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Abstract – Background: Endocrine science remains underrepresented in European Union research programs despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritization. At national funding level, endocrine societies report limited or little attention of na

Maternal alloantibody-induced hemolytic disease of the fetus and newborn (HDFN) remains a significant concern worldwide. Alloimmune HDFN can be pathogenetically named by the specific alloantibodies involved. Moreover, four mechanistic pathway types are generally recognized in clinical practice: classical or extravascular hemolysis; immune-pressure-escaped, also known as antibody-mediated antigen-m

Background: Asthma with low levels of type 2 (T2) biomarkers is poorly understood. Objective: To characterize severe asthma phenotypes and compare changes in asthma outcomes from pre- to postbiologic treatment along a gradient of T2 involvement. Methods: This was a registry-based cohort study including data from 24 countries. Biomarker distribution (blood eosinophil count, fractional exhaled nitri

Background: Research on the primary care management of back pain in children and young people (CYP) is scarce. Sociodemographic factors may influence presentation and management, potentially contributing to disparities in care and outcomes. This study aimed to describe the management of back pain in CYP and examine associations with sociodemographic characteristics. Methods: Data were extracted fr

The socioeconomic health gradient has widened since the mid-21st century, but the role of childhood neighborhoods remains underexplored. Most neighborhood studies on health are cross-sectional, and longitudinal research is lacking.We analyze how socioeconomic neighborhood conditions in childhood influence cause-specific deaths in adulthood. We use uniquely detailed geocoded longitudinal microdata

A blood group may be defined as an inherited character of the red cell surface detected by a specific alloantibody. This definition would not receive universal acceptance, since cell surface antigens on platelets and leucocytes might also be considered blood groups (see Chapter 4), as might acquired characteristics on red cells defined by autoantibodies or polyagglutinins. The definition is suitab

https://www.soch.lu.se/sites/soch.lu.se/files/2023-01/Skuldtyngd%20-%20Policy%20brief%202%20Jan%202023.pdf - 2026-05-25

Esophageal squamous cell carcinoma is linked to alcohol drinking, whereas esophageal adenocarcinoma risk is increased by overweight and obesity. Both histologies are directly related to tobacco smoking. We wanted to define the risk of esophageal cancer by histology and length of stay among immigrants in Sweden. The nationwide Swedish Family Cancer database (2010 version: data on cancers originate

Information on mortality in ankylosing spondylitis (AS) is scarce. Our study therefore aimed to assess: (1) mortality in AS versus the general population, and (2) predictors of death in the AS population.

Objective. Formal joint assessments are critically important to improve rheumatological care of patients with RA. The aim of this study was to determine the usefulness of patient-recorded 28 tender joint counts (TJCs) and swollen joint counts (SJCs) using a tablet personal computer and to explore the possibility of using patient-recorded data to calculate 28-joint DAS (DAS-28) and EULAR response.

Background Increased cancer risk after psoriasis has been observed in previous studies, whereas little is known about the prognosis in cancer patients with previously diagnosed psoriasis. Objectives We aimed at examining the cancer-specific and overall mortality among psoriatic cancer patients compared with the reference population. Methods The population-based Swedish registers were used to ident

OBJECTIVES: We investigated whether menopausal vasomotor symptoms (VMS) are related to an adverse cardiovascular risk profile. Furthermore, we examined the association between estradiol levels and VMS, and whether an association between VMS and cardiovascular risk factors can be explained by estradiol levels. STUDY DESIGN: We used data from a Swedish population-based sample of 5857 women, aged 50-

Background: In Sweden, a person with substance abuse can be reported to the social services for an investigation about commitment to coercive care. After a change in legislation, municipalities varied greatly in the ratio of commitments/reports compared with the period before the legislation was amended. Aims: The primary aims of this study were first, to investigate whether subjects from municipa

Background: The coding of histology of nervous system (NS) tumors with various degrees of malignancies differs between cancer registries, whereby the comparison of incidence rates from one registry to another seems difficult. No study has systematically defined whether the change in the risk of NS tumors upon immigration in adulthood varies by subsite or histology. Therefore, we aimed to address t

BACKGROUND: The incidence of acute cardiovascular and cerebrovascular events in patients treated for complicated or uncomplicated peptic ulcer disease (PUD) has not been ascertained completely. METHOD: All patients with in-hospital treatment due to PUD between 1987 and 2007, who did not have any past history of acute or chronic cardiovascular or cerebrovascular disease, were identified through the

BACKGROUND: Cancer and venous thromboembolism (VTE) are associated disorders. In the present nationwide study, we analyzed the risk of cancer in siblings, offspring and spouses of individuals hospitalized for VTE (and vice versa) with the aim of identifying shared familial risk factors for cancer and VTE. MATERIAL AND METHODS: The Multigeneration Register was linked to the Swedish Hospital Dischar

Objective: Previous studies suggest that low birth weight is associated with thyroid autoimmunity and hypothyroidism in later life, but the potential effect of preterm birth, independent of fetal growth, is unknown. Our objective was to determine whether preterm birth is independently associated with medically treated hypothyroidism in young adulthood. Design/Participants: National cohort study of

Zöller B, Li X, Sundquist J, Sundquist K. (Center for Primary Health Care Research, Lund University, Malmö, Sweden; Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, CA, USA). Familial risks of unusual forms of venous thrombosis: a nationwide epidemiological study in Sweden. J Intern Med 2010; doi: 10.1111/j.1365-2796.2010.02326.x. ABSTRACT.: Objective. This is