Filetype
Microscopic colitis (MC) is a disease with intestinal mucosal inflammation causing diarrhea, affecting predominantly middle-aged women. The etiology is unknown, but increased prevalence of autoimmune diseases in these patients has been described, although not compared with controls or adjusted for confounding factors. The aim of this study was to examine the prevalence of common diseases in patien
Background: It remains unclear whether the increased risk of colorectal cancer (CRC) associated with obesity differs by gender, distribution of fat, tumour location and clinical (TNM) stage. The primary aim of this study was to examine these associations in 584 incident colorectal cancer cases from a Swedish prospective population-based cohort including 28098 men and women. Methods: Seven anthropo
IMPORTANCE The introduction of biological tumor necrosis factor inhibitors has improved the treatment of rheumatoid arthritis (RA) but at a substantial cost. These drugs have been shown to lead to superior radiological outcomes compared with a combination of conventional disease-modifying antirheumatic drugs over 2 years. OBJECTIVE To investigate whether radiological superiority translates into be
Introduction: Using time-limited trials of low-dose, sustained-release morphine to reduce chronic breathlessness to evaluate net effects may generate opioid withdrawal symptoms if medication is ceased. This sub-study of a larger randomized, placebo-controlled, double-blind trial aimed to evaluate if this occurred. Methods: People with modified Medical Research Council breathlessness scores of 3 or
Background:Utilization of the maternal continuum of care (CoC)—comprising adequate antenatal care (ANC), skilled birth attendance, and postnatal care (PNC)—is critical for improving maternal and child health outcomes. However, dropout from the CoC remains substantial in Bangladesh, with women discontinuing services at different stages of pregnancy, delivery, and postpartum care.Objective:This stud
BackgroundSuicide is a leading cause of premature mortality worldwide, but the impact of system-level mental health resources remains unclear despite the central role of psychiatric inpatient care and declining bed capacity. Prior research has yielded inconsistent findings with limited control for confounding. We aimed to estimate the effect of psychiatric inpatient bed availability on suicide mor
Antibiotic resistance poses a global threat. Antibiotics are administered to 80-90% of terminally ill patients but evidence of their effectiveness in improving survival or symptom relief at the end of life (EOL) is scarce. To determine the proportion of deceased patients that continue antibiotic treatment after documented EOL discussion and the decision to prioritise symptom relief over active tre
Background: The prevalence of urinary incontinence (UI) and fecal incontinence (FI) are conditions that increase with age. Apart from few larger studies data on prevalence and severity of UI and FI is scarce, especially among the > 80 yrs. and data of birth cohort effects is lacking. Methods: The purpose of this study was to evaluate birth cohort effects on prevalence of UI and FI in the general o
Objective: To examine temporal changes in late diagnosis of HIV (LD) among migrant and non-migrant people with HIV in Sweden 2003–2023 and to assess demographic and socioeconomic risk factors for LD in these two populations. Methods: People with HIV diagnosed with HIV-1 in Sweden 2003–2023 were included (n = 6278). LD was defined as a first CD4+ T-cell count <350 cells/μL or an AIDS-defining event
PURPOSE: The systolic blood pressure (SBP) response to exercise reflects cardiovascular health, with both exaggerated and blunted responses linked to adverse outcomes. Prior studies relied typically on peak SBP or two-point slopes for evaluation. We aimed to identify distinct SBP responses from full times-series recorded during maximal, graded exercise and assess their clinical determinants and pr
Background:Support, Monitoring, and Reminder Technology for Mild Dementia (SMART4MD), a customized tablet app, was developed to improve or maintain the quality of life of people with mild cognitive impairment (MCI) and their informal caregivers.Objective:This study conducts an 18-month economic evaluation of the SMART4MD app, in addition to standard care, compared with standard care alone in Swede
Handbok för IT-systemägare och IT-systemförvaltare vid LU feb 22 Handbok i systemförvaltning FÖR IT-SYSTEMÄGARE OCH IT-SYSTEMFÖRVALTARE | 2022-02-04 BIRGITTA LASTOW 1 Handbok för IT-systemägare och IT-systemförvaltare vid LU Versionshistorik 0.1 2021-08-06 Första utkast 1.0 2022-02-04 Första version efter kommentarer Arbetsgrupp: • Karin Ekborg-Persson • John Westerlund • Birgitta Lastow • Karl Ag
Postadress Box 117, 221 00 Lund Besöksadress Medicon Village, Scheeletorget 1,223 63 Lund Telefon 046-222 12 51, 046-222 00 00 E- post linus.wiebe@innovation.lu.se Webbadress www.lu.se Univers i tetsstyrelsen Ägardirektiv för LU Holding AB Fastställes av universitetsstyrelsen 2024-06-18 Detta dokument avser att på ett övergripande plan reglera hur Lunds universitet (LU) ska utöva sin roll som ägar
https://www.innovation.lu.se/sites/innovation.lu.se/files/2024-08/A%CC%88gardirektiv%20LU%20Holding%20AB%20240618.pdf - 2026-05-28
Aims: To assess lung function at early school age in children delivered at very early gestation owing to intrauterine growth restriction and abnormal foetal blood flow (IUGR). Methods: Spirometry was performed at median age 8.4 (range 6.5-10.7) years in 31 children born preterm with IUGR (PT-IUGR) with a median (range) birth weight (BW) of 650 (395-976) g and median (range) gestational age 27 (24-
AIMS: To investigate the association between socioeconomic status, unemployment and self-rated psychological health, taking economic stress and horizontal trust into account. Design/setting/participants/measurements: The 2008 public health survey in Skåne is a cross-sectional postal questionnaire study with a 55% participation rate. A random sample was invited and 28,198 persons aged 18-80 partici
In the broader spectrum of back pain, inflammatory back pain (IBP) is a symptom that may indicate axial spondyloarthritis (SpA). The objectives of this study were to determine the frequency of current IBP, as a hallmark sign of possible axial SpA, in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) and other SpA and to compare self-reported health between the groups with curren
Aim: To compare two different regimens for children diagnosed with type 1 diabetes: hospital-based care or hospital-based home care (HBHC), referring to specialist care in a home-based setting. Method: The trial took place in Sweden with a randomized controlled design and included 60 children, aged 3-15 years. After 2-3 days with hospital-based care, children were randomized to either continue
