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Objective: To determine the prevalence, change in breathlessness status over time, and risk factors for disabling and persistent disabling breathlessness in relation to treatments in chronic obstructive pulmonary disease (COPD). Materials and methods: Longitudinal analysis of data from the Swedish National Register of COPD with breathlessness measured using modified Medical Research Council (mMRC)

Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study https://doi.org/10.2337/dc17-0238 OBJECTIVE Wetested the associations between genetic backgroundand selected environmental exposures with respect to islet

https://www.teddy.lu.se/sites/teddy.lu.se/files/03022018_679_70_mp45_krischer_diab_care_2017.pdf - 2026-05-09

Aims: Studies have shown the association between personal history of diabetes mellitus (DM type 1/2) and risk of colorectal cancer (CRC). This study aims to find the association between the family history of diabetes and CRC risk. Methods: This large nationwide cohort study leveraged data from several Swedish nationwide registers (follow-up: 1964–2018) to compare the risk using standardized incide

We report tunneling spectroscopy and transport measurements in superconducting Al and ferromagnetic insulator EuS bilayers. The samples display remanent spin splitting, roughly half the superconducting gap, and supercurrent transport above the average paramagnetic limit. We interpret this behavior as arising from the interplay between two characteristic length scales: the superconducting coherence

Ordered arrays of nanocrystals, called supercrystals, have attracted significant attention owing to the collective quantum effects arising from the coupling between neighboring nanocrystals. In particular, lead halide perovskite nanocrystals are widely used because of the combination of the optical properties and faceted cubic shape, which enables the formation of highly ordered supercrystals. The

Background: Childhood (< 20 years) nervous system tumors manifest in some rare cancer syndromes but how commonly they present with familial clustering between various histological types is not well known at a nation-wide level. Our aim is to enhance understanding of familial risks in childhood nervous system cancers. Methods: We used the Swedish population and cancer data from years 1958–2021 to a

Background: Parents face mental health challenges following their child's cancer diagnosis. However, it is unknown whether parental mental illness following a childhood cancer diagnosis influences the child's mortality.Patients and methods: Using several nationwide registers in Sweden, we identified children diagnosed with cancer between ages 0 to 14 from 2005 to 2016. Parental mental illness was

Introduction: Comorbidities and public health conditions in haemophilia are receiving increasing attention. Aim: To analyse the prevalence of comorbidities and mortality in people with haemophilia (PwH) compared to matched controls in subgroups (factor consumption and sex). Methods: This study used longitudinal individual-level data (11 years) from national registers in three Nordic countries (Den

Familial clustering of lung cancer (LC) is related to shared smoking habits but the contribution of other potential factors such as sex or histology is not well known, and these are the subjects of the present study in Sweden. Family relationships (from Multigeneration register) and diagnosed cancers (from Cancer registry) were obtained from the national registers from 1961 to 2021. The overall fa

Med anledning av klimatkrisen har EU-kommissionen presenterat En ny handlingsplan för den cirkulära ekonomin – För ett renare och mer konkur-rens-kraftigt Europa. Det huvudsakliga syftet med handlingsplanen är att skapa förutsättningar för att ställa om till ett klimatneutralt samhälle och att frikoppla ekonomisk tillväxt från resursanvändning. I handlingsplanen anges därför att förutsättningar föDue to the climate crisis, the European Commission has presented A new Circular Economy Action Plan – For a cleaner and more competitive Europe. The main purpose of the action plan is to create a framework for sustainable products to change into a climate neutral society and decoupling economic growth from resource use. The action plan therefore states that conditions for reuse and repair, among o

Denna uppsats undersöker möjligheten till straffrättsligt ansvar vid använd-ning av högautomatiserade fordon (nivå 4–5 enligt SAE:s indelning) enligt svensk rätt. Specifikt fokuserar uppsatsen på tillämpligheten av 1 § Trafik-brottslagen (TBL) och undersöker om en fysisk person kan hållas ansvarig för vårdslöshet i trafik när ett autonomt körsystem är i kontroll. En rättsdogmatisk metod används meThis thesis paper explores the possibility of criminal liability under Swedish law when highly automated vehicles (level 4–5 according to SAE's classifica-tion) are used. It focuses on whether a physical person can be held responsi-ble for careless driving under Section 1 of the Traffic Offences Act (TBL), even when the vehicle is controlled by an autonomous driving system. A legal dogmatic me

Background: Although up to 25% of proximal humeral fractures are isolated greater tuberosity fractures (IGTFs), comprehensive epidemiological data are lacking. Objectives: Describe the epidemiology and time trends of IGTF in Malmö, Sweden, 1944–2020. Methods: We identified IGTF in Malmö residents (≥18 years) by reviewing relevant radiology examinations during 17 sample years from 1944 to 2020. Fra

Purpose: Consistent, accurate postoperative guidance is crucial for early recovery and patient satisfaction in urology, especially for radical prostatectomy (RP) patients. However, patients often receive inconsistent information, highlighting the need for standardized, evidence-based postoperative care guidelines. Materials and Methods: We conducted a comprehensive review and evaluation of current

BACKGROUND: Some per- and polyfluoroalkyl substances (PFAS) such as perfluorohexane sulfonic acid (PFHxS), perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) are very long-lived in humans, with serum half-lives of several years. In PFAS hot spots, such as Ronneby, Sweden, high exposures over time have led to markedly elevated serum PFAS levels, which may result in health risks

Due to their high reactivity, organolithium and organomagnesium addition to ketones is usually performed under inert atmosphere at low temperature. Recent work has shown that, by dissolving the substrate in deep eutectic solvents (DES), these processes can be carried out on the benchtop, in air at room temperature. Surprisingly, the organometallic reagent, added to the DES from an organic solu

InP quantum dots have emerged as a promising ecofriendly alternative to cadmium-based QDs for next-generation display applications. However, red-emitting InP QDs synthesized via aminophosphine precursors still suffer from broad emission spectra and limited stability. In this study, we present a strain-engineered InP/ZnSe/ZnSexS1-x/ZnS QD structure featuring a gradient alloyed ZnSexS1-x shell that

Introduction: Human papillomavirus (HPV) infection is associated with tonsillar and base-of-tongue squamous cell carcinomas (TSCC/BOTSCC). We evaluated the relative risk (RR) of TSCC/BOTSCC in the husbands of women with anogenital cancer using the Swedish family database. Methods: The Swedish family database includes 3.5 million families and 16 million individuals identified since 1932 and linked

Objective: A diagnosis of childhood cancer is profoundly devastating for families, with well-recognized effects on parental mental health. However, its impact on parental somatic health remains poorly understood, particularly regarding potential long-term cumulative burden. These persistent somatic diseases require frequent clinic visits for ongoing management and adversely affect parents' quality