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Growth and immune development—fundamental parts of any organism's ontogeny—depend critically on nutrient availability, particularly on essential amino acids that support protein synthesis and physiological processes. However, environmental variation can reduce prey diversity and nutrient quality, producing suboptimal diets that lack essential amino acids, potentially constraining development. In t

Background: The incidence, aetiology, and outcome of unplanned intensive care unit admission after elective colon cancer surgery remain unclear. This study investigated the incidence of, and factors associated with, unplanned intensive care unit admission following elective colon cancer resection in Sweden. Methods: This nationwide retrospective registry study included adult patients undergoing el

ObjectivesAutoantibodies against tissue transglutaminase (tTG) are serological markers of celiac disease. The aim was to study the applicability of human leukocyte antigen (HLA)-genotyping and tTG autoantibodies in the screening of celiac disease in a longitudinal birth cohort followed to age 15 years.MethodsIncluded were 13,860 HLA-DQ-genotyped children at birth and previously invited to a screen

ObjectivesOur aim was to study the association between residential land cover and greenness during childhood and risk of developing celiac disease (CeD).MethodsThe Celiac Prediction in Skåne study prospectively followed 5969 human leukocyte antigen (HLA)-genotyped children born 2001–2004 who were screened for CeD at ages 3, 9, and 15 years in Skåne, Sweden. Among these, 138 (2.3%) children only in

Background and aims: We examined whether the excess cardiovascular disease (CVD) risk among adults with steatotic liver disease (SLD) subtypes could be reduced or eliminated through joint control of low-density lipoprotein cholesterol (LDL-C), lipoprotein(a) [Lp(a)], and high-sensitivity C-reactive protein (hs-CRP). Methods and results: This prospective cohort study included 291,995 participants f

This meta-analysis and systematic review examined the effects of psychedelic substances on death anxiety, specifically evaluating whether psychedelic experiences are associated with statistically significant reductions in death anxiety. A systematic search identified 8 studies suitable for meta-analysis and 10 additional studies for systematic review. Using a random-effects model, the meta-analysi

Lung transplantation (LTx) remains the only curative treatment for patients with end-stage lung disease, yet long-term outcomes remain inferior to those of other solid organ transplantations, with a 5-year survival below 70%. Major contributors to this limited outcome include primary graft dysfunction (PGD), the leading cause of early mortality, chronic lung allograft dysfunction (CLAD), and low u

Early-life adversity negatively affects morbidity and survival in late life, but knowledge is limited about effects on women’s reproduction and reproductive health. To deepen our understanding of the full effects of disease exposure in early life, including long-term consequences, we study women’s reproductive outcomes and their offspring’s health. Using the Scanian Economic Demographic Database a

Bacteriophages exert strong selective pressure on bacterial populations and play a central role in shaping microbial evolution. In response to phage predation, bacteria have evolved diverse antiphage defence mechanisms that interfere with viral replication through a wide range of molecular strategies. Recent genomic studies have revealed a rapidly expanding repertoire of candidate defence systems,

Transition Cities as Niches for Radical Change How to organise Transition work in cities – what can Malmö, Sweden, learn from Bristol, England? Two case studies on the Transition movement By: Tina Nyfors tina.nyfors@gmail.com Supervised by: Pernille Gooch pernille.gooch@hek.lu.se Barry Ness barry.ness@lucsus.lu.se June 2011 A thesis submitted to Lund University in partial fulfilment for the degree

https://www.lumes.lu.se/sites/lumes.lu.se/files/nyfors_tina_thesis_2011.pdf - 2026-05-10

OBJECTIVE: Screening for abdominal aortic aneurysm (AAA) using ultrasound in men reduces aneurysm-related mortality. Ambulatory screening and surveillance procedures facilitated by point-of-care ultrasound (POCUS) may improve adherence to screening programs. This proof-of-concept study evaluated whether infrarenal aortic diameter (IAD) can be accurately and interchangeably measured using handheld

The study aimed to investigate the unique lipid composition of Mycobacterium bovis BCG and its potential to enhance antimicrobial efficacy of lipid-coated mesoporous silica particles (MSPs). The bacterial lipids (BL) were extracted with petroleum ether and analyzed via LC-MS, revealing a complex mixture of phospholipids, including cardiolipin, phosphatidylcholine, phosphatidylethanolamine, and tri

BACKGROUND: The evidence linking sugar intake to cardiovascular disease risk remains largely inconclusive, with variations observed across different subgroups of sugar intake. In addition, studies on genetic markers of sugar intake are scarce, especially for different sugar subgroups.OBJECTIVE: This genome-wide association study (GWAS) aimed to investigate genetic variants associated with the inta

INTRODUCTION: Epidemiological evidence suggests the association of preserved ratio impaired spirometry (PRISm) at baseline with the risk of heart failure (HF), however, the associations between transitions of PRISm and incident HF remain to be clarified. Furthermore, the causal relationship and underlying biological mechanisms linking PRISm and HF are unclear.OBJECTIVES: This study aimed to invest

Additives such as binders and hydrophobic agents are commonly introduced into the fibrous Gas Diffusion Layer (GDL) of proton exchange membrane fuel cells to enhance mechanical strength and facilitate water management. However, the effect of additive/fiber content and surface wettability on water removal, oxygen diffusion, and heat conduction remains insufficiently understood. In this work, we dev

Background: Multimorbidity, i.e. two or more non-communicable diseases (NCDs), has been associated with venous thromboembolism (VTE), but whether multimorbidity is a predictor for incident VTE is unknown. Aims: To examine the associations between multimorbidity and its severity with risk of incident VTE, and examine the association between nine different disease clusters and incident VTE. Methods:

Whether monetary incentives to change behavior work and how they should be structured are fundamental economic questions. We overcome typical data limitations in a large-scale field experiment on vaccination (N = 5,324) with a unique combination of administrative and survey data. We find that guaranteed incentives of $20 increase uptake by 13 percentage points in the short run and 9 in the long ru

BACKGROUND: Perfluoroalkyl substances (PFAS) are stable chemicals used in various applications. PFAS exposure has been associated with lower birth weight and immunological effects in children, and limited evidence further suggests adverse neurodevelopmental effects. Previous studies show that PFAS cross the placental barrier during pregnancy leading to prenatal exposure of the fetus. Research on t

ESP18-0638

Background and objective: There is limited literature on the relationship between cardiovascular health (CVH) and kidney stones. This study aims to compare the association of Life's Simple 7 (LS7) and Life's Essential 8 (LE8) with kidney stone prevalence. Methods: A cross-sectional analysis was conducted utilizing NHANES data (2007–2018). Participants aged ≥20 yr with a history of kidney stones an