metallic-Bi/Bi13S18Br2 Nano-Bell Heterostructures

We report the synthesis of bell-shaped Bi/Bi13S18Br2 metal/semiconductor heterostructures as a photocatalyst based on nontoxic and Earth-abundant elements. Their unique morphology arises from a multistep growth process, involving (1) the nucleation of Bi13S18Br2 nanorods, (2) the reduction of a metallic-Bi domain on their surface induced by N,N-didodecylmethylamine, and (3) the heterostructure acc

Randomised crossover controlled trial of dietary interventions for glycaemic control when body weight is kept stable

A Palaeolithic diet is an efficacious dietary approach for glycaemic control in type 2 diabetes. Causal mechanisms are body weight loss and glucometabolic effects from differences in included food groups, macronutrient composition, fibre content, and glycaemic load. The aim was to test the hypothesis that characteristic food group differences between a Palaeolithic and a diabetes diet would cause

Prognostic performance of preoperative cardiac troponin and perioperative changes in cardiac troponin for the prediction of major adverse cardiac events and mortality in noncardiac surgery : A systematic review and meta-analysis

Background Increased postoperative cardiac troponin (cTn) independently predicts short-term mortality. Previous studies suggest that preoperative cTn also predicts major adverse cardiovascular events (MACE) and mortality after noncardiac surgery. The value of preoperative and perioperative changes in cTn as a prognostic tool for adverse outcomes has been sparsely investigated. Methods and findings

DA.Vra1-congenic rats display increased gene expression and Schwann cell apoptosis but unaffected nerve regeneration compared to parental DA rats after sciatic nerve injury and repair

Introduction: The rat Vra1 locus, containing glutathione S-transferase alpha 4 (Gsta4), regulates the degeneration of central nervous system (CNS) neurons in toxin-, protein-, and injury-based models. We hypothesize that Piebald Virol Glaxo.1AV1 (PVG) alleles in Vra1 confer protection and increased axonal outgrowth after peripheral nerve injury and repair. Methods: DA rats (n = 14) and DA rats wit

Hur verkligt är verkligt värde? En studie om informationsasymmetri vid börsintroduktioner utifrån IFRS 13 värderingshierarki

Titel: Hur verkligt är verkligt värde? En studie om underprissättning vid börsintroduktioner Seminariedatum: 2 juni 2023 Kurs: FEKH69 – Examensarbete i redovisning på kandidatnivå Författare: Oskar Brunnéd, Simon Sandström, Jamal Shamma Handledare: Liesel Klemcke Syfte: Studien syftar till att undersöka ifall underprissättningen vid börsintroduktioner på Stockholmsbörsen och Nordic Growth Ma